RoosterBio Inc.

?? A study published in Science Advances from Oregon Health & Science University, Wyss Institute at Harvard University, and State University of Campinas shows that perivascular cells (PCs) play a crucial role in how tiny blood vessels respond to changes in their surroundings. Using lab-engineered capillaries, the group led by Professor Luiz Bertassoni found that PCs influence vessel leakage and inflammation, especially in stiffened, diseased tissues. The findings highlight a new, possibly targetable mechanism via NOTCH3 to modulate vascular health in diseases like atherosclerosis, neurodegeneration or liver fibrosis. RoosterBio was pleased to see its MSCs used in the methods of this work. Read it here: https://lnkd.in/e9V4_tdT #capillary #pericytes #mesenchymalstemcells #fibrosis #perivascularcells #liverfibrosis #celltherapyresearch #inflammation #celltherapy

??? Join RoosterBio's upcoming webinar, Exploring MSC-EV Attributes: Analytical Comparison of Tissue Sources and Production Platforms, on Wednesday, April 2nd at 11:00 AM (ET). To maximize therapeutic potential, #extracellularvesicles (EVs) from mesenchymal #stromalcells (MSCs) need established quality attributes. This webinar will explore how analytical tools can assess the impact of production process choices and tissue source on the quality attributes of MSC-derived EVs. Register here: https://lnkd.in/eZnYmy4V #criticalqualityattributes #advancedtherapies #exosomes #stemcelltherapy #cqas #bioproduction #bioprocessing #celltherapymanufacturing

Biological components in conditioned media are a consistent problem during downstream processing of #exosomes. That's why RoosterBio developed AgentV?-DSP, a solution designed to address filtration problems and increase particle yield up to 10-fold. Watch our latest webinar on-demand to learn more: https://lnkd.in/eH8BhX-s #Extracellularvesicles #downstreamprocessing #webinar #exosome #microvesicles #bioprocessing #bioprocess

QuickShip? DSP takes conditioned media and rapidly processes it into vials of either concentrated extracellular vesicles/enriched secretome or purified extracellular vesicles. Learn how to leverage RoosterBio's advanced equipment and industry-leading expertise to enable faster results without needing to acquire complex downstream processing capabilities.?? https://lnkd.in/e8aTQRPT #extracellularvesicles #exosomes #downstreamprocessing #bioprocessdevelopment #celltherapy #secretome #advancedtherapies

RoosterBio is accelerating access to extracellular vesicles (EVs, aka exosomes) for translational research and first-in-human trials. To unlock its full potential, MSC-EV production must align with CMC and regulatory standards. Our latest study compares conditioned medium across scalable platforms to optimize EV manufacturing for the clinic. Explore our findings here: https://lnkd.in/emmvf9XW #exosomes #extracellularvesicles #bioprocessing #celltherapymanufacturing #bioproduction #assay #bioprocessmedia #cmc #conditionedmedia

Our latest blog and accompanying webinar detail how AgentV?-DSP can help you significantly improve #exosome yield while maintaining quality. In the last decade, biotechnology has been quietly perfecting the infrastructure to rapidly “amp up” #advancedtherapy bioprocesses. This downstream processing treatment?is one of many innovations that is "changing the tune” for cell therapies and bioproduction. Learn more: https://lnkd.in/eK4eVhaq #extracellularvesicles #bioprocess #celltherapy #stemcells #stemcelltherapy #bioproduction #downstreamprocessing

Scalable #extracellularvesicle (EV) purification requires complex equipment, expertise, and investment in process development. Take advantage of RoosterBio’s optimized EV downstream processing solutions instead with QuickShip? DSP, and achieve higher EV yields faster. Learn more and request your QuickShip DSP price here.?? https://lnkd.in/e8aTQRPT #extracellularvesicles #exosome #exosomes #downstreamprocessing #advancedtherapies #bioprocessing

Congratulations to the following 3 Value Award winners! These Roosters were nominated by their peers for going above and beyond to exemplify RoosterBio's core values: ?? Christina Jenkins' dedication to #CustomerFocus is clear. She is committed to making sure that our customers get the highest quality, graciously accommodates last minute requests, and makes sure that the customer is happy. ??? Matthew Rehmann demonstrates #Integrity in every facet of project management. Understanding the status of our technologies, programs, and bandwidth is critical. He provides accurate descriptions with a keen eye towards technical and commercial success. ?? Megan Brittain goes above and beyond to support her team. When training, Megan dedicates time to shadow each team member and make sure things are going well. We appreciate Megan’s #Teamwork and dedication to making sure all projects are executed smoothly.

?? In the last decade, biotechnology has been quietly perfecting the infrastructure to rapidly “amp up” advanced therapy bioprocesses. RoosterBio’s AgentV?-DSP is one of many innovations that is "changing the tune” for cell therapies and bioproduction, offering 10-fold greater efficiency for MSC-derived exosome manufacturing. Our latest blog and accompanying webinar detail how this downstream processing treatment can help you significantly improve exosome yield while maintaining quality. Read it here: https://lnkd.in/eK4eVhaq #exosomes #extracellularvesicles #bioprocessing #biomanufacturing #celltherapymanufacturing #microvesicles #advancedtherapies

https://lnkd.in/efvZkUvh ?? This bioRxiv preprint by Dr. Ross Marklein and colleagues at FDA-CDER and The University of Georgia explores how mesenchymal stromal cell-derived #extracellularvesicles (MSC-EVs) might one day help treat neurodegenerative diseases by modulating brain pericytes, key players in blood-brain barrier integrity and inflammation. They developed a novel method to assess pericyte shape changes, while showing that MSC-EVs could down-regulate hallmarks of neuroinflammation. RoosterBio is proud to support this important research via its MSCs, bioprocess expertise, and high-performance culture media. #neurodegenerativedisease #inflammation #celltherapy #exosomes #celltherapyresearch #regenerativemedicine #stemcelltherapy #stromalcells