Come check us out at BioProcess International US West in San Diego, CA both today and tomorrow! Dennis and Gary will be manning the booth and ready to answer any questions you may have about HaLCon, a purpose-built liquid chromatography system that provides data that correlates to off-line HPLC?in about five minutes. Informa #BPIWest
关于我们
RedShiftBio is redefining the analysis of protein, mabs, peptides, RNA, and LNP structure and concentration. RedShiftBio has developed a proprietary life sciences platform combining our Microfluidic Modulation Spectroscopy (MMS) and expertise in high-powered quantum cascade lasers that provide ultra-sensitive and ultra-precise measurements of molecular structure. These structural changes affect critical quality attributes governing the safety, efficacy, and stability of biomolecules and their raw materials. This combination of technologies is available to researchers in our fully-automated Aurora and Apollo systems and is backed by a global network of sales, applications, service, and support teams to address all market needs. Alongside our commitment to further innovation in the formulations and development space, RedShiftBio also supports biopharmaceutical manufacturing with HaLCon, our bioprocess analytics platform, purpose-built to measure protein titer at time of need. Led by an experienced management team with a proven track record of success in both large instrumentation companies and commercializing disruptive technologies, RedShiftBio is here to support your research, development, and manufacturing goals. Our instruments can be found in the majority of the leading biopharmaceutical companies and CDMOs in the world. We also run product demonstrations and process samples in the StructIR Lab, located in our Boxborough, MA headquarters, as well as at partner sites including the Wood Centre in Oxford, UK, Spectralys/UCB in Brussels, Belgium, and at Sciex laboratories in Redwood Shores, CA. RedShiftBio is backed by Waters Corporation, Illumina Ventures, Technology Venture Partners, and one undisclosed leading life science company.
- 网站
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https://redshiftbio.com/
RedShiftBio的外部链接
- 所属行业
- 生物技术研究
- 规模
- 11-50 人
- 总部
- Boxborough，MA
- 类型
- 私人持股
- 创立
- 2005
- 领域
- Quantum Cascade Lasers、Molecular Spectroscopy、DSC - Differential Scanning Calorimetry、 CD-UV – Circular Dichroism Ultraviolet、HPLC-SEC - High Performance Liquid Chromatography-Size Exclusion Chromatography、 UV BCA – Ultraviolet BiCinchoninic Acid assay、Protein Characterization、FT-IR、Biotherapeutics Analysis、Biosimilar、Formulation、Secondary Structure、Biologics、Biophysical Characterization、Aggregation、Stability、Antibodies、Drug Discovery、Process Development、titration、Chromatography、Bioprocessing Analytics和Protein A Affinity Chromatography
地点
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主要
获取路线
80 Central Street
US，MA，Boxborough，01719
RedShiftBio员工
动态
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Reminder: RedShiftBio's 2025 Structure Lab Grant Program is LIVE! This is your opportunity to win a free project with our StructIR Lab worth up to $30,000 and get your hands on MMS data with your own samples. Additionally, all applicants get a $500 discount to use on a project of your own design, good for six months. Applications are due by March 31st, 2025 and you can find out more about the program here: https://lnkd.in/e2_q8WTC
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Thank you to Bingchuan Wei for sharing your work Genentech looking at changes in higher order structure and thermal induced dissociation of RNA aggregates in real time using our Aurora Tx! We're so excited to see your work and what else you do with MMS in the future! Check out the full publication here: https://lnkd.in/euteAt_2
I am thrilled to announce our latest publication, "Real-Time Monitoring of Higher-Order Structure of RNAs by Temperature-Course Size Exclusion Chromatography and Microfluidic Modulation Spectroscopy," now available in Analytical Chemistry. This work is the result of a fantastic collaboration between the talented teams between #Genentech Shijia Tang, Lance Cadang, Bifan Chen, Jenny Wang and Kelly Zhang and RedShiftBio team Eugene Ma, Valerie Ivancic Collins, Ph.D., Scott Gorman, Richard Hailin Huang, Ph.D. and Maria MA, Ph.D.. You can access the full publication here: https://lnkd.in/gvfCnhRP In this study, we took an in-depth exploration of the biophysical characterization of the higher-order structure (HOS) of RNAs. By developing two complementary native analytical techniques—Size Exclusion Chromatography (SEC) and Microfluidic Modulation Spectroscopy (MMS)—we successfully monitored changes in RNA HOS and thermal induced dissociation of RNA aggregates in real time. We established a beautiful correlation between the separation and spectroscopic results. We believe that the combination of SEC and MMS provides a comprehensive toolkit for the biophysical characterization of RNA HOS under native conditions, offering valuable insights for optimizing candidates and screening formulations in RNA therapeutic development. Additionally, Richard Hailin Huang, Ph.D., Valerie Ivancic Collins, Ph.D., and I have contributed to a #MyACSCover story for our study. We depicted a thermal ramping MMS setup on the ground, symbolically dissociating double-stranded RNA in the flow into two #AuroraTX in the night sky. Enjoy the story!
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Well said Richard DiVirgilio. Buffers matter a lot when looking at structure. Check out this great app note demonstrating our MMS-IR technology built into our latest Aurora TX instrument. Characterize your higher order structures and base pairing in their native buffers. More info here: https://lnkd.in/d6eB7sn9
?? Buffers Matter More Than You Think Pick the wrong buffer, and your protein might not behave the way you expect. But how do you measure those structural changes with real confidence? We used MMS (Microfluidic Modulation Spectroscopy) to analyze lysozyme in water, PB, PBS, and Tris. The results were clear. Tris had the biggest impact, followed by PB, then PBS. MMS detected these shifts with far greater sensitivity than traditional methods. No more guesswork, just data-driven buffer selection. Check out the full app note below. ?? RedShiftBio #Biotech #ProteinStability #MMS #StructuralBiology #LifeSciences
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This week, we’re at the 4th Annual mRNA Analytical Development & Quality Control Summit, a part of the World RNA Events Series! Come stop by our booth to check out AuroraTx and how you can utilize it as a part of your development and quality processes to look at mRNA structure. More information about the summit can be found here:?https://lnkd.in/eJQhhAK2
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Hello academic friends again. Stop by booth 215 at the Biophysical Society conference in LA if you are attending. It’s hopping! #bps2025 Scott Gorman PhD wil be presenting our latest applications during the poster session. We are also promoting or latest StructIR Labs project grant. Stop by and learn more!
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Announcing the 2025 RedShiftBio Structure Lab Grant Program! This is your chance to win a free project from our StructIR Lab worth up to $30,000! All proposals submitted by the deadline will also receive a $500 credit to put toward your own StructIR Lab project within the next 6 months. Proposals are due by March 31, 2025. More information can be found here: https://lnkd.in/eZy5wAZw We look forward to seeing how you want to utilize MMS and the AuroraTX in your proposals!?
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RedShiftBio转发了
Looking forward to celebrating 50 years of protein science @LorneProteins. Visit our booth #18, SPIN TO WIN competition is back !! Win $2000 award!!! See our poster "Structural Characterization and Comparison of Temperature and Pressure Stress on a Protein Library Across pH and Concentration Using Microfluidic Modulation Spectroscopy"... RedShiftBio
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Boston Institute of Biotechnology ranked Halcon #1 in Ease of Use, Precision, Accuracy, and Cost of Use in a recent study when quantifying antibody titer of FC fusion and IGG antibodies in comparison to Elisa and Protein A HPLC. Hear from?Matthew Sousa's recent presentation at BPI and find out how Halcon, from Redshiftbio, can give you quantitative results that can save valuable time and cost! https://lnkd.in/eAsNg48K