Profluent

Attending the Alliance for Regenerative Medicine Cell and Gene Meeting on the Mesa next week? Meet with our CBO Hilary Eaton, PhD to explore how we can build together. #CGMesa24 #cellandgenetherapy

Reagent drop ?? After debuting OpenCRISPR-1, the world’s first AI-created and open-source gene editor, we’re thrilled to share that the tools detailed in our bioRxiv preprint have been added to the Addgene repository. ?? Access the plasmids here: https://lnkd.in/eRfvq4Fz Read more about OpenCRISPR-1: ?? Paper: https://lnkd.in/esbdquHt? ?? Blog: https://lnkd.in/gGs-Qgt7 #GeneEditing #GeneticMedicines #OpenSourceScience #ReagentDrop

Our CBO Hilary Eaton, PhD joined Matthew Pillar on the Business of Biotech podcast to talk about her exposure to CRISPR when the technology was still in its infancy, her drive to directly impact patient lives - as well as her own personal connection to rare disease, and how Profluent’s use of AI is flipping the drug development paradigm upside down. Check it out: https://lnkd.in/eWcsX5ED

Catch our CEO Ali Madani during a panel discussion on foundational models in biology as part of The State of AI in Drug Discovery virtual summit on Oct. 30, organized by Fay Lin, PhD and Genetic Engineering & Biotechnology News. Register for free ?? https://lnkd.in/gnGGAK_r

Attending the West Coast AI Summit: The Transformative Power of AI in Pharmaceutical R&D, presented by California Life Sciences (CLS) and Johnson & Johnson Innovation? Don’t miss our CBO Hilary Eaton, PhD in a panel discussion about the role of AI in drug discovery on October 3rd. Registration info here ?? https://bit.ly/4ekPZXU

Our CEO Ali Madani spoke with Christos Evangelou, PhD, BCMAS at CRISPR Medicine News about our vision behind releasing the world’s first AI-created and open-source gene editor, OpenCRISPR-1. Check out the full piece ?? https://lnkd.in/eDgZwrgb

Here’s another peek at our offsite adventures last month.??? From exploring Sausalito to visiting the Golden Gate Bridge and hitting a hiking trail together, we had a blast soaking up the great views and good company. It’s been a truly incredible year for Profluent, and we left energized for what’s to come.???

Our team recently gathered for an inspiring offsite in SF, where we engaged in a fireside chat on the development of ChatGPT with Fraser Kelton (formerly OpenAI) and heard bench to bedside perspectives on gene editing from Tirtha Chakraborty (former Head of Hematology at CRISPR Tx) and Victoria Gray (a sickle cell patient advocate and the first person to be cured with the CRISPR medicine Casgevy). In between programming, we got to enjoy each other’s company and capped off a great week with dinner in Sausalito.

ICYMI: Great to see Ali Madani at the annual AI x Bio Summit organized by Decoding Bio at the New York Stock Exchange last week. He was joined by Matej Macak, Philipp Lorenz, Tom Sercu and moderator Renee Y. in a panel to discuss foundation models in biology – and what’s next on the horizon for #AI in drug discovery.

“[With proseLM] we can take the fine control of structure-based approaches and the broad scope of sequence-based approaches to look at the best of both worlds.” Our head of protein design at Profluent Jeffrey Ruffolo spoke with Genetic Engineering & Biotechnology News about our new proseLM model. Read more about his conversation with Fay Lin, PhD and our CEO Ali Madani in the full article. ?? https://lnkd.in/eTGaR6iK #AI #GenerativeAI #ProteinDesign #CRISPR