Discover how the PXB-mouse model can help you understand the entire HBV lifecycle. Read our new case study to find out how this brings us a step closer to developing a complete cure for hepatitis B: https://lnkd.in/evrw9JJT #hbv #preclinical #humanizedliver
PhoenixBio
生物技术研究
Higashi-Hiroshima City，Hiroshima 1,285 位关注者
Realize the Future of High-Quality Translational Animal Models
关于我们
PhoenixBio established its proprietary chimeric mouse model, the PXB-mouse?, with a highly humanized liver through years of research and development. With the addition of fresh, isolated human hepatocytes, PXB-cells?, the applications of our products and study services are as wide-ranging as our clients’ research goals. The PXB-mouse animal background (cDNA-uPA/SCID) makes for a robust, consistent model that maintains up to 95% stable human hepatocyte engraftment. The reconstituted humanized liver features structural and biological characteristics commonly observed in normal human livers. The model has proven to be a world-wide gold standard for Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) research, but usage is expanding in the fields of: . Drug Metabolism and Pharmacokinetics, · Human Specific Hepatotoxicity, · Oligonucleotide and Gene-based Therapeutics, · HBV & HBV/HDV, · NASH/NAFLD, · Other human liver-related research fields. PXB-cells? are approximately 95% pure human hepatocytes freshly isolated from the PXB-mouse?. They feature long-term stability of up to 40 days, and allow for consistent supply from the same donor. One unique feature of PXB-cells? and PXB-mice is the ability to directly compare in vitro and in vitro data from the same human donor. With over 300 scientific publications to its credit, the PXB-mouse is the world’s most widely used chimeric mouse model with a humanized liver. A high replacement index, lifespan of up to 2 years, and no secondary drug to maintain mouse liver injury means that your data can translate better to humans than ever before. Please visit our website at https://www.phoenixbio.com/ to learn more about our model and inquire about our offered products and services.
- 网站
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https://www.phoenixbio.com/
PhoenixBio的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- Higashi-Hiroshima City，Hiroshima
- 类型
- 上市公司
- 创立
- 2002
- 领域
- Biotechnology、Contract Research、Study Services、Project Management、Logistics、Drug Development、Drug metabolism、Safety、Toxicity、Pharmaceuticals、Efficacy testing、Humanized model和Hepatocytes
地点
PhoenixBio员工
动态
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PhoenixBio supports Rare Disease Day to help shine a light on the impact of rare diseases in our global community. Our humanized liver models, the PXB-mouse and PXB-cells, provide translational tools that bridge the gap from preclinical to clinical research and enable the development of new therapies for rare liver diseases. We take pride in partnering with researchers and biotech innovators who share our mission: to bring hope to the 300 million people affected by rare diseases worldwide. Today, on #RareDiseaseDay, we stand with the global community pushing the boundaries of what’s possible.
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Interested in a humanized liver mouse model? Need high quality human hepatocytes? PhoenixBio will be attending AASLD and can answer your questions on how the PXB-mouse and PXB-cells can enhance your liver research program! Visit us at Booth #1831 to learn more! Or visit our website to see related abstracts: https://lnkd.in/e_Suwfgr #AASLD #TLM24 #TheLiverMeeting #HumanizedMice #Preclinical #Hepatocytes #Hepatology #ViralHepatitis #HBV #HDV #GeneTherapy #Oligonucleotides
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The PhoenixBio team is attending ESGCT! Come join us at Booth B18 to learn more about the PXB-mouse and PXB-cells. Humanized liver models allow direct evaluation of human targeting gene therapies and provide translational insights to enhance your research programs. Book a meeting with our team here: https://lnkd.in/gqwfCa3K #ESGCT2024 #GeneTherapy #CellTherapy #humanizedliver #HumanizedMice #Preclinical #Hepatocytes
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Interested in learning how the PXB-mouse can supercharge your HDV Research? Meet with us in Milan at DeltaCure 2024 to find out how our humanized liver mouse model can model all stages of the HBV and HDV lifecycles. Our PXB-cells can also provide a complementary high quality human hepatocyte platform for in vitro viral hepatitis studies.?Click here to book a meeting with our experts: https://lnkd.in/exMsH4Jc #DeltaCure #HDV #HBV #HumanizedMice #Preclinical #Hepatocytes #DeltaVirus #ViralHepatitis #Liver
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We’re excited to be here in Montreal to get the latest updates in the fast moving field of Oligonucleotides!? Come join the PhoenixBio team at Booth #3-1 to learn how the PXB-mouse and PXB-cells can enhance your preclinical research. Our humanized liver mouse model and fresh human hepatocytes provide an unparalleled translational platform to advance your studies. #ots24 #oligomeeting #oligotherapeutics #oligonucleotide #OTS #HumanizedMice #Preclinical #Hepatocytes
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It’s great to be here at the North American ISSX and JSSX Meeting in lovely Hawaii! We’re looking forward to seeing some new and familiar faces as we immerse ourselves in the very latest in translational xenobiotic research. Connect with us at booth #112, where our experts will be on hand to discuss how we can help unlock greater translational insights from your preclinical studies. And, don’t forget to check out some of our latest research, summarized in poster #P217 “Liver Humanized Chimeric PXB-Mouse as a Model to Predict Human Renal Toxicity by Aldehyde Oxidase Dependent Metabolism of SGX523” #ISSX #JSSX #Xenobiotics #Metabolism #Pharmacokinetics #ADME #DMPK #DrugDiscovery #HumanizedMice
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Are you a viral hepatitis researcher at the International HBV Meeting here in Chicago? Then come and meet the PhoenixBio team! We’ll be here to answer your burning questions about how humanized liver mice and fresh human hepatocytes can help you gather highly translational insights during preclinical testing. Book your meeting today: https://lnkd.in/eK_TNuRi #Hepatitis #HBV2024 #Preclinical #HBVmeeting #HumanizedMice
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We’re here at EUROTOX 2024! Are you here, too? Then don’t miss your chance to meet the PhoenixBio team at booth #8. Swing by and discover how our humanized liver mouse model or our fresh human hepatocytes can help enhance your toxicity studies to unlock more physiologically relevant insights. #EUROTOX2024 #Toxicology #Preclinical #HumanizedMice
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Today, on World Hepatitis Day, we're reminded that "It's time for action" against viral hepatitis. Every 30 seconds, someone loses their life to a hepatitis-related illness. This sobering statistic underscores the urgent need for continued research, improved diagnostics, and innovative treatments in our collective fight against the viruses. At PhoenixBio, we're committed to supporting this vital cause. Our PXB-mouse, a humanized liver mouse model, for example, enables researchers to study the entire viral life cycle of hepatitis B, hepatitis C, and hepatitis D with high translational relevance. By providing tools that bridge the gap between preclinical and clinical research, we aim to accelerate the development of new therapies and bring hope to millions affected by hepatitis. Together, we can work towards the WHO's goal of eliminating viral hepatitis by 2030. #WorldHepatitisDay #Hepatitis #WorldHealthOrganization
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