Pharmaron

Just 2 weeks to go! Don’t miss Pharmaron’s Integrated Drug Discovery webinar - ??????????????????????: ???? ???????????????????????? ?????????????? ???????????????? ???? ???????? ???????????? ?? ????????? December 5th at 8am PT / 11am ET / 4pm GMT In this session, experts Mike Waring (Newcastle University) and Sebastien Campos (Pharmaron) will explore the growing role of macrocycles in drug design, highlighting their unique advantages, challenges, and practical applications through case studies. ?? Curious about what’s in store? ?????????? this quick overview from Kevin Foote, VP of Drug Discovery Services Europe, for a sneak peek into the webinar! ?? Register now: https://lnkd.in/gXZ3Cdiq #Pharmaron #DrugDiscovery #Macrocycles #Webinar #DrugDesign

That's a wrap on BOS Manchester 2024!? We’re thrilled by the success of the event, filled with fantastic networking opportunities, insightful talks, and a truly welcoming atmosphere. It was a pleasure connecting with so many brilliant minds in the field. Until next time, learn more about Pharmaron’s services by visiting our website: https://lnkd.in/ewVsK4aU. #Pharmaron #BOSManchester #Networking #LifeSciences #PharmaInnovation

???????? ???? ?????? ?????? ???????????????? ???????? ??????????????! Brain Penetration Concepts, Challenges and Mitigation Strategies for Biologics and Novel Constructs. How Low Can You Go? ?? ????????: December 11th ? ????????: 8am PT/11am ET/ 4pm GMT We’re excited to feature three leading experts in the field who will share their insights into brain penetration strategies for biologics: ?? James Yates: Scientific Director at GSK and leads the nonclinical PKPD modelling team in DMPK, Preclinical Sciencs. He has a background in mathematics and engineering (University of Warwick, UK) and has 20 ?years’ experience in drug discovery and development, particularly in oncology. He has published 90 papers on translational PKPD. He has a particular interest in the application of mathematical modelling for translation from nonclinical to patients and between patient populations.? ?? David Fairman: Dave is currently CPMS Translational head at GSK and is accountable for oversight and guidance of early phase clinical pharmacology studies. His background is in translational pharmacology with a specialisation in biologics including TMDD modelling and assay selection best practise. ?? Scott Summerfield: Senior Director, Pharmaceutical Metabolism at Pharmaron Don’t miss the opportunity to deepen your understanding of this critical area in drug development! ?? ???????????????? ??????: https://lnkd.in/eRcpeE79 #DMPK #BrainPenetration #Pharmaron #Webinar #DrugDevelopment

Mark your calendars. Pharmaron will attend the 2024 NEDMDG Winter Meeting on Dec. 4 at Takeda in Cambridge, MA. Join us for insights on radiolabeled mass balance studies and CYP/non-CYP reaction phenotyping trends. Click here to schedule a meeting with our team:?https://lnkd.in/dKu8mUS2 Learn more about our US Lab Services, RLS, DMPK, and Bioanalysis capabilities here:?https://lnkd.in/dwYdQNgy

Looking to optimise your drug development strategy? Don’t miss Sanjeev Sood and Simon Taylor from Pharmaron at BOS Manchester 2024! Their talk, "Formulation and PK Integration: A Fast-Track to Drug Development Success," will provide valuable insights for accelerating timelines and ensuring success. ??? When: Tuesday, 26th November, 3 PM ?? Where: BOS Manchester Connect with the Pharmaron team at Booth 11 to learn more about how they can support your R&D goals! #DrugDevelopment #Pharmaron #BOSManchester2024

Join Pharmaron at Phacilitate, Advanced Therapies Week in Dallas, January 20–23, 2025! Visit us at Booth #675 to learn more about our CGT CRO and CDMO capabilities. Our team is here to discuss how we can support your advanced therapy program with expertise spanning discovery to commercialization, including analytical testing, safety studies, and scalable manufacturing solutions. Schedule a meeting with our experts to explore how we can help you accelerate your pathway to regulatory approval and commercialization. Schedule a meeting at your convenience:?https://lnkd.in/eAYEURPb Let’s advance the future of cell and gene therapy together. #Pharmaron #AdvancedTherapiesWeek #Phacilitate?#CellAndGeneTherapy #CGT #ATW25

Thank you to everyone who joined our webinar on Pharmaron’s AAV Production Platform! We had an engaging session discussing how our innovative approach can streamline the journey of AAV products to BLA/MAA submission. Key highlights included: > The therapeutic potential of AAV > Essential platform considerations > Strategies to overcome production challenges If you missed it, don’t worry! You can access the on-demand recording here: https://lnkd.in/dkeTmB6K #CGT #Pharmaron #LifeSciences #CDMO #IND

Join us for our next ?????????????? ?????????????????? ?????????????? on Thursday, November 28, 2024, at 4:00 pm (China Standard Time).?? ? ?????? ???????????????????? ???? ?????? ???????????????????? ?????????? ?????????????????? ?????? ??????-?????????????? ??????????????????? Prof. Michael Waring? Chemistry, School of Natural and Environmental Sciences,? Newcastle University, UK? ? ???????????????? for the webinar: https://lnkd.in/gy3D-NQA In this lecture, Prof. Mike Waring will discuss his approach to DEL synthesis using micelle-mediated chemical reactions that leads to much improved efficiency allowing the synthesis of higher fidelity DELs. Prof. Mike Waring has employed this technology to develop a range of library forming reactions, including Suzuki, amide, Buchwald, Heck and Sonogashira couplings as well as reductive aminations and hydrogenation. Prof. Waring has employed this chemistry in the synthesis of screening libraries but also to poised DELs for fragment expansion, termed NUDELs. This approach has been demonstrated with the development of a potent and highly ligand efficient lead for BRD4 from a weak fragment whose affinity arises from synergistic protein-ligand interactions that could not have been discovered by other means. #VirtualLecture #Pharmaron #Hitgeneration #DNA #DEL

Find out more about ?????????? ?????????????????????? in our upcoming DMPK webinar scheduled for ??????????????????, ???????????????? ????????? ?????? ????/???????? ????/?????? GMT. We will be discussing the CNS penetration of molecules where the rate of passage into the brain is comparable to the associated clearance processes, key aspects of their bioanalysis, and?the importance of complementary pharmacological measurements.? ? By registering once, you will have access to and receive updates for each webinar in the series. ?? ???????????????? ?????? ?????? ???????????? here: https://lnkd.in/gnF442Jj ? ? For more information and to watch previous webinars, check out our page: https://lnkd.in/g5ACuqDp??? ? #DMPK?#webinar #CNS #BrainPenetration

Connect with Pharmaron at BioFIT 2024! We’re excited to announce that our team, Hélo?se Beutier, Nicolas Duchemin, and Severine Marrony, will be attending BioFIT in Lille, France, on December 3rd and 4th! This is a fantastic opportunity to discuss how Pharmaron’s expertise in drug discovery and development can accelerate your projects. Don’t miss the chance to connect! ???????????????? ?? ?????????????? with us here: https://lnkd.in/gsYxSFd3 See you in Lille! ???? #BioFIT #Pharmaron #LifeSciences #DrugDiscovery #Innovation