Pharma GenLabs Pharmacogenomics laboratory Z code certification 81418

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State of the science in personalized medicine. This is a great overview article on pharmacogenomics in the relationship to precision medicine and the advantages this technology holds for patients around the world.

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Pharmacogenomics Brings Precision Medicine to Long-Term Care and Nursing Home facilities The goal of precision medicine, to treat each patient individually, is becoming a reality in nursing homes and long-term care facilities thanks to advancements in pharmacogenomics testing. Pharmacogenomics (sometimes called pharmacogenetics) is a field of research that studies how a person’s genes affect how he or she responds to medications. “Its long-term goal is to help doctors select the drugs and doses best suited for each person,” says the National Institute of General Medical Sciences. What is Pharmacogenomic Testing? Pharmacogenomics is a mouthful, but the Mayo Clinic points out that the word precisely describes drug-gene testing as it is a combination of “pharmacology” (the study of the uses and effects of medicine) and “genomics” (the study of genes and their functions). “Pharmacogenomic tests look for changes or variants in these genes that may determine whether a medication could be an effective treatment for you or whether you could have side effects to a specific medication,” says the Mayo Clinic. Side effects to medication can be serious, sometimes even fatal, especially for older patients. “You’ve seen the alarming statistics: there are an estimated 100,000 deaths and upwards of two million serious adverse drug reactions (ADRs) in the United States each year related to prescription drug use, costing the healthcare industry in excess of $136 billion annually according to the Food and Drug Administration,” says the Institute for the Advancement of Senior Care publication. “Older individuals are particularly at risk for ADRs due to polypharmacy, co-morbidities and a host of age-related variables and physiological changes that alter drug absorption and metabolism.” Genes are instructions, written in DNA, for building protein molecules. Different people can have different versions of the same gene. Each version has a slightly different DNA sequence. Some of these variants are common, and some are rare. “Scientists know that certain proteins affect how drugs work. Pharmacogenomics looks at variations in genes for these proteins,” says the National Institute of General Medical Sciences. “Such proteins include liver enzymes that chemically change drugs. Sometimes chemical changes can make the drugs more—or less—active in the body. Even small differences in the genes for these liver enzymes can have a big impact on a drug’s safety or effectiveness.” A report released in January 2022 shows the global pharmacogenomics services market projected to reach approximately $9.4 billion by 2031 from $5.1 billion in 2020, at a CAGR of 5.71 percent. View full post