Perspective Therapeutics

Our first human imaging with [203Pb]PSV359 suggests rapid uptake and sustained retention in multiple cancer types. PSV359 is a novel peptide developed by our in-house discovery team which targets Fibroblast Activation Protein-α (FAP). Imaging was performed by Dr. Ishita Sen’s group at Fortis Memorial Research Institute - India. Further information will be available in upcoming presentations and publications. ? https://lnkd.in/ePh7Z6Zh #nuclearmedicine #radiopharma #oncology

NEWS ALERT! Perspective has opened its new manufacturing facility for the production of its 203Pb- and 212Pb-labeled radiopharmaceuticals in Somerset, New Jersey. Today, we are celebrating the first shipment and patient dosing from this state-of-the-art facility! Learn more here: https://lnkd.in/eRjU9Wxn #radiopharmaceuticals #radiopharma #leadmanufacturing

Lead-212 isotope purification can be achieved through simple chemical separation. Perspective harnesses the natural decay chain of Radium-224, effectively de-risking the supply chain. This breakthrough not only streamlines the production process but also ensures a consistent and reliable supply, pushing the boundaries of what's possible in isotope-based applications. Disclaimer: https://lnkd.in/eyqc_hrs

Lead-212 offers unique advantages in therapeutic applications, primarily because it can grow naturally from a Radium-224 source without requiring irradiation. Here’s why this is significant: 1. Natural Growth: Lead-212 can be obtained through the natural decay of Radium-224. This eliminates the need for irradiation, which is a complex and cumbersome step required for producing many other radioisotopes. 2. Simplified Production: The natural growth of Lead-212 from Radium-224 simplifies the production process, reducing costs and potential bottlenecks associated with irradiation facilities. 3. Increased Safety and Efficiency: Avoiding irradiation not only streamlines the production process but also enhances safety and efficiency. It reduces the handling of radioactive materials and the associated risks. 4. Consistent Supply: With a natural source like Radium-224, the supply of Lead-212 is more reliable and consistent, ensuring availability for therapeutic use. By leveraging the natural growth of Lead-212 from Radium-224, we can overcome the challenges posed by irradiation, leading to more efficient and safer production of therapeutic isotopes. Disclaimer: https://lnkd.in/eyqc_hrs

We're #hiring a new Senior Director, Medical Monitor in United States. Apply today or share this post with your network.

We're #hiring a new Director, CMC Operations in Somerset, New Jersey. Apply today or share this post with your network.

Thorium-228 plays a crucial role in the supply chain for therapeutic isotopes like Lead-212. Here are three key points highlighting its importance: 1. Naturally Occurring in Mining Waste: Thorium-228 is naturally found in mining waste, providing a stable and reliable supply source. 2. Byproduct of Nuclear Processes: Thorium-228 is also a byproduct of nuclear processes, further ensuring a consistent and dependable supply. 3. Storage Capabilities: Thorium-228 can be stored for up to 2 years, offering excellent flexibility and reliability in isotope availability. By leveraging the natural abundance and storability of Thorium-228, we can enhance the robustness and efficiency of therapeutic isotope supply chains. Disclaimer: https://lnkd.in/eyqc_hrs

Last month, our CEO, Thijs Spoor, participated in an Endpoints virtual panel with Jeevan Virk, Therapeutic Area Strategy Head – Radioligand Therapy, Strategy, & Growth of Novartis, Phillippe Bishop, CMO of Abdera Therapeutics, and Umar Mahmood, Chief of Nuclear Medicine & Molecular Imaging at Massachusetts General Hospital, moderated by Lei Lei Wu, on The Radiopharma Boom at #ESMO2024! Watch the recap here -> https://lnkd.in/enw2ZNiy

We're #hiring a new Radiopharmaceutical Marketing Manager in United States. Apply today or share this post with your network.

We're #hiring a new Process Engineer in Somerset, New Jersey. Apply today or share this post with your network.