Want to learn about the methods the #PTN uses to evaluate how children process medicines? We share our methods for testing several medicines, and what matrices we use to do so. View the medicines we’ve studied and how, as well as request access to our methods, on our website:?https://lnkd.in/gqKB__ig
The Pediatric Trials Network
研究服务
Durham,North Carolina 194 位关注者
Making medicines safer and more effective for use in the youngest patients.
关于我们
The Pediatric Trials Network (PTN) is made up of over 100 clinical research sites studying the formulation, dosing, efficacy, and safety of drugs, as well as the development of medical devices, used in pediatric patients. Children are not simply “little adults” who respond to drugs according to scale. Rather, developing organs and changes in metabolism throughout infancy and childhood affect how drugs are processed by immature or maturing bodies. Thus, special care must be taken in tailoring the use of medicines in this unique and vulnerable population.
- 网站
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https://pediatrictrials.org/
The Pediatric Trials Network的外部链接
- 所属行业
- 研究服务
- 规模
- 51-200 人
- 总部
- Durham,North Carolina
- 类型
- 合营企业
地点
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主要
US,North Carolina,Durham
动态
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Data from #PTN studies have contributed to 23 FDA drug label changes. These label changes further our objective of improving dosing and treatments for children by adding information about use in pediatric patients. Read more about our research:?https://lnkd.in/e4SvzmQ2
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Are you a health care professional looking to get involved with the #PTN or #PediatricClinicalResearch? Check out PTN’s resources to submit a study concept proposal and browse training materials. https://lnkd.in/ec4pNWe7
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The #PTN publications library contains over 250 articles published in scientific journals. These articles are by faculty members involved with the PTN and highlight PTN’s study results.?Check them out:?https://lnkd.in/eFBPWa7C
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A new #PTN study is now enrolling! Guanfacine for Hyperactivity in Children with Down Syndrome (HYP01) is investigating the pharmacokinetics and safety of guanfacine for treating hyperactivity or ADHD in children with Down Syndrome. Learn more: https://lnkd.in/eh5UXcJM
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We partnered with iCAN (International Children's Advisory Network) to create an anthology of artistic works by their pediatric advocates. These works are inspired by their experiences and reflections on #PediatricClinicalResearch. Check out a digital copy:?https://lnkd.in/gaRgphcm
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This #PTN study investigated the most effective dose of #diazepam for treating severe seizures in children. Researchers used study data to develop a formula for weight-based dosage and update the label for diazepam. Read results-at-a-glance: https://lnkd.in/eJ9GiW_8
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The #PTN follows a prioritization list for research laid out by the Eunice Kennedy Shriver?National Institute of Child Health and Human Development (NICHD)’s Best Pharmaceuticals for Children Act (BPCA). Therapeutic areas include infectious disease, cardiovascular disease, respiratory disease, anesthetics, psychiatric disorders, and more. Read the full list: https://lnkd.in/gVJ-3uZq
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One way we help expand knowledge on #PediatricMedicine is by sharing data from completed and published studies with interested researchers. You can request access and view a list of available data at:?https://lnkd.in/d4q29CBn
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The #PTN’s research focuses on treatments that are often used for children but are understudied. Our research also emphasizes understudied, yet high-risk, groups like infants born prematurely and children with obesity. Read more: https://lnkd.in/eYWnXfnT