Regular sampling allows you to make informed adjustments and ensures optimal conditions throughout your cell culture process. 🔎 Join our Sr. Applications Engineer, Kenny C. for an expert-led detailed look at sampling completed in the 0.5L PBS Mini. SPOILER ALERT: Hydrodynamics at play! 🌊 🎥Watch the Full video here: https://hubs.li/Q02YBFLH0 #CellCutlure #Hydrodynamics #VerticalWheel
关于我们
PBS Biotech aims to be the leading provider of innovative, single-use bioreactor systems specifically designed to address the unique challenges of cultivating shear sensitive cell types for cell therapy development. Our offering includes scalable, cost-effective disposable solutions designed to take you from benchtop R&D to large-scale cGMP manufacturing, and expert process development services to help solve cell culture challenges and accelerate your path to commercialization. To learn more, contact our sales team at sales@pbsbiotech.com or visit our website at www.pbsbiotech.com
- 网站
-
http://www.pbsbiotech.com
PBS Biotech的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- Camarillo，California
- 类型
- 私人持股
- 创立
- 2008
- 领域
- Disposable bioreactors、Bioprocess solutions、Lab to cGMP cell culture development、USP Class VI plastics、cell therapy solutions、process development services、cGMP、iPSCs、MSCs、Pluripotent stem cells、Mesenchymal stem cells、stem cells、scale-up、3D cell culture、Single-use bioreactors、SUBs和process development
地点
-
主要
获取路线
4721 Calle Carga
US，California，Camarillo，93012
PBS Biotech员工
动态
-
💡 #Publication Spotlight! Seeking a breakthrough in iPSC expansion? We would like to spotlight this publication from the Stem Cell Research & Therapy journal- BMC. Transform your cell expansion protocol with revolutionary Vertical-Wheel technology in 3D cell culture! 🚀 Would like to learn more? Visit our website for the latest on our products and services. We look forward to connecting with you! 👉Read the full publication here: https://hubs.ly/Q02YrC-n0 #3D #CellExpansion #iPSC #VerticalWheelBioreactor
-
Excellent publication by Trailhead Biosystems describing a refined method for manufacturing functional #iPSC-derived β-cells using PBS Biotech Vertical-Wheel Bioreactors. Unlike traditional 2D protocols, this method enables optimal suspension culture conditions and #scalability required to serve as a potential source of #insulin-producing cells for the advancement of cell-replacement therapies for patients suffering with Type 1 #Diabetes Mellitus. #celltherapy #scaleup #verticalwheel
Excited to share our latest work on scalable #manufacturing of #iPSC-derived #insulin producing #βcells for Type 1 diabetes (T1D) treatment🌟 Type 1 diabetes, an autoimmune disorder requiring lifelong insulin therapy, has highlighted the need for innovative alternatives. Our research explores how iPSCs can provide a scalable source of functional β-cells, and we’ve made incredible progress toward optimizing this process. 🔬 What We Did - Explored critical bioreactor scale-up parameters using an advanced High Dimensional Design of Experiments (HD-DoE) protocol. - Implemented a three-stage suspension manufacturing process in 0.5L vertical wheel bioreactors, transitioning from adherent to scalable suspension culture. - Optimized stage times and nutrient profiles to improve differentiation and maturation of iPSC-derived islet-like clusters. 📈 Key Findings - Extended differentiation times and controlled lactate accumulation enhanced β-cell-like marker expression and function. - Cryopreserved aggregates retained viability and insulin secretion capacity post-recovery, demonstrating potential for storage and future transplantation therapies. - Continuous bioreactor runs showed promising metabolic shifts and differentiation profiles compared to traditional media change methods. This work represents a significant step forward in making scalable, cost effective, functional insulin-producing cells a reality. 🌟 A huge thank you to the amazing team at Trailhead Biosystems for their innovation and dedication in driving meaningful advancements in diabetes research and cell therapy! Special thanks to all co-authors: Alexandra Wells, Michael Majcher, Dhruv Nakhwa, Ryan King, Faruk Senturk, Dr. Roshan Padmanabhan, Jan Jensen, and PI Michael Bukys.
-
#PublicationSpotlight 💡 "Human pluripotent stem cells (PSCs) hold great promise for promoting regenerative medical therapies due to their ability to generate multiple mature cell types and for their high expansion potential." Topics covered in this publication include: ✔️ Effective 3D Differentiation ✔️ Consistency in Morphology and Cell Cycle profiles Read FULL publication here 👇: https://hubs.ly/Q02XPhfr0 #Microcarriers #iPSCs #3DSuspensionCulture
-
Did you miss our recent Webinar? No worries, the replay is now available! 👀 Key Highlights: ✔️Utilizing the wide operating window of the Vertical-Wheel Bioreactor family to enable effective scale-down model process development for linear scale-up. ✔️Demonstrating liner scale-up of PSC aggregate expansion from PBS 0.1L to PBS 80L scale to produce over 200 Billion PSCs from one bioreactor. 💡Want to learn more? Visit our website for the latest on our products and cell therapy resources! 👉 Rewatch Webinar here: https://hubs.li/Q02XQJBv0 #LinearScaleUp #VerticalWheel #CellExpansion
-
-
New Milestone Unlocked! 🔓 Join us in celebrating 300 installations of our PBS-3L Vertical-Wheel Bioreactor! 🎉 We are proud to reaffirm our commitment to our customers and remain dedicated to optimizing your cell therapy process through Vertical-Wheel technology. 👉To find out more about our Vertical-Wheel Bioreactor family, contact us here!: https://hubs.li/Q02Y0nkj0 #ScaleUp #VerticalWheel #Bioreactor
-
Ready to batch up and run those cells to achieve linear success? ✳️ Check out our latest video in the PBS Mini introductory series, where we dive deep into the batching process for a successful cell run! Watch Full Video Here 👇: https://hubs.ly/Q02XPTSY0 Need more information? 👀 Contact sales@pbsbiotech.com to discover how Vertical-Wheel technology can enhance your cell therapy process. #VerticalWheel #CellCulture #Batching
Batching in PBS Mini
https://www.youtube.com/
-
PBS Biotech转发了
We’re hiring! Check out this job at PBS Biotech: Bioprocess Research Associate - Intern
-
Imagine you just received your PBS Mini! 🎉 Check out the functions and features of the PBS Mini, plus a look at our Mini Vessels available in two sizes: 100 mL and 500 mL. To see what Vertical-Wheel technology can do for your cell therapy process, visit our website for more! 🎥 Watch full video here: https://hubs.ly/Q02XdSb_0 #VerticalWheel #Bioreactor #CellTherapy
Meet the PBS Mini: Vertical-Wheel Bioreactor
https://www.youtube.com/
-
Meet the PBS Mini! 🧫 This starting model to the Vertical-Wheel Bioreactor family offers superior homogeneous mixing of cell culture, available in 60-100mL working volume and 300-500mL working volumes! Whether you are just starting or looking to advance your cell therapy process from 2D to 3D, Vertical-Wheel technology is here to help. For a limited time, first-time customers based in the US can enjoy 20% off PBS Mini + Mini Vessels! 🔍 👉Don't wait, shop our beta e-Commerce site for more: https://bit.ly/48HrqCH