Nucleus Biologics

?? Exciting News??: Introducing NB-MSC? a cost-effective, serum-free, xeno-free media specifically designed for MSC culture. Part of the QuickStart Media? family, NB-MSC? delivers superior proliferation while maintaining the undifferentiated state for downstream development. Why Choose NB-MSC?? ? Superior Proliferation: Faster, more efficient MSC growth compared to DMEM + 10% FBS. ? Cost Savings: High-performance MSC kit at a lower price than other options. ? Consistent Performance: Batch-to-batch reliability ensures reproducibility. ? Reduced Contamination Risk: Xeno-, serum-free composition reduces risk from animal derived components. ? Regulatory Alignment: Simplifies the path from research to clinical applications. NB-MSC? includes basal media, coating solution, and supplement—all optimized to enhance MSC culture while reducing costs. Ready to elevate your MSC research? Read about it here and download interesting content: https://hubs.ly/Q02Z4v4b0 Connect with us today! #MSCs #CellTherapy #SerumFree #XenoFree #CostSavings #Innovation #LifeScience

Are you working with MSCs? Unlock their full potential with NB-MSC?, a serum-free, xeno-free media solution! Designed to enhance cell growth and ensure consistent, reproducible results, NB-MSC eliminates the variability and regulatory challenges of traditional FBS-based media. This optimized formulation supports the transition from research to clinical applications, offering a reliable and scalable solution for MSC proliferation. Take your MSC research to the next level with NB-MSC. See the data in our white paper: https://hubs.ly/Q02ZC1wN0 Explore the advantages of NB-MSC: https://hubs.ly/Q02ZC7sB0 #cellculture #msc #cellandgene

As Dr. Asma Ayari, Ph.D., our Head of R&D, explained in our recent webinar, you can unlock the potential of your cells with the right formula. At Nucleus Biologics, we understand that every therapy is unique—your cell culture media should be too. Our custom media and buffer solutions are designed to optimize cell growth, function, and gene expression, helping you accelerate cell and gene therapy development with precision and consistency. In case you missed it, catch the full webinar "The Formula for Success: How Custom Media and Buffers Support Cell and Gene Therapy Development" to learn how tailored solutions can transform your research and manufacturing process. ?? Watch here: https://hubs.ly/Q02YQsRT0 #CellTherapy #GeneTherapy #CustomMedia #CellCulture #Innovation #cellandgenetherapy #AAV #lentivirus

In cell therapy, delivering viable, functional cells to patients is paramount. Cryomedia plays a vital role in preserving cell health and functionality from production to administration, minimizing cell stress and maintaining potency during freezing, transport, and thawing. Optimized cryomedia helps to: ??Ensure Consistent Quality: Protecting cell viability and reducing apoptosis during freezing and thawing processes. ??Streamline Logistics: Enabling reliable long-term storage and simplifying transport. ??Enhance Clinical Outcomes: Supporting therapeutic effectiveness by preserving cells' critical properties. As cell therapy applications continue to expand, choosing the right cryomedia can be a game-changer for clinical and commercial success particularly in terms of quality and simplification of processes that may expedite your therapeutic developments. Download this whitepaper https://hubs.ly/Q02Y7Z710 to see how our DMSO-free cryomedia NB-KUL DF can help simplify your processes. #CellTherapy #Cryomedia #RegenerativeMedicine #Biotech #AAV #HEK #CART #cellandgenetherapy

?? Unlocking the Potential of iPSC Culture with FGF-2 TOP ?? ?? Why FGF-2 TOP? This innovative protein maintains high-quality #iPSC cultures, supporting #pluripotency and stemness across various concentrations and media feeding regimes. Recent data from Core Biogenesis and TreeFrog Therapeutics demonstrates its effectiveness: ??Flow cytometry data shows high expression of pluripotency markers under both 50 and 100 ng/mL FGF-2 TOP, in daily and every-other-day (EOD) feeding schedules. ??Impressively, EOD feeding with FGF-2 TOP achieves equivalent results to daily supplementation with traditional FGF-2, underscoring FGF-2 TOP's superior bioactivity and stability. Explore the full whitepaper for an in-depth look at how FGF-2 TOP can drive consistency in your iPSC cultures. https://hubs.ly/Q02X_6KG0 #StemCellResearch #iPSCCulture #BiotechInnovation #FGF2TOP #RegenerativeMedicine #celltherapy #cellandgenetherapy

?? Optimize Stem Cell Culture with a Cost-Effective, Sustainable, Thermostable FGF-2 ?? For stem cell researchers, finding the right balance between quality and cost efficiency is key. Our latest blog dives into how FGF-2 TOP? GMP, sustainably produced by Nucleus Biologics and in partnership with Core Biogenesis, delivers both. With high performance and consistency, this growth factor supports robust stem cell culture conditions—while also offering significant cost savings particularly at scale. Explore how you can reduce cost in your research - and for patients - without sacrificing quality, and learn about the sustainable, ultra-scalable processes that drive these advancements. Read more here: https://hubs.ly/Q02Xn3N80 #celltherapy #genetherapy #CostEffectiveResearch #StemCellCulture #SustainableBiotech #LifeSciences

Nucleus Biologics in partnership with Core Biogenesis is excited to announce the latest addition to our product lineup: FGF-2 TOP? GMP. This groundbreaking, plant-based, and eco-friendly solution is designed to revolutionize cell therapy. Our cutting-edge plant-based bioprocess, offers an ultra-scalable and cost-effective way to produce recombinant proteins. Thanks to the enhanced thermostability, you can enjoy 100% bioactivity with a remarkable 10-fold increase in half-life, meaning you’ll need less product without compromising on performance. What does this mean for you? More efficient, cost-effective stem cell development for both research and clinical applications. Why Choose FGF-2 TOP?? ??GMP quality ?? Cost-effective & ultra-scalable ??100% bioactivity preservation ?? Sustainable manufacturing ??10-fold improvement in half-life The full GMP product will launch in early 2025 but as of today you can order RUO samples to test in your processes! https://hubs.ly/Q02W_0qS0 Take advantage of our launch special – Buy One Get One through the month of November! Congrats to the development and launch teams at Nucleus and Core Alexandre Reeber David Sheehan Jordan Leff Chouaib MEZIADI #StemCellTherapy #CellTherapy #CellAndGeneTherapy #Biotech #Sustainability #GrowthFactor #stemcell #iPSC #MSC

???? We hope you had a spooktacular Halloween filled with treats, fun, and plenty of good cheer! ???? We had a fantastic time at our company party, celebrating the spirit of the season together. A big thank you to everyone who made it a memorable night! Wishing you a wonderful Fall season filled with treats, teamwork, and success! ?? #Halloween #CompanyCulture #TeamSpirit #FunAtWork #CellCulture #CellAndGene Nanami Kadota Asma Ayari Amber Longest Lauren Budde Jeffrey Tague Alexa Sabate Jody Bauer Zachary Hannan Fu'ad Rabi Nathalie Gaudefroy Ankita Chattaraj Pamela Garcia Michael Mendenhall Madeline Castillo October Pugliese Joey Chee

?? Exciting News! Join Nucleus Biologics' CEO, David Sheehan at Advancing Precision Medicine in Philadelphia this Friday and Saturday, Nov 1-2! David will be sharing insights in the session Optimizing Medium Formulation: Media Matters, delving into how custom media solutions can drive success in #celltherapy and #research. If you're attending, he would love to connect and discuss how our cell culture media, buffers, or reagents can meet your unique needs. Don't miss this opportunity to explore optimized solutions for your cell culture goals! Reach out to schedule a time to chat. #AdvancingPrecisionMedicine #CellCulture #MediaMatters #NucleusBiologics #PrecisionMedicine #genetherapy #cellandgenetherapy

?? A Faster Path to Custom Media for Your Cell or Gene Therapy: QuickStart Media! ?? ?? Customize or Use as Is: Tailor media formulations for your unique needs or leverage ready-to-use RUO options. ?? Expedited Path to GMP & Scalable Solutions: Quickly scale from the bench to the bioreactor with our high-quality solutions. ?? Proven Performance: Tested formulations for T cells, HEK cells, DMSO-free cryopreservation—and coming soon, MSCs! ?? Flexible Licensing Paths: Choose licensing options that free you from sole-source restrictions. Discover QuickStart’s transformative impact on media development in our blog: https://hubs.ly/Q02Wc2JY0 #CellTherapy #cellandgenetherapy # genetherapy #Biologics #MediaOptimization #ScalableSolutions #AAV #lentivirus