NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.
NewLimit的外部链接
US，California，South San Francisco，94080
NewLimit转发了
Early autumn update from NewLimit: - 0 → 70 TF sets tested in human hepatocytes via a chimeric human-animal liver system - +2779?TF sets tested in primary T cells - +51?TF sets that reverse the phenotypic age of T cells - 5 → 7?functional assays for hepatocyte age - 0 → 80%?efficiency for in-house LNP delivery to hepatocytes Check out our blog for all the details: https://lnkd.in/g4YPA6f2
We're #hiring a new Operations Specialist in South San Francisco, California. Apply today or share this post with your network.
We're #hiring a new Group Leader, Machine Learning in South San Francisco, California. Apply today or share this post with your network.
We're #hiring a new Group Leader, Functional Genomics in South San Francisco, California. Apply today or share this post with your network.
We're #hiring a new Head of Computational Sciences in South San Francisco, California. Apply today or share this post with your network.
Excited to share some updates from late summer at NewLimit. We've completed our first phenotypic to functional testing cycle and continued driving our Discovery Engine. A few highlights: - +2500 TF sets tested for their effect on cell age - +20 TF sets that reverse phenotypic age in T cells - 2X faster reprogramming library builds - 0 -> 3 hits with preliminary fxn effects in T cells - +3 fxn assays for hepatocyte age - +4 colleagues https://lnkd.in/gfXMBgtq
We're #hiring a new Scientist, Lipid Nano Particle Delivery in South San Francisco, California. Apply today or share this post with your network.
We're #hiring a new Senior/Research Associate, Functional Genomics in South San Francisco, California. Apply today or share this post with your network.
We're #hiring a new Scientist/Senior Scientist, Immunology in South San Francisco, California. Apply today or share this post with your network.
Updates from the early summer months at NewLimit: We reprogrammed old, human cells to look younger based on their genomic profiles. Now we need to make them act younger based on their function. We've made progress on building the tools to measure these functional improvments. Highlights by the numbers (quarter/quarter): - 2X lower cost per TF set we test - 1.5X the # of TF sets that reverse phenotypic age in real, human cells - +4 functional assays for hepatocytes, +1 for T cells - +3 team members All in our latest blog: https://lnkd.in/gT9bDDVb