National Cancer Institute (NCI)

Justin was diagnosed with a form of non-Hodgkin Lymphoma. After several treatments, including surgery, the cancer came back in a more aggressive form, and he felt like he was running out of options. Then, during a clinical trial at NIH Clinical Center (CC), Justin completed a new, 5-drug treatment called ViPOR. One year later after treatment, he returned to his job he loved at the National Park Service, and three years later the cancer has not come back. Read his story. https://go.nih.gov/WYeEz4z #NCIFuture #CancerResearch

Earlier this year, the U.S. FDA granted accelerated approval to tovorafenib (Ojemda) for kids and teens who have low-grade glioma with changes in the BRAF gene. In a small clinical trial, the drug shrank or completely eliminated tumors in nearly 70% of patients. https://go.nih.gov/VLZh0ZV #CCAM2024 Image Description: An MRI scan of a child with a low-grade glioma near the cerebellum. Credit: Pediatric Hematology Oncology Journal. June 2023. https://lnkd.in/emMhnbiV. CC BY-NC-ND 4.0 DEED

Hyperthermia is a type of treatment in which body tissue is heated up to 113 °F to damage and kill cancer cells. Although hyperthermia is not widely available, it is used at some centers along with other treatments such as radiation therapy and chemotherapy. Learn more: https://go.nih.gov/gBoLgK6 Media Description: An illustration of hyperthermia treatment. Image Credit: Therese Winslow

NCI-supported research is providing a clearer picture of how cancer affects the entire body. After decades of promoting collaborations and supporting progress in cancer biology research, NCI is poised to bring together research areas that contribute to our understanding of the effects of cancer on the entire body. Such knowledge is critical to inform proactive, personalized treatment plans for people with cancer. https://go.nih.gov/XHlsbVL #NCIFuture #CancerBiology

New research suggests that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – could potentially be used to enhance the effectiveness of immunotherapy. Read the NCI-supported study: https://go.nih.gov/uxGNcTn Image Credit: National Human Genome Research Institute (NHGRI)

More young adults are developing cancer than ever before. Worldwide, the rate of cancer among people between the ages of 18 and 49, known as early-onset cancer, has climbed by almost 80% since the 1990s. The reasons for the increase are not well understood, but NCI-supported researchers are investigating possible risk factors, such as the role of accelerated aging processes, pollution, and even microbes that live in the gut. With sustained funding, NCI is primed to develop interventions specific to early-onset cancers and the unique needs of this patient population. https://go.nih.gov/O1zvIqW #NCIFuture #CancerResearch

Researchers have discovered that dietary glutamine, an amino acid found in many foods, may be linked to the development of certain kinds of B-cell lymphomas in abdominal structures called mesenteric lymph nodes in mouse models. Learn more about this study from the NCI Center for Cancer Research. https://go.nih.gov/jNXsw4c Media Description: B cells migrate outside the center of the B cell follicle in mice without GNA13. Image provided by Jagan Muppidi, M.D., Ph.D.

Meet Leeya Pinder, an NCI-funded researcher who knew she wanted to be a doctor at age 7. Today, she is studying ways to prevent cervical cancer in low-resource areas in the United States and Zambia. Leeya looks forward to the day when multiple tools – such as artificial intelligence, immunotherapy, and vaccines -- establish a universal, affordable solution to prevent and treat cancer. “My goal is to try to heal the cervix so that this disease doesn’t progress to cervical cancer,” she explained. Read Leeya’s story. https://go.nih.gov/w91IJCu #NCIFuture #CancerMoonshot

Don't miss these exciting, upcoming events for cancer researchers, advocates, and community members! 1) Join us for the Childhood Cancer Data Initiative's webinar on September 10, 1:00 - 2:00 p.m. Register for “The Impact of the Molecular Characterization Initiative on Pediatric CNS Tumors.” Register now: https://go.nih.gov/RY8u9t4 2) The President's Cancer Panel is hosting two public meetings on September 12 and 13 around the topic of "Developing and Retaining a Robust and Diverse Cancer Workforce: Challenges and Opportunities Across the National Cancer Program." Find out more: https://go.nih.gov/g6bpk3c 3) The 15th Annual Childhood Cancer Caucus Summit, which raises awareness about childhood cancer research, will occur at Capitol Hill on Thursday, September 19, from 9:45 a.m. to 12:00 p.m. ET. This event is open to the public and will include NCI's Dr. Mary Frances Wedekind. Register for this event at https://go.nih.gov/WBroHj0

NCI enables advances against cancer by investing in a broad portfolio of research, supporting the #CancerResearch workforce, and sustaining the infrastructure that enables cutting-edge science to succeed. Learn how NCI drives discovery. https://go.nih.gov/tfms0NK #NCIFuture