Our CTO and cofounder Shashi Murthy will be presenting our recent work on "Machine Learning-Driven Design of mRNA Delivery Vehicles for In Vivo T Cell Therapies" (#299) at the Society for Immunotherapy of Cancer (SITC) 39th Annual Meeting on Friday, Nov 8th. ???????? In vivo versions of transformative cellular therapies offer the ability to dramatically simplify manufacturing complexity and cost, offering the potential to significantly enhance patient access. While proof-of-concept has been established for in vivo CAR-T, gaps remain in achieving efficient ex-hepatic delivery of nucleic acid payloads coupled with safety and efficacy. Additional benefits of in vivo approaches include the flexibility to re-dose and incorporate control elements such as on/off switches. This poster will describe the use of machine learning to discover novel polymeric delivery vehicles for mRNA delivery to human T cells, a collaborative effort by Nanite team members Aldo N., Nate Snell, Ph.D., Jeffrey Ting, Shannon Petersen, Jared Van Reet, Suteja Patil, & Teresa Tamayo. Please stop by Poster 299 to learn more! Link: https://lnkd.in/ei2mAFQN PDF: https://lnkd.in/eDHJ3_C6 #sitc24 #immunotherapy #CART #cancerresearch #genetherapy #nonviral #machinelearning
关于我们
Nanite is a next-generation non-viral gene delivery company developing a new class of programmable polymer nanoparticles for a range of modalities and indications. The company’s AI-driven platform, SAYER, combines cutting-edge high-throughput experimental and computational methods to design fit-for-purpose delivery vehicles delivering a broad range of genetic cargoes with tissue specificity.
- 网站
-
www.nanitebio.com
Nanite的外部链接
- 所属行业
- 生物技术研究
- 规模
- 11-50 人
- 总部
- Boston，MA
- 类型
- 私人持股
地点
-
主要
获取路线
451 D street
US，MA，Boston，02210
Nanite员工
动态
-
???? Halloween vibes are in full swing at Nanite! We’re celebrating with a spooktacular potluck— spine-chilling snacks, pizza, and costumes! ?? & ?? & ?? = 3 Our team knows how to bring the Halloween spirit! Wishing everyone a safe and fun celebration this spooky season! ???? #Halloween2024 #LifeAtNanite #SpookySeason #TeamCulture
-
-
Nanite转发了
I am thrilled to share that I have accepted my second co-op at Nanite! Thank you to Jake Walker for his support through the process and the Chemistry team for this opportunity. I look forward to starting in Janurary!
-
-
?? Fresh Gear for a Fresh Season! ?? We’re excited to introduce our new company quarter-zips-- perfect for staying comfy as we transition to fall in Boston! At Nanite, we’re not just pushing the boundaries of gene delivery, we’re also making sure our team stays stylish while doing it! ??????? #genetherapy #biotech #machinelearning
-
-
?? Meet us on the Mesa on today, October 7 at 11:45 AM MST at FLW Ballroom G! #CGMesa24 Our CEO & Co-founder Sean Kevlahan will discuss our company's goal in developing programmable, tissue-specific polymer nanoparticles (PNPs) for a broad range of modalities and indications ???????????? Add Nanite to your agenda here: https://lnkd.in/edEKvauM Alliance for Regenerative Medicine #nonviral #AI #machinelearning #genetherapy #biotech #CART #cysticfibrosis SalioGen Therapeutics Cystic Fibrosis Foundation Bill & Melinda Gates Foundation Arkitekt Ventures Zetta Venture Partners Dylan Reid Carl Schoellhammer
-
-
Delivery is a major challenge in genetic medicine, and while LNPs have played a key role, there's still much work to be done. We're proud to be at the forefront, developing polymer nanoparticles (PNPs) as delivery vehicles to help overcome this hurdle. Let’s keep the momentum going! ?? #GeneTherapy #Biotech #Innovation #DrugDelivery #Nanite
Delivery, delivery, delivery... Can Flagship solve the delivery hurdle? They have a new company to try. Mirai Bio was announced this morning to work on next-gen. LNPs. The company's leadership is also involved in Tessera, another Flagship company. https://lnkd.in/gDYtyt7z Genetic medicines have been, are, and will be, hampered by delivery. The LNPs of the pandemic saved the world, but hampered efforts into next-gen. delivery in a big way. Work on novel delivery vehicles and capabilities is only just starting to be revved back up again. I'm personally excited for these sorts of technologies along with other modalities like polymeric vehicles (e.g., Nanite). Let's see if we can crack the delivery nut. #genetherapy #biotech #venturecapital
-
-
Nanite转发了
?? Start Up Stories: Meet Shashi Murthy, CTO and Co-Founder of Nanite! ?? Nanite combines AI-driven polymer design with multiplexed in vivo screening to develop best-in-class nanoparticles engineered for tissue-specific delivery. Shashi will be joining us at Cell and Gene Therapy International this September 23-26 at the Hynes Convention Centre, Boston, USA. Find out more about Cell and Gene Therapy International here: https://lnkd.in/d9nmdak Learn more about their journey and impact! #Innovation #Startup #CellandGene
-
Nanite转发了
Both Teresa Tamayo and I had a wonderful American Chemical Society conference, learning new things and engaging with the polymers, biology, and computation communities. That’s it for #ACSFall2024! Nanite is heading home to Boston, until next time friends ????????????
-
-
Nothing beats a sweet midday break! ???? Earlier this afternoon, the team enjoyed a ginormous *Cookie Monstah* over lunch, courtesy of the Related Beal 451D Street management company. Moments like these fuel our passion and drive to define future of genetic drug delivery-- let's keep the momentum going! ????
-
-
As a member of the American Chemical Society POLY Industrial Advisory Board, we're proud to support this new symposium at #ACSFall2024 next week, which showcases the exciting developments on AI, data science, and automation across the global polymer industry. This event promises to be an inspiring day filled with insights for professionals and students alike! If you are interested in our recent work in next generation non-viral delivery, feel free to reach out to our terrific scientists Teresa Tamayo & Jeffrey Ting. Both will be attending the conference and available to chat! ??????????
The #ACSFall2024 Meeting is < 1 week away, and members of the Division of Polymer Chemistry Industrial Advisory Board (POLY IAB) are proud to host a new session in Denver on "Elevating the Power of Data for Materials and Chemical Scientists in Industry" next Wednesday, Aug 21 at the Grand Ballroom in the Sheraton Denver! We have assembled a diverse group of invited speakers to discuss their experiences solving real industrial problems using data-driven methods and related digital tools. Talks are listed below, ranging from data management, machine learning, AI, software automation, hardware automation, high-throughput experimentation and simulation, and other digital tools ?? ? ? Special thanks to Nanite, Alix Schmidt of Dow, and Michael Heiber of Enthought for co-organizing this new symposium with support from Enthought, POLY, PMSE, and CINF. Please help us distribute this flyer to any colleagues or students attending the national meeting to help build this growing community in industry, academia, government, and national labs ??
-