Mozart Therapeutics, Inc.

We are thrilled to announce our first peer-reviewed publication! The manuscript, appearing in Frontiers in Immunology, highlights our preclinical data with MTX-101, a novel autoimmune checkpoint inhibitor. We’re incredibly proud of our team who generated data showing that MTX-101 can restore CD8 Treg cytolytic killing of pathogenic CD4 T cells, key drivers in the pathogenesis of autoimmune disease. Read the manuscript here: https://lnkd.in/gWGXZEmB

It’s a busy week here at Mozart, with two presentations at leading scientific and medical conferences. ? Today, Catherine McMahan is in San Francisco at the 24th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS). Stop by the Exhibit and Poster session this evening (June 19th)—6:15 to 7:30pm Pacific—to learn more about the nonclinical development of MTX-101, our novel CD8 Treg modulator [poster W114; see it here: https://lnkd.in/gCHuETSR] Additionally, we are thrilled that our preclinical data on MTX-101, supporting development of this autoimmune checkpoint inhibitor for the treatment of type 1 diabetes, was selected for oral presentation at the 2024 American Diabetes Association 84th Scientific Sessions in Orlando, FL. ADA attendees can catch the presentation by Courtney Crane on June 21 at 3:15pm Eastern [IBC-ORO1-1.5, Room W304 A-D]. #FOCIS2024 #ADA2024 #IMMUNOLOGY

I'm super excited that Mozart has become a clinical-stage company, and so grateful for the participants who are helping us evaluate this novel therapeutic!

We’re pleased to announce that clinical development is underway for MTX?101, our novel autoimmune checkpoint inhibitor! The Phase 1a/b clinical study is ongoing in healthy adults, and plans to include patients with celiac disease and type 1 diabetes. This significant milestone brings us closer to our goal of changing the treatment paradigm for those affected by autoimmune diseases. https://lnkd.in/gxnazZqg

This week marks the 6th Annual Treg-Directed Therapies Summit, held May 21-23 in Boston. We’re honored to have our Chief Scientific Officer, Kristine Swiderek, leading the discussion on the therapeutic potential of modulating CD8 Treg for the treatment of autoimmune disease, including Mozart’s own novel autoimmune checkpoint inhibitor, MTX-101. https://lnkd.in/evaCdwM

We’re excited to be attending this year’s IMMUNOLOGY2024 meeting in Chicago, Illinois.? Come by the poster session on May 6 where we’ll be presenting new data on our KIRxICOS CD8 Treg modulator. Read more: https://lnkd.in/gbyyAser ?#AAI2024??#Immunology.