Mount Sinai Division of Gastroenterology

A research team led by Mount Sinai has uncovered mechanisms of abnormal #ImmuneCell function that may lead to #CrohnsDisease, as published in #ScienceImmunology. Their discovery could pave the way for new #Therapeutics to prevent inflammation before it starts. Learn how gamma delta IELs play a critical role in maintaining immune balance and how their early loss may trigger disease onset. This research could help predict #IBD relapse and improve treatment strategies. Learn more: https://bit.ly/4iGxY96 Mount Sinai Department of Medicine #Gastroenterology #InflammationScience #PrecisionMedicine Karen Edelblum

Join us on Wednesday, March 26, 2025, from 9 AM to 3 PM to learn about your colon health, speak with an expert, and get your screening questions answered. For screening options or referrals, call Mount Sinai’s CHOICE Program at 212-824-7887. #WeFindAWay #ColorectalCancerAwarenessMonth #ColorectalCancer Mount Sinai Department of Medicine The Mount Sinai Hospital

Congratulations to Brijen Shah MD on his election into the American Gastroenterological Association (AGA) governing board as Education & Training Councillor. Dr. Shah has dedicated his career to shaping the future of #gastroenterology through his #leadership in #fellowship training, competency-based medical education, and patient safety. As an Associate Dean for GME at Icahn School of Medicine at Mount Sinai and a former Associate GI Fellowship Director, he has played a pivotal role in mentoring rising #GIs and advancing medical education. His impact extends globally as he collaborates on safety and quality initiatives worldwide. AGA is fortunate to have his visionary leadership. We're all excited to see his continued impact in this well-deserved, new role.

March is Colorectal Cancer Awareness Month. Did you know that the recommended screening age for colorectal cancer is now 45? Early detection saves lives! In our latest video, Dr. Michael Smith explains why screening is crucial—especially as more young adults are being diagnosed with large polyps or cancer. Don’t wait—get screened. Plus, stop by our tabling events this March to learn more and ask questions. ?? Upcoming Events: March 4 – Mount Sinai Queens - Pavillion Lobby March 6 – Mount Sinai-Jackson Heights March 11 – Mount Sinai West - Main Lobby March 13 – Mount Sinai-Union Square - 2nd Floor Green space March 18 – Mount Sinai Morningside - Ambulatory Care Center Lobby March 20 – Mount Sinai Brooklyn - Main Lobby March 26 – The Mount Sinai Hospital - Guggenheim Pavillion Lobby #ColorectalCancerAwareness #GetScreened #MountSinai #ColonHealth #EarlyDetectionSavesLives Mount Sinai Health System The Mount Sinai Hospital Mount Sinai Morningside Mount Sinai West Mount Sinai Queens Mount Sinai Division of Gastroenterology

The 20th Annual #MountSinai IBD Consultant's Course brought together leading experts and clinicians for an in-depth exploration of the latest advancements in #IBD care. From ground-breaking therapies to real-world clinical strategies, attendees gained invaluable insights for enhancing patient outcomes. Looking forward to next year's course! #IBD #CME #inflammatoryboweldisease #ulcerativecolities #crohnsdisease #colitis #crohns #wefindaway

March is Colorectal Cancer Awareness Month. Mount Sinai is hosting several educational events at various locations across the System from 9 am - 3 pm. Gain insights into your colon health, speak with an expert, and have your screening questions answered by the care team. Don't miss this chance to take charge of your health and prevent colorectal cancer. To discuss your screening options or if you have a referral, call Mount Sinai's CHOICE Program at 212-824-7887. #NYC #ColorectalCancerAwareness #ColonHealth #ColonCancerPrevention #WeFindAWay Mount Sinai Division of Gastroenterology Icahn School of Medicine at Mount Sinai Mount Sinai Health System The Mount Sinai Hospital Mount Sinai West Mount Sinai Hospital - Brooklyn Heights Mount Sinai Queens Mount Sinai Morningside

The Cohen Laboratory at the Icahn School of Medicine recently published their work entitled “Reparative immunological consequences of stem cell transplantation as a cellular therapy for refractory Crohn’s disease” in the journal GUT: https://bit.ly/41Ip7O9 . Patients with Crohn’s disease that failed to respond to traditional medications or surgery underwent an autologous stem cell transplant with over 90% of patients demonstrating at least partial healing of their intestine. Patients provided samples throughout the stem cell transplant process to help investigators understand the therapeutic mechanisms of stem cell transplantation and how hematopoietic stem cells can be used to restore a healthy immune system. The results of these studies suggested stem cell transplant restored healthy intestinal macrophages needed to support intestinal healing which may be defective in medically refractory Crohn’s disease. Interestingly, this study suggests Crohn’s disease may impair hematopoietic stem cells suggesting an entirely new pathophysiology relevant to the development of Crohn’s disease therapies and diagnostics. This work was accomplished through a multidisciplinary collaboration at Mount Sinai including the Feinstein Inflammatory Bowel Disease Center and the Tisch Cancer Institute. Physicians, scientists and patients interested in learning more about this innovative clinical research program for patients with medically refractory Crohn’s disease can visit https://bit.ly/41vYSKx Mount Sinai Department of Medicine Icahn School of Medicine at Mount Sinai Louis Cohen

It was wonderful to present a plenary talk about the initial outcomes from the International Crohn's Disease Stem Cell Transplant Consortium at ECCO European Crohn' and Colitis Organisation meeting in Berlin. We will continue our work to understand the long-term clinical outcomes of stem cell transplant and to create standardized clinical protocols for patients with Crohn's disease. This work could never have been done without an incredible collaboration between physicians and scientists at Mount Sinai Division of Gastroenterology (Jean-Frederic Colombel, Daniela Guisado), Hospital Clínic de Barcelona (Azucena Salas, Elena Ricart), Queen Mary University of London (James Lindsay), and UMC Utrecht (Bas Oldenburg, Herma Fidder).

A breakthrough in ulcerative colitis treatment! Mount Sinai-led research shows that tulisokibart, a first-in-class monoclonal antibody, is safe and effective in helping patients who haven’t responded to other therapies. Learn how this novel approach could change the future of IBD care. Read more in the 2025 Gastroenterology and GI Surgery Specialty Report: https://mshs.co/40UJGGy #UlcerativeColitis #IBDTreatment #Breakthrough

For women with IBD, family planning can come with uncertainty. Mount Sinai’s new WIsDoM study aims to change that by providing high-quality data on how surgery, medications, and disease activity impact #fertility. Learn how this groundbreaking research is shaping the future of #IBD care: https://mshs.co/4hdvwWT