Molecular Instruments

We have exciting news to share! Molecular Instruments has won the UK lawsuit brought by Advanced Cell Diagnostics (a Bio-Techne group company), with the Court finding that two patents owned by Advanced Cell Diagnostics are invalid on obviousness grounds. Please see the press release linked below for more details. We look forward to continuing our mission to provide game-changing #onlywithHCR reagents to biologists, bioengineers, drug developers, and diagnostics developers worldwide. To learn more about our HCR??imaging platform, check out our Automated Products (www.hcrimaging.com) and our Manual Products (https://lnkd.in/gJZePKk). https://lnkd.in/g_WfxEjF

?? As we take a moment to express our gratitude, we want to thank our amazing partners and users. Your trust and collaboration continue to inspire us at Molecular Instruments as we work together to drive scientific progress. Thank you for choosing the HCR? platform to explore new frontiers in your groundbreaking research. Your discoveries are what fuel our commitment to delivering the best tools for advancing science. We are excited for what’s ahead and look forward to continuing our partnership to push the boundaries of innovation and discovery! ??

In a recent interview with John Manuel, PA(ASCP) from Spatial Bio Hub, our Chief Commercial Officer,?Aneesh Acharya, PhD, shared how Molecular Instruments is transforming RNA imaging with the HCR? platform by making RNA imaging faster, more reliable, and more affordable—across both research and clinical applications. Aneesh emphasizes that, “By avoiding protease steps and heavy tissue digestion that other methods require, we've built a system that's both efficient and reliable.” Take a deeper dive into the interview here:? https://lnkd.in/gvrvQQB9

Looking for your next travel destination? ?? ???#MIRecommends: Bali, Indonesia We are kicking off our Monday strong with a Molecular Instruments' travel recommendation to Bali, from Randy Chen, our Director of Research and Development. He describes the Indonesian province as, "a good place for relaxation, cultural experience, and even holding wedding ceremonies without breaking one's wallet!"

Groundbreaking Advancement in Whole Brain Imaging!??? We're excited to celebrate a major milestone in neuroscience research, led by Shigeaki Kanatani and Per Uhlén from Karolinska Institutet. Their pioneering work has made it possible to visualize RNA gene expression in intact rodent brains, marking a huge leap forward for the field. At Molecular Instruments, we're proud to have played a role in this achievement by providing our HCR? Imaging technology to enable this cutting-edge 3D brain imaging. This breakthrough opens up new opportunities for understanding brain function and advancing research on neurodegeneration and the central nervous system (CNS). A huge congratulations to the entire team for not only developing and publishing this groundbreaking work,?but also for landing the cover of Science Magazine! We're thrilled to see our partners develop innovative workflows that make discoveries like this possible #onlywithHCR. Read more about this exciting development here:?https://lnkd.in/dE3G7PbE

#OnlyWithHCR User Spotlight We’re thrilled to feature Kiichi Watanabe, Hui (Vivian) Chiu, and David J. Anderson for their groundbreaking work using HCR? RNA-FISH technology. Their study,?"HI-FISH: Whole brain in situ mapping of neuronal activation in Drosophila during social behaviors and optogenetic stimulation," demonstrates how the HCR? RNA-FISH method enabled the detection of brain-wide expression of Hr38 and neuronal activation during complex behaviors like aggression and courtship. This innovative research showcases the power of #HCRtechnology to advance neuroscience! Learn more:?https://lnkd.in/gGPdfdM7

Great to see James R. Mansfield at #SITC2024 highlighting the power of combining Visiopharm's Oncotopix Discovery?software?with our HCR? Pro RNA-ISH assays for enhanced RNA detection and accuracy in?RNA quantification! Check out our joint poster here: https://lnkd.in/g5gNCy_E

Hidden gem with fresh seafood and scenic views? Say less! ??? #MIRecommends: The Jolly Oyster On this week's edition of Molecular Instruments' Recommends, Adam Maddox, PhD, one of our Research Scientists, recommends The Jolly Oyster at the State Beach in Ventura, California. Alongside being an interactive experience, Adam shares, "My wife and I got engaged at this beach, so it also holds a special place in our hearts." Fun Fact: Oysters have been used in #researchstudies due to the bioactive compounds in their tissues and cells and their potential use in #biomedical research! If you're looking for your next weekend activity, check out The Jolly Oyster! ??

On this week's installment of our #onlywithHCR series, we're highlighting Williams et al. and their work that was able to depict the overlap with the neural crest market gene expression and the Chd7 enhancer activity. Using #HCRimaging, they found that, "despite its broad expression during early chick embryo development, the chromatin remodeller Chd7, is upregulated in the neural crest by tissue specific enhancers." Check out Ruth Williams, Tatjana Sauka-Spengler, Güne? Taylor, Irving Ling, Ivan Candido-Ferrerira, Sarah Mayes, and Julianna O. Haug's paper here: https://lnkd.in/g7VaRtfq

What an incredible weekend at Society for Immunotherapy of Cancer (SITC)! Our team at Molecular Instruments was thrilled to connect with leading experts, researchers, and innovators in the field of cancer immunotherapy. This year our presence at #SITC2024 was one for the books—thank you to everyone who stopped by our booth, shared their insights, and engaged in discussion! We’re excited to contribute to driving innovation in the fight against cancer. If you didn't get a chance, check out our posters with Visiopharm, Indica Labs, Bruker, and Navinci here: https://lnkd.in/g5gNCy_E