Molecular Assemblies, Inc.

A Heartfelt Thank You to Our Team It is with a heavy heart that we report the difficult decisions we have had to make regarding Molecular Assemblies. Despite our team's tireless efforts and significant technological achievements, we find ourselves evaluating the best path forward to allow this important technology to be further developed which has led to the decision to terminate many of our employees. The past few years have been both inspiring and humbling. We built groundbreaking technologies and assembled an extraordinary team of talented professionals who have poured their hearts and souls into our mission. Our technology works, and it works well. However, as we began our commercial launch, we encountered an unprecedented and challenging financial funding market for tools companies that has proved insurmountable given our cash runway. Simply put, we ran out of time. An immediate priority is supporting our outstanding team members as they transition to new opportunities. We are actively asking our network to connect our associates with companies that will benefit from their exceptional skills and dedication. These individuals represent some of the finest talent in our industry, and we are confident they will continue to make remarkable contributions wherever their careers take them. To our investors, customers, and partners, thank you for trusting us to support your important work. Your belief in our mission has been our greatest motivator, and we are proud to have contributed to advancing science alongside you. To our team, you are the heart and soul of Molecular Assemblies. Your passion, creativity, and relentless dedication have been nothing short of inspiring. While this chapter is closing, the incredible work you’ve accomplished will have a lasting impact as we explore strategic alternatives. We want to acknowledge and celebrate the contributions of everyone who helped build this company and support our vision. For those companies seeking exceptional talent, our team members are truly extraordinary, and we encourage you to connect with them as they pursue their next opportunities. https://lnkd.in/gEUehsEE

“Unlike traditional chemical synthesis, FES can build long and accurate sequences regardless of complexity, enabling the reliable construction of the most difficult sequences”? ? Recent read on GEN News. Find out more about how our FES technology is enabling the reliable synthesis of ITRs, Poly A tails, and secondary structures.? ? https://lnkd.in/gaqtUGuk #EnzymaticSynthesis #FES #DNA #DNAuncompromised #DNAsynthesis #syntheticbiology #oligos #synbio #oligonucleotides

Please join our webinar on Nov 19th featuring Konlin Shen, PhD of UCSF’s Douglas Lab and our very own Director of Scientific Innovation Natasha Paul, PhD. Konlin will be discussing applications of our Fully Enzymatic Synthesis (FES) technology in DNA nanotechnology. His research studies the mechanism of complex genetic construct replication by phage using long randomer sequences limited by chemical synthesis capabilities. Learn more about how our FES technology enables researchers to advance their research uncompromised:? https://lnkd.in/gv8tehyk Save the date and watch live to join the Q&A for key insights from Natasha and Konlin. #EnzymaticSynthesis #FES #DNA #DNAuncompromised #DNAsynthesis?#DNAnanotechnology #syntheticbiology #oligos #synbio #oligonucleotides

Welcome Felice Butler to the MAI team as Key Account Manager! She will play a pivotal role as we advance our #FES #DNAsynthesis to new researchers to power the future of #synbio. ?Our fully enzymatic platform synthesizes highly accurate 400nt oligos?with no post process purification or complexity screeners necessary! ? ? If you are in the Pacific Northwest region, Felice is ready to answer questions on how our #enzymaticDNAsynthesis can accelerate your research and therapeutic development: https://lnkd.in/gpnmZX_Q ? #DNAuncompromised #DNA #synthesis #enzyme #CRISPR #CGT #geneediting #precisionmedicine #lifesciences #syntheticbiology #biotechnology #biology #science #technology #oligos #oligonucleotides #geneediting?

As we continue to increase the length of our oligos, the critical importance of understanding and preventing biosecurity risks cannot be ignored. Molecular Assemblies understands our responsibility, and as a member of the International Gene Synthesis Consortium we adhere to the Harmonized Screening Protocol to ensure our services can maximize your research while minimizing any risks of misuse.? The ever-expanding benefits of advancing synthetic biology technologies cannot be understated, but we must be vigilant of the biosecurity risks that could jeopardize the harmony of our industry.? Find our commitment as well as key resources to learn more about good screening practices for?DNA Synthesis: https://lnkd.in/gASi6w6D ?

Molecular Assemblies has partnered with Steve Bischoff, CSO and Cofounder of NovoHelix for their human pluripotent stem cell engineering, and we are excited to share the results!? NovoHelix achieved a breakthrough in knock-in efficiency using MAI’s high purity ssODN donors. With longer lengths, higher purity, as well as the ability to synthesize more complex elements, MAI’s Fully Enzymatic Synthesis alleviates many design challenges to enable more advanced genome engineering. Explore how precision in DNA oligonucleotides can transform your CRISPR Research: https://lnkd.in/gdhch99v #CRISPR #geneediting #genetherapy #synbio #syntheticbiology #DNA #oligos #oligonucleotides #EnzymaticSynthesis #FES #DNAuncompromised #DNAsynthesis??

"Molecular Assemblies became the first to enable the synthesis of oligos over 200 nucleotides, lengths that are unattainable with chemical synthesis." Read more in the recent article from SynBioBeta highlighting our journey and the impacts our long oligos are making in the synbio space. https://lnkd.in/gz4SE3tj #synbio #syntheticbiology #oligos #oligonucleotides #EnzymaticSynthesis #FES #CRISPR #geneediting #genetherapy #DNA #DNAuncompromised #DNAsynthesis

Happy Manufacturing Day ?? As we scale up production and bring our oligos to new customers, we are proud to showcase the talent and dedication of MAI’s?production team. It is our manufacturing team who are consistently putting in the work to get your long oligos reliably. Their commitment fuels our uncompromising mission to unlock the potential of your research ambitions. Check out our industry leading oligos?(brought to you by our manufacturing team) and see how?longer, purer, and more complex oligos can empower your research: https://lnkd.in/gpnmZX_Q #MFGday #MFG #Manufacturing #ManufacturingDay #Biotech #Synbio?

Secondary Structures creating a roadblock in your #synbio research? Secondary Structures have been a barrier for many researchers when ordering DNA, despite these structures being necessary in gene regulation and gene functionality. With the need for more complex DNA for Gene Synthesis, DNA Origami, and IVT templates, compromising your sequences due to complexity screeners can no longer be the default.? Discover why chemical DNA synthesis has struggled to make secondary structures and how Enzymatic DNA Synthesis may help you get the DNA you need. ??: https://lnkd.in/gjw2hCjc #DNAuncompromised #FES #SecondaryStructures #DNAsynthesis #science #biotech #oligos #oligonucleotides #lncRNA #mRNA #RNA #DNA #IVT #DNAOrigami #syntheticbiology #genetherapy #geneediting #AAV #CRISPR

Welcome Ronan Bates to the MAI team as our new Marketing Associate!?As we continue to expand commercially, we are confident Ronan will play a pivotal role in spreading awareness for our novel Fully Enzymatic Synthesis technology and communicating new ways to use our long oligos.? ? Find out how MAI can accelerate your #synbio research: https://lnkd.in/gpnmZX_Q?? ?? #DNAuncompromised #FES #DNAsynthesis #DNA #synthesis #enzyme #CRISPR #CGT #geneediting #precisionmedicine #lifesciences #syntheticbiology #biotechnology #biology #science #technology #oligos #oligonucleotides #geneediting?