Melior Discovery Inc (Exton, PA, USA) has pioneered a unique “high throughput” in vivo pharmacology platform (theraTRACE?) able to systematically identify novel indications for pre-clinical and development stage drugs. theraTRACE? is widely used by both multinational pharmaceutical and start-up biopharmaceutical companies alike to fully explore the therapeutic potential of their drug candidates. Melior has also leveraged this expertise to build a high quality, onshore, preclinical services capability offering in vivo efficacy models in a broad range of therapeutic areas, pharmacokinetic evaluations, specialized animal models and bioanalytical services to drug developers worldwide.
Melior Discovery的外部链接
860 Springdale Drive
US，PA，Exton，19341
Congratulations, Rectify!
Today, we announced the selection of our lead ABCB4/BSEP dual-targeted positive functional modulator (#PFM) for treatment of primary sclerosing cholangitis (PSC) and a broad range of hepatobiliary diseases by improving bile composition and enhancing bile flow. We look forward to advancing RTY-694 a novel, differentiated, oral small molecule to first-in-human clinical trials for PSC. Read our press release to learn more: https://bit.ly/48jIezp
Researchers have determined mouse prepulse inhibition (PPI) genes significantly align with human Schizophrenia risk genes. This knowledge can be used to help identify druggable targets in Schizophrenia and emphasizes that rodent models can sufficiently represent critical aspects of Schizophrenia's pathology. https://lnkd.in/gX6UnRPE
Scientists at the University of Texas Health Science Center at San Antonio have created the first humanized mouse model with a functional human immune system and human-like gut microbiome: https://lnkd.in/guV98agf
Check out this interesting article suggesting kidney damage and dysfunction may make traveling to Mars a bigger reach than expected: https://lnkd.in/gmqBSYik
Did you know that Melior participates in Scientist.com and Science Exchange platforms? These online marketplaces can help streamline your project from start to finish!