It’s great to see innovative companies looking to reduce the time it takes to synthesize new IVT templates. We believe these next generation approaches coupled with a cell-free DNA scaleup technology such as our LineaDNA? platform greatly reduces mRNA manufacturing timelines to support equitable access to life saving treatments. #EnzymaticDNAProduction #PCR #mRNA #NucleicAcidBasedTherapies #CellFreeDNAProduction
LineaRx, Inc.
生物技术研究
Stony Brook，NY 372 位关注者
The enzymatically-produced alternative to plasmid DNA
关于我们
LineaRx, Inc. (an Applied DNA Sciences, Inc. (NASDAQ: APDN) company) delivers enzymatically produced LinearDNA? as an alternative to current plasmid-based DNA manufacturing processes with advantages of speed, purity, and scalability to support the next generation of nucleic acid-based therapies. Manufactured by a proprietary, large-scale polymerase chain reaction (‘PCR’)-based manufacturing platform, LinearDNA allows for the rapid and efficient cell-free production of high-fidelity DNA sequences. LinearDNA is relevant to a broad array of advanced therapeutics, including mRNA production, DNA vaccines, cell and gene therapies, as well as numerous veterinary medicine applications. Formed in 2018 to commercialize our parent company’s 20+ years of experience and leadership in enzymatic DNA production, LinearRx stands ready to deliver a new generation of DNA for the next generation of medicines. LineaRx, We are DNA Made Simple.
- 网站
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https://www.linearxdna.com/
LineaRx, Inc.的外部链接
- 所属行业
- 生物技术研究
- 规模
- 2-10 人
- 总部
- Stony Brook，NY
- 类型
- 上市公司
- 领域
- Biotherapeutics、Linear DNA和DNA Vaccines
地点
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主要
获取路线
US，NY，Stony Brook，11790
LineaRx, Inc.员工
动态
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LineaRx, Inc., an Applied DNA Sciences company, and Kudo Biotechnology, introduce a new and novel platform for rapid mRNA production under GMP that utilizes a cell-free enzymatic process to replace the industry's traditional use of pDNA. Linea? DNA, a linear dsDNA template, can replace pDNA to significantly accelerate the production of high-quality mRNA therapeutics. When used in combination with a proprietary RNA polymerase (Linea? RNAP), Linea DNA further minimizes dsRNA impurities and unwanted immune responses endemic to conventional mRNA production workflows. #mRNAtherapeutics #pDNA #GMP ? Read the white paper here (registration required): https://lnkd.in/gQdctSQA
Kudo Biotechnology?and?LineaRx?present: ?WHITE PAPER – "Fast-tracking mRNA Medicines: A synthetic DNA platform to optimize mRNA production" We introduce a streamlined, flexible process for mRNA therapeutic production that eliminates traditional pDNA steps. Using cell-free enzymatic production from our partner LineaRx on the Kudo Bio platform, we enable faster, cost-effective, and scalable cGMP manufacturing of high-quality mRNA. The white paper also highlights LineaRx’s proprietary RNA polymerase, which, when combined with the linear dsDNA template, minimizes dsRNA impurities for an added advantage. Download the white paper here https://lnkd.in/g4rSvWdK
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Applied DNA Sciences announced the completion of the buildout of its new Good Manufacturing Practices (GMP) manufacturing facility within its Stony Brook, NY headquarters and readiness to accept orders for the manufacture of LineaDNA? IVT templates that clients can utilize for the production of mRNA clinical trial materials. The facility is undergoing final testing and is expected to be fully operational by the end of the current month. The Company is?actively negotiating a supply agreement for GMP IVT template with a mRNA therapeutic developer. #syntheticbiology #EnzymaticDNAProduction #PCR #mRNA #GeneticMedicine #NucleicAcidBasedTherapies #DNAInnovation #CellFreeDNAProduction #SyntheticDNA #BiotechInnovation
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LineaRx, Inc.?will be attending the 43rd Annual J.P. Morgan Healthcare Conference, taking place January 13-16! Schedule an appointment with?Clay Shorrock?to learn about how our scalable GMP enzymatic DNA manufacturing services can empower the next generation of genetic medicines. #JPM2025 #mRNA #CancerVaccine #PersonalizedCancerVaccine #vaccine #PersonalizedMedicine
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Executive Director, Investor Relations and Corporate Communications, Applied DNA Sciences, Inc. (NASDAQ: APDN)
Our GMP space is coming along! $APDN #geneticmedicine #syntheticDNA #syntheticbiology #EnzymaticDNAProduction #PCR #mRNA #NucleicAcidBasedTherapies #DNAInnovation #CellFreeDNAProduction #BiotechInnovation #GMP
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The State Institute for Drug Control of the Czech Republic (SúKL) approved an application for a Phase I clinical trial of an investigational CD123-specific autologous CAR T-cell therapy by the Institute of Hematology and Blood Transfusion (úHKT/Eng:?IHBT) in Prague for the treatment of relapsed and/or refractory acute myeloid leukemia (AML). UHKT-CAR123-01 utilizes Applied DNA’s synthetic DNA, Linea? DNA, as a critical component in its manufacture. #GeneticMedicines #CAR-T #CARtherapies #syntheticDNA #AML #KnowAML #acutemyeloidleukemia
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Clay Shorrock and Aaron Chung are all smiles on the final day of the 2024 Personalized Cancer Vaccine Summit in Boston! Contact us to learn more about our scalable biomanufacturing services for personalized DNA/RNA vaccines and therapeutics. #mRNA #CancerVaccine #PersonalizedCancerVaccine #vaccine #PersonalizedMedicine
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LineaRx, Inc. is back in Boston this week at the 2024 Personalized Cancer Vaccine Summit, starting today through December 5.?Meet with Clay Shorrock and Aaron Chung to learn about our scalable biomanufacturing services for personalized DNA/RNA vaccines and therapeutics. #mRNA #CancerVaccine #PersonalizedCancerVaccine #vaccine #PersonalizedMedicine
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This week Applied DNA Sciences will be participating in the 3rd Annual mRNA Process Development & Manufacturing Summit and will co-host seminar with mRNA CDMO Kudo Biotechnology. #syntheticbiology #EnzymaticDNAProduction #PCR #mRNA #GeneticMedicine #NucleicAcidBasedTherapies #DNAInnovation #CellFreeDNAProduction #SyntheticDNA #BiotechInnovation Aaron Chung Clay Shorrock Atsuko Sakurai-Sangria
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Applied DNA Sciences has received a follow-on order valued at more than $500,000 for a quantity of Linea? DNA from a global manufacturer of?in vitro?diagnostics (IVDs). #syntheticbiology #EnzymaticDNAProduction #PCR #mRNA #GeneticMedicine #NucleicAcidBasedTherapies #DNAInnovation #CellFreeDNAProduction #SyntheticDNA #BiotechInnovation