Keto-Mojo

The evidence shows that patients who receive instant feedback on their dietary choices have higher rates of compliance. That's why real-time monitoring of patient health data can be a game-changer for health practitioners who, in the past, have had to rely on the memory and honesty of patients in reporting compliance with their treatment programs. With MyMojoHealth, practitioners can quickly scan their patient's blood glucose and ketone readings on a daily or weekly basis and identify the patients that need more attention. Learn more about the free MyMojoHealth platform for healthcare practitioners here: https://lnkd.in/ghUcjDcT #keto #ketomojo #healthcare #remotepatientmonitoring https://lnkd.in/gVNr-3CK

Can ketone bodies help clear misfolded proteins linked to neurodegenerative diseases? A new study suggests that β-hydroxybutyrate (βHB)—a key ketone body—plays a direct role in protein clearance and brain health. Key findings: → βHB selectively targets misfolded proteins, including amyloid-β, a hallmark of Alzheimer’s disease. → This protein-clearing effect was confirmed in vitro, ex vivo, and in vivo using mouse and nematode models. → βHB's effect on protein solubility is not dependent on covalent modification, pH, or solute load. → Ketone esters delivered to mice led to reduced brain protein aggregation. These findings suggest that ketosis may promote proteostasis (protein homeostasis), acting as a natural “janitor” for damaged proteins. This mechanism could be leveraged for therapeutic development in aging and neurodegenerative diseases (NDDs). ?? Key Takeaway Message: β-hydroxybutyrate helps clear misfolded proteins, highlighting its potential as a therapeutic target for aging and neurodegenerative diseases. — Madhavan et al., β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain, Cell Chemical Biology (2025) ?? Link to study: https://lnkd.in/gh3c8kaw ?? Find more research summaries on our website: https://lnkd.in/gKeXEcEN #Keto #KetoDiet #Research #Neurodegeneration #KetonesAndBrainHealth #AlzheimersResearch #MetabolicTherapy #AgingScience #Proteostasis

Does beef really increase cardiovascular risk? ?? A new systematic review and meta-analysis of 20 RCTs suggests minimal impact on key CVD risk factors, challenging long-standing concerns about red meat and heart health. Key findings: → No effect on total cholesterol, HDL, triglycerides, or blood pressure. → Slight LDL increase (+2.7 mg/dL), but this disappeared when one study was removed. → No significant impact on apolipoproteins or VLDL-cholesterol. These results suggest that daily unprocessed beef consumption does not significantly impact cardiovascular markers, indicating that other factors may contribute to observed associations in observational studies. ?? Key Takeaway Message: RCTs show unprocessed beef has minimal effects on CVD risk factors, challenging observational links between red meat and heart disease. — Sanders LM, Palacios OM, Wilcox ML, Maki KC. Beef Consumption and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Current Developments in Nutrition. 2024 Nov 2;8(12):104500 ?? Link to study: https://lnkd.in/gr92SZbM ?? Find more research summaries on our website: https://lnkd.in/gKeXEcEN #Ketogenic #CVD #Research #HeartHealth #BeefAndCardiovascularRisk #NutritionScience #HealthResearch #FoodAndWellness

Autism Spectrum Disorder (ASD) affects over 1 in 100 children globally and is associated with immune system changes, inflammation, and gastrointestinal issues. Abnormal gut flora is linked to ASD symptom severity. The ketogenic diet has shown promise in ASD improving symptoms by raising blood ketone levels, which may have neuroprotective effects. An interventional pilot study examined the effects of a modified ketogenic diet in seven children with ASD over four months. The diet was limited to 20-25 grams of net carbohydrate per day and included MCT oil supplementation. The study aimed to assess changes in microbiota, inflammation markers, and microRNAs. Key findings after 4 months on the ketogenic diet: - Decreased plasma levels of proinflammatory cytokines IL-12p70 and IL-1b - Increase in gut microbiota diversity - Increased expression of butyrate kinase in the gut - Reduced brain-derived neurotrophic factor (BDNF) levels (The authors suggest this might be due to more BDNF being used in the brain, reducing its amount in the blood) - Altered levels of brain-derived -associated microRNAs in plasma These results suggest that the KD may improve outcomes for those with autism spectrum disorder by reducing inflammation, correcting gut microbial imbalances, and affecting the BDNF pathway involved in brain activity. Larger studies are needed to look at how age and sex affect these changes, the duration of these changes, and how other gut chemicals like tryptophan and neurotransmitters impact brain activity and behavior. _______________________________________ Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K,Torres A, Peres R, Takahashi E, Maunakea AK. Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder. Nutrients. 2024 May 7;16(10):1401.doi: 10.3390/nu16101401. ?? Link to study: https://lnkd.in/gNRPFGU9 ?? Find more research summaries on our website: https://lnkd.in/gKeXEcEN #keto #ketogenicdiet #autism #research #ASDResearch #Neuroprotection

Weight loss & Body Composition: What Does the Science Say? ?? This week’s Spotlight on Keto Research focuses on the latest findings on dietary strategies for optimizing weight loss, lean mass preservation, and metabolic health. ?? Sustainable Weight Loss & Cost Savings – Therapeutic carbohydrate reduction matches GLP-1 therapies while reducing medication use. ?? Ketogenic & Low-Carb Diets in Weight Loss – What do clinical trials say about their impact on body composition and preservation of lean mass? ?? Insulin Response & Liver Health in Youth – How lifestyle choices influence MAFLD risk in overweight children and adolescents. ?? Time-Restricted Eating – The role of thermogenesis and inflammation in metabolic health. Metabolic research is evolving fast! Check out the latest studies below ?? #KetoScience #MetabolicHealth

Nutrition Network has a new Whole Body Health program. A 12-week, expert-led course focused on helping you take control of your metabolic health: ?? Weight loss & improved metabolism ?? Blood sugar stability & hormone balance ?? Sleep, movement & mindset ?? Expert guidance from dietitians, coaches, and physicians Whole Body Health launches on March 8, but you can sign up now and use the code ketomojo10 to receive a 10% discount: https://lnkd.in/dFNq6t8Y

Can a ketogenic diet improve mood stability and metabolic health in bipolar disorder? A new pilot study suggests promising benefits for both mental health and brain metabolism. Key findings from 6–8 weeks of a ketogenic diet in 20 individuals with bipolar disorder: → Higher ketone (BHB) levels were linked to: ?? Improved mood & energy ?? Lower impulsivity & anxiety → Metabolic improvements: ?? 9.2 lbs (4.2 kg) weight loss ?? 1.5 kg/m2 BMI reduction ?? 7.4 mmHg drop in systolic blood pressure → Brain metabolism shifts (MRS data): ?? Reduced glutamate & glutamine levels, which are often elevated in bipolar disorder These findings suggest that nutritional ketosis may offer therapeutic potential for mood stabilization, brain health, and metabolic improvements in bipolar disorder. However, larger trials are needed to confirm these effects. ?? Key Takeaway Message: A ketogenic diet may support mood stability, reduce anxiety, and improve metabolic health in bipolar disorder. — Daniel Smith Campbell IH, Needham N, Grossi H, Kamenska I, Luz S, Sheehan S, Thompson G, Thrippleton MJ, Gibbs MC, Leitao J, Moses T, Burgess K, Rigby BP, Simpson SA, McIntosh E, Brown R, Meadowcroft B, Creasy F,?Mitchell-Grigorjeva M, Norrie J, McLellan A, Fisher C, Zielinski T, Gaggioni G, Campbell H, Smith DJ. A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic, and magnetic resonance spectroscopy findings. BJPsych Open. 2025;11(2):e34. doi:10.1192/bjo.2024.841 ???Link to study:?https://lnkd.in/ePEfBky5 ?? Find more research summaries on our website:?https://lnkd.in/gKeXEcEN #Ketogenic #BipolarDisorder #BPD #Research #MentalHealth #KetogenicDiet #BrainHealth #MetabolicHealth #MedicalResearch

Post-Traumatic Stress Disorder (PTSD) is a complex mental health condition often accompanied by metabolic disfunction. Current treatments, such as psychotherapy and medications, have limited effectiveness for some patients. This feasibility study explored the potential of a 4-week ketogenic diet supplemented with exogenous ketones (KD-KS) as a dietary intervention for adults with PTSD. The study focused on ketosis maintenance, side effects, and acceptance. Three of four eligible patients were recruited, with two completing the full intervention. Key Findings: ??Achieving and Maintaining Ketosis: All participants reached ketosis (BHB ≥ 0.5 mmol/L) within the first two days, and ketosis was maintained for 87% of the intervention period. ??Adverse Reactions: No serious adverse reactions were reported, though mild to moderate side effects (e.g., headache, fatigue) were reported on 70% of intervention days. ??PTSD Symptoms: The PTSD Checklist (PCL-5) scores decreased by 20 points (from 70 to 50) and 10 points (from 50 to 40) in two patients over the 4-week period, indicating clinically significant improvements. ??Quality of Life (QoL): Improvement was observed across multiple QoL subscales, with six of eight subscales improving for one patient and three for another. This pilot study is the first to investigate a ketogenic intervention for people with PTSD, showing rapid attainment of ketosis, patient compliance, and potential improvements in PTSD symptoms and QoL. While these findings are promising, further studies with larger sample sizes must confirm feasibility, safety, and efficacy before larger clinical trials. — Maria Gabriela Persdotter Edwards Edwards MGP, Furuholmen-Jenssen T, S?egaard EGI, Thapa SB and Andersen JR (2024) Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study. Front. Nutr. 11:1406366. ???Link to study:?https://lnkd.in/gNaNSGJi ?? Find more research summaries on our website:?https://lnkd.in/gKeXEcEN #PTSD #ExogenousKetones #Supplementation #Keto #KetoDiet #Research

Can the ketogenic diet improve our dreams? This research focused on evaluating the effects of a very low-calorie ketogenic diet on sleep quality among women with overweight or obesity. Engaging 324 participants in a very low-calorie ketogenic diet for 31 days, the study assessed changes in both body metrics and sleep quality, utilizing the Pittsburgh Sleep Quality Index questionnaire for sleep evaluation. Results indicated that alongside notable improvements in anthropometric measures and body composition, the diet significantly boosted sleep quality. Correlations were observed between improved sleep quality and variables such as BMI, waist circumference, fat mass, and levels of high-sensitivity C-reactive protein (hs-CRP), with a reduction in fat mass being a primary indicator of enhanced sleep quality post-diet. The findings suggest that a very low-calorie ketogenic diet can beneficially affect obesity management and sleep quality in women with overweight or obesity, underscoring the role of sleep quality improvement in obesity treatment plans. Nevertheless, further studies are warranted to solidify these outcomes and explore the very low-calorie ketogenic diet's capacity to mitigate sleep issues in obese populations. — Barrea L, Verde L, Di Lorenzo C, Savastano S, Colao A, Muscogiuri G. Can the ketogenic diet improve our dreams? Effect of very low-calorie ketogenic diet (VLCKD) on sleep quality. J Transl Med. 2023 Jul 18;21(1):479. doi: 10.1186/s12967-023-04280-7. PMID: 37464397; PMCID: PMC10353204. ?? Link to study: https://lnkd.in/gigfKqxr ?? Find more research summaries on our website: https://lnkd.in/gKeXEcEN #sleep #sleepquality #keto #ketogenicdiet #nutritionaltherapy #research

From supporting cancer treatment to optimizing heart health, emerging research continues to highlight the power of metabolic interventions. Could dietary shifts enhance chemotherapy response? Lower blood pressure? Protect the liver? Improve exercise tolerance in heart failure? The latest science suggests so. This week’s Spotlight on Keto research dives into the fascinating connections between ketogenesis, gut microbiota, and cardiometabolic health. If you’re curious about how metabolic strategies are shaping the future of health and medicine, you won’t want to miss this. ?? Subscribe now to stay ahead of the latest research!