How Genomics Improves IVF and Fertility Treatment Outcomes? In this eye-opening conversation, biotech innovators share how genomics is reshaping IVF, offering a new hope for couples struggling with infertility. Guru Singh (Scispot), Jeremy Grushcow & Kaylene Ready (Juniper Genomics), dive deep into how genetic insights are not just improving IVF success rates but also reducing pregnancy loss. They discuss the challenges of transforming a deeply personal journey into a more successful and scientifically driven process. This is a must-watch for anyone interested in the future of fertility science and IVF.
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Juniper Genomics is shaping a better future for aspiring parents by enabling a faster, more successful IVF journey.
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https://www.junipergenomics.com
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I'm excited to participate in the 24th Precision Medicine World Conference (PMWC 2025) at the Santa Clara Convention Center, CA (Feb 5-7)! I will be presenting "The Future of Fertility (is Genomics)" and sharing information and data about Juniper Genomics' new PGT test! Come by the presentation or visit me and my colleague Adam Reeves at our booth to learn more about why euploid IVF transfers fail. #PMWC25 #WomensHealth #IVF #genechat
Co-founder & President, PMWC Intl / 33,000 LI Followers / PMWC Newsletters 92,000+ subscribers since 2009- SORRY, UNABLE TO ACCEPT MORE CONNECTIONS DUE TO THE LINKEDIN LIMIT
Trimester Zero: The Missing Piece in Maternal Health at PMWC 2025 ? What if the key to a healthy pregnancy starts in Trimester Zero? Viewing pre-pregnancy as critical to shaping outcomes is transforming maternal care. Recent research reveals that optimizing health before conception can reduce miscarriage risks, improve pregnancy outcomes, and positively affect lifelong wellness for both mother and child. Symptoms causing infertility in some women can also result in unhealthy pregnancies for others—even after conception. Addressing these early indicators during the pre-pregnancy phase can unlock new strategies for preventing pregnancy-related complications. At PMWC 2025, Feb 6th Women's Health Track: Yoel Sadovsky, University of Pittsburgh School of Medicine: Introduction to Data-driven Phenotyping of Pregnancy Health Diana W. Bianchi M.D., Eunice Kennedy Shriver?National Institute of Child Health and Human Development (NICHD): Prenatal Cell-Free DNA Sequencing and Incidental Detection of Maternal Cancer Paolo Rinaudo, UCSF Center for Reproductive Health: Harnessing Data to Enhance Fertility Research Vittorio Sebastiano, Biomarkers of Aging Consortium, Turn Biotechnologies: Stem Cells in Fertility and Aging Ruth Lathi, Stanford Fertility and Reproductive Health Center: Differentiating Miscarriages – Maternal vs. Fetal Aleksandar Rajkovic, UCSF Health: Genetic Insights into Uterine Fibroids and Fertility Priya Pantham, UCSD: Advances in RNA-Based Biomarker Discovery Leslie Manace, MD MPhil, Kaiser Permanente: Prediction of Pregnancy Health ?? Additional Showcase Presenters for Women’s Health: Kaylene Ready, Juniper Genomics: Genomic insights in IVF to make pregnancy clearer, faster, and more affordable. Andrew J Holman MD, Immedix: Utilizing immuno-diagnostic tools to assess immune dysfunction and improve maternal-fetal health through precision diagnostics. Christine Eng, Baylor Genetics: Specializing in diagnostic genomic sequencing, including its applications in prenatal and maternal health care. Dinah Weissmann, ALCEDIAG: Focusing on innovative diagnostic approaches for early detection of psychiatric disorders, which may intersect with maternal mental health. Eva R?smann, Lexogen: Specializing in RNA sequencing technologies to analyze gene expression changes during pregnancy and fertility treatments. ?? Explore how Trimester Zero could revolutionize how we approach women's health, and discover the potential to predict and prevent pregnancy syndromes through cutting-edge research. ?? February 5-7, 2025 ?? Santa Clara Convention Center REGISTER: https://lnkd.in/g9j9UnKS #PMWC25 #WomensHealth #MaternalCare #PrecisionMedicine PMWC - Precision Medicine World Conference, Mia Nease
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The metrics we use to measure outcomes matter. The IVF process puts a huge burden on women’s bodies and intended parents mental health, and 8,500 miscarriages are not collateral damage. Technological advances like PGT should be framed not only in terms of success rates or efficiency but also in their potential to honor the physical and emotional labor of those involved. Reducing miscarriages isn’t just a win for science—it’s a moral obligation to prioritize women’s well-being and to challenge the idea that enduring suffering is the cost of creating life. Thank you Tony Gordon, Santiago Munne, and Darren Griffin! ?? ?? ?? #IVF #fertility #womenshealth
Were 8500 miscarriages avoided with PGT-A? It's great to see the first snapshot analysis of the 2022 SART preliminary data by Santiago Munne and Darren Griffin. It's free to access at https://lnkd.in/gpis8zVm. There will be more analysis of this dataset no doubt but it did get me thinking, especially Figure 3 (see below). So doing my "back of the envelop analysis" of miscarriage rates with PGT-A (82K cycles intended retrieval) and (56K) without PGT-A. What would have happed to those 82K cycles if they hadn't had PGT-A? I haven't run the stats yet, but the numbers are huge for this dataset and the differences are clear. The difference in miscarriage rates are stark for the all age groups over 35yrs eg. 35-37yr - PGT-A 12.9 vs non-PGT-A 20.8 eg. 41-42yr - PGT-A 14.8 vs non-PGT-A 39.0 The 56K non-PGT-A cycles resulted in 17.6K miscarriage The 82K PGT-A cycles resulted in 10.5K miscarriage. So what if we hadn't performed PGT-A on those 82K cycles? Well we would have seen an additional 8.5K miscarriage (assuming the non-PGT-A miscarriage rate for each age group. The PGT-A group had a slightly lower proportion of patients over 38yrs than the non-PGT-A group hence why this isn't higher at the same overall % as the non-PGT-A group). Sometimes we look at the numbers from papers without considering the individual impact. No doubt we will still argue about the usefulness of PGT-A (no it doesn't improve cumulative LBR if you transfer every embryo in a cycle) but the effectiveness on the reduction the number of miscarriages is clear. On a individual level the impact is huge.
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Hey, it's #GeneticCounselorAwarenessDay! GCs are the most knowledgeable, dedicated, compassionate, thoughtful and hard working medical professionals on the planet. Thank you so very much to all of you who have made so many of our journeys so much better! In particular at Juniper Genomics we are grateful to Shivani Nazareth, our SAB chair, Kaylene Ready, our new Chief Product Officer, and everyone who's helped us think about how to best help #IVF patients on their #ttc journeys: Andrea Djolovic, CCGC (GenomiCare Genetic Counselling), Pamela Callum (Tandem Genetics), Andrew Faucett, Jenna Stoltzfus, Molly McGinniss, Carrie Haverty! Also thank you to the many others who have helped informally in the way GCs always do: with insightful questions and deep caring. Enough words - now action! If you are an organization who wants to support GCs, consider signing on to this letter: https://lnkd.in/d56VGAmi. Or just let your community know why genetic counseling matters by sharing your experience or following and sharing posts from the?National Society of Genetic Counselors!
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Come meet our team at Booth 147 at #asrm2024 and talk to us about why euploid transfers often don’t succeed, and what we’re doing about it! Jeremy Grushcow Kaylene Ready Dan Legault
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?? Happy?#WorldEmbryologistDay! ?? Your dedication and expertise turn dreams into reality for countless families. Thank you for all you do to make family-building dreams come true for so many! ?? Special thanks to?@alease_the_embryologist?for her help with this design and be on the lookout for awesome new Embryology merchandise coming soon!
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Come join the team the team for our recently announced GAPP Project , funded by Genome Canada and Génome Québec where you’ll be working directly with Sophie Petropoulos and collaborating with the team at Juniper Genomics on our mission to improve IVF outcomes. We're looking for a creative bioinformatician for a fully-funded industry partnership post-doc role who has broad experience with NGS and transcriptomics data. Applicants working in time zones across Canada, the US, and Europe are welcome! Diversity doesn’t come from checklists - if you are excited about making a difference in IVF and even a few of the details in the job match up, contact us anyway. https://lnkd.in/gP7cRcAr
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Congratulations to all the recipients! So proud to be working on our project to improve IVF outcomes with the brilliant Sophie Petropoulos and the whole team in her lab and at Juniper Genomics! Thanks also to the team at Génome Québec and to Alison Symington for all your guidance along the way! Learn more about our project here: https://lnkd.in/gAeXHraG
?? ?? Today, the #MinisterofInnovationScienceandIndustry, Fran?ois-Philippe Champagne, announced more than $17 million in federal support to eight new genomics research projects and four technology platforms funded through Genome Canada. Provincial governments, businesses and research partners are investing almost $24 million in co-funding, for a total investment of over $41 million. The eight projects announced today, part of Genome Canada’s Genomic Applications Partnership Program (#GAPP), will harness cutting-edge genomics science and innovative technologies and tools to deliver real-world impacts for Canadians and drive healthier, more sustainable and prosperous communities across Canada. Thank you, Innovation, Science and Economic Development Canada, for the thoughtful and important investment. #Sustainable #Funding #Future #PublicHealth More ? -> https://lnkd.in/gMFFcinA
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