IonOpticks

Big things are happening at IonOpticks. We’re excited to welcome Erik Verschuuren as our new Head of Global Sales, and Zac Anderson as Business Development Manager for North America. As our customer base continues to grow, their experience will enhance our sales and support functions and broaden our reach in key markets. With major product launches coming in 2025 - including advancements in proteomics, bioprocessing, and clinical applications - Erik and Zac will play a instrumental role in expanding collaborations and making our world-leading chromatography more accessible to researchers everywhere. Read the full announcement.

Congratulations to?Monash University's Proteomics & Metabolomics Platform for the latest milestone in their research capabilities, made possible through their relationship with Seer and Thermo Fisher Scientific. Their integration of Seer's Proteograph XT workflow with Thermo Fisher's Orbitrap Astral Mass Spectrometer and Aurora Series columns represents a significant leap forward in proteomics capabilities, with the ability to characterise more than 8,000 proteins across a human plasma study. We're proud to provide the essential connection that helps translate the Proteograph XT's sample preparation advantages into the extraordinary data acquisition capabilities of the Orbitrap Astral. It's great to be powering innovation in such a prominent facility and look forward to seeing the groundbreaking research that emerges from this platform. Learn more: https://lnkd.in/g6jHEVyZ

New insights into human brain development, a highly optimised workflow for proteomic analysis of FFPE tissue samples, and more. Learn about these and further recent developments in the world of proteomics in our latest newsletter. Read our February publication digest below and stay up to date.

As Day 2 of #USHUPO2025 gets underway, we’re loving the conversations and insights into the latest in proteomics research. It’s been especially interesting to hear how researchers are using IonOpticks products in new and novel workflows - a great chance for us to get feedback, understand the needs of modern labs, and shape future product lines. There’s still plenty of IonOpticks merch up for grabs, so swing by Booth 2 to grab yourself a set of hex keys, explore our latest application notes, connect with Erik and Zac and get a hands-on look at our latest products.

The poster sessions at #USHUPO2025 kick off today and there’s a lot of great research being done using our columns. Here are the posters we think are worth checking out on Tuesday: P01: Advances in Technology (P01.35) A novel nano HPLC system for high robustness and reproducible proteomics analysis. Dijana Vitko P02: Biomarkers and Targeted MS Assays (P02.19) Providing an analytical platform for state-of-the-art absolute apolipoprotein quantification in human blood plasma using prm-PASEF Dijana Vitko P07: Glycoproteomics and Glycomics (P07.11) State-of-the-art glycopeptide identification using an Orbitrap Astral mass spectrometer Julian Saba P08: High Throughput Proteomics – Tackling 1000+ Samples (P08.03) Considerations for Large Cohort Exploratory Studies: Proof-of-Concept Using Stage-IV Oncology Plasma from 500 Donors Danielle Gutierrez Check out our full list for the conference: https://bit.ly/4hjPGhf

A lively and informative presentation by IonOpticks’ own Dr Daniela-lee Smith, PhD at #USHUPO2025 on how to improve proteome coverage and reproducibility in large-scale analyses using packed emitter columns. An excellent showcase of the performance gains Aurora Series columns can provide with some incredible data supplied by Karl Mechtler and Johannes Bruno Müller-Reif utilising the Aurora Rapid 8x75 and Aurora Rapid 8x150 respectively. To learn more about these products and workflows, stop by booth 2 in the exhibition hall to continue discussing how good chromatography is crucial for optimising coverage while maintaining high reproducibility.

A great selection of poster presentations at #USHUPO2025 today from PreOmics, SCIEX, Bruker Daltonics and Thermo Fisher Scientific plus many more. A great showcase of sensitivity, depth and reproducibility - made possible by our famed Aurora Series chromatography.

Day 1 of #USHUPO2025 is off to a flying start. It’s great to be back in America, reconnecting with peers across academia and industry. While Philadelphia may be cold right now, the conversations at the welcome reception and opening sessions have been nothing but warm and engaging. Our team is here all week to talk all things chromatography - be sure to stop by the booth to meet our new sales leaders, Erik and Zac. And don’t miss Daniela-lee’s oral presentation at 2:20pm this afternoon in the main plenary hall.

An innovative method for resolving the molecular complexity of cellular structures has emerged: Filter-Aided eXpansion Proteomics (FAXP). Developed by Dong et al. at Westlake University, FAXP integrates hydrogel-based tissue expansion techniques with mass spectrometry to advance spatial proteomics research. Validation of the workflow was conducted across digested sections of nuclei, cells, and blank controls, analysed using an Orbitrap Astral interfaced with a Vanquish Neo, utilising an Aurora Elite XT for peptide separation. The results demonstrated a 14.5-fold increase in volumetric resolution, an 8-fold rise in peptide yield, and over 255% more protein identifications compared to previous methods. FAXP allows researchers to pinpoint regions of interest with precision while cutting sample preparation times in half. This makes high-resolution proteomics more accessible and paves the way for applications in cancer research, biomarker discovery, and precision medicine. Learn more: https://bit.ly/3ES1HwJ

One more day until Queensland Mass Spectrometry Symposium (QMSS) 2025 kicks off at the Griffith University Institute for Biomedicine and Glycomics. Aaron, our Senior Research and Development Scientist, will be attending on both days, February 20-21, to learn, network, and soak in the latest innovations and insights in mass spectrometry as a delegate. We may not be exhibiting, but Aaron loves chatting all things IonOpticks and how we can support your high-sensitivity LC-MS workflows. Are you attending? See if you can spot Aaron - he'd love to connect and have a chat. See you on the Gold Coast. #Proteomics #MassSpec #Chromatography