International Society of Glomerular Disease

The ISGD team is enormously grateful to everyone who attended the #ParasolProject public scientific workshop this week, as well as the project team led by PI Laura Mariani, the top-notch biostats group led by Abigail Smith who went above and beyond to analyze the *largest ever collection* of FSGS patient-level data, patient and clinician panelists, and especially our regulatory colleagues at FDA for their insights and participation. It has been our privilege to co-manage this project and it doesn’t end here. Stay tuned for a meeting summary this week and save the date for an additional presentation at ASN Kidney Week on the 25th!

Nephrologisches Seminar in Heidelberg - immer ein Highlight, speziell zu Beginn der nephrologischen Ausbildung!

Reminder: Join us on Tuesday, November 12, at 4:00 PM ET for the first webinar in an exciting new KDIGO webinar series on implementing genetic testing for CKD. Register: https://lnkd.in/emBM4aCr Professors Andrew Mallett, MD, Ali Gharavi, MD, and Hila Rasouly, MD, will discuss key messages from KDIGO guidelines on the prevalence of genetic causes of CKD and foundational principles in the role of genetics for CKD management. This webinar will also provide an overview of key logistics for genetic testing. We hope to see you there! #genetics #CKD #KDIGOwebinars

My Sunday News: ?? Registration for the 2025 ERCSG (European Renal Cell Study Group) Meeting is now open! ?? ?? www.ercsg2025.com We are excited to announce that the registration portal for the 2025 ERCSG meeting is now open and you can start submitting your abstracts! ?? ??This fantastic event brings together young researchers, postdocs and PIs to share and discuss the latest breakthroughs in kidney research, but also to network (researcher & companies). The most renowned clinicians and researchers in the field of glomerulopathies and glomerular basement membrane (GBM) will give keynote lectures, making this event a must-attend for everyone in the kidney field.?? Highlights of the meeting include: ? An extraordinary scientific program with outstanding keynote lectures. ? A warm welcome from the executive board & dean of Uniklinikum Greifswald. ? An expected welcome address by Health Minister Drese or her state secretary. ? A visit to the beautiful city of Greifswald and a tour to my institute of Anatomy and Cell Biology (visiting the anatomy museum and the zebrafish facility). ? A fantastic final event??. ??Researchers and clinicians from around the world are warmly invited to attend!?? ?? Don't miss out the opportunity to participate, since the number of participants is limited and apply for a travel grant! Register now and join us in making this event an unforgettable experience for the whole nephrology community! ????

Was Sie hier sehen, ist kein Kunstwerk oder eine Sternengalaxie – es sind kranke Nierenzellen. Um genau zu sein: Die Aufnahmen des konfokalen Laser-Scanning-Mikroskops zeigen blau eingef?rbte Zellkerne, sich darum windende rote Podozyten und das Nephrin-Protein, das feine grüne Lichtpunkte als Zeichen seiner Phosphorylierung zeigt. Ein Sinnbild für die intensive und erfolgreiche Erforschung eines lange ungekl?rten Nierenleidens durch Expert: innen des UKE, denn diese Nierenerkrankung ist die h?ufigste Ursache für substanziellen Eiwei?verlust im Kindesalter. Bisher wurde die Erkrankung ?Idiopathisches nephrotisches Syndrom“ genannt, es war lange unklar, welche Ursache hinter dem Syndrom steckt. Prof. Dr. Tobias Huber, Direktor der III. Medizinischen Klinik und Poliklinik des UKE und sein Team um Dr. Felicitas Hengel und Priv.-Doz. Dr. Nicola M. Tomas konnten dies nun herausfinden. Mit einer Studie konnten sie nachweisen, dass es sich in den weitaus meisten F?llen der betroffenen Kinder und zu einem erheblichen Teil auch bei den Erwachsenen um eine Autoimmunerkrankung handelt. Das Immunsystem bildet Antik?rper gegen die Filterstrukturen der Nierenzellen. Das entschlüsselte Leiden hei?t künftig ?Anti-Nephrin-Autoantik?rper-Erkrankung“. Nierenerkrankungen betreffen aktuell weltweit zehn Prozent der Menschen, doch sie werden h?ufig untersch?tzt. Sie sind meist schmerzlos und bleiben daher lange unentdeckt, oft mit schwerwiegenden Folgen. Die Erkenntnisse werden inzwischen in einer ersten Gentherapie in einem pr?klinischen Modell erfolgreich umgesetzt – ein Schritt in die richtige Richtung. Den ganzen Beitrag sowie viele weitere spannende Themen aus dem UKE finden Sie in der neuen Ausgabe unseres Forschungsmagazins wissen+forschen: https://t1p.de/ob10x Sie m?chten ein Exemplar nach Hause? Schrieben Sie einfach eine kurze Mail an [email protected]. #UKEHamburg #ForschungistdiebesteMedizin #Niere?

Exciting news for early-career nephrologists: The KDIGO Guideline Methodology Fellowship Program is now accepting applications! This inaugural KDIGO program is designed to educate and support early-career nephrologists and trainees while expanding the community of clinicians skilled in guideline development. The fellowship will provide an exceptional opportunity to learn directly from global leaders in nephrology and methodology and gain formal training and first-hand experience in KDIGO's world-renowned guideline development process. Applications are due by January 6, 2025. Learn more: https://lnkd.in/g85F_6pm

See you in Palm Springs at this Loma Linda University conference. Looking forward to seeing you all at this meeting, a great way to end a year of more progress in glomerular disease.

The KDIGO 2025 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD) is available for public review through Friday, November 22. You can download the public review draft and share comments via the feedback survey on the KDIGO Anemia in CKD Guideline Website: https://lnkd.in/eq87D-93 KDIGO will prepare a final version for publication based on feedback received during public review. We thank you in advance for your time and insights. #anemia #CKD

Join us for "Hiding in Plain Sight: The Utility of Genetic Testing in Common Forms of CKD," the next module?in KDIGO's new webinar series on implementing genetic testing for CKD. Wednesday, December?4, at 3:00 PM EST. Register:?https://lnkd.in/eUx9eWrn In this CME webinar, Professors Andrew Mallett, Emilie Cornec-Le Gall, Judy Savige, and Katalin Susztac will discuss the utility of genetic testing in common forms of CKD. The webinar will also examine the role of genetic testing in diagnosing cystic kidney disease, glomerular disease, and APOL1 kidney disease. ? Learn more:?https://lnkd.in/eBenU-f7

Sharing our research letter examining albuminuria quantification after an abnormal urine dipstick protein test in >1 million US patients. Q: How often is an abnormal protein on a urine dipstick test followed up with a quantitative test (e.g. albumin/creatinine ratio)? A: Only 6.7% of the time in 1 year. Lots of opportunities to improve detection kidney disease earlier and prevent future cardiorenal risk! https://lnkd.in/eJ_Nxjcw Also see nice medscape write-up and commentaries https://lnkd.in/ewWPHZjm