Institute of Technical Chemistry (TCI)

We look forward to welcoming our guests to the TCI's traditional summer colloquium and party!

New week, new publication! ?? Excited to share our latest work in Organic Process Research & Development: "Assessing the Industrial Edge of the Lipase-Mediated Oxidation of 2,5-Diformylfuran to 2,5-Furandicarboxylic Acid: Rotating Bed Reactors, an 'Acyl-Donor-Free' Oxidation Concept, and Environmental Aspects." Our study explores innovative, sustainable methods for FDCA production—a key building block for eco-friendly polymers. Congratulations to Milica Mili?, Guillem Vernet Armengol, Hai Yen Le, Ningning Zhang, Emil A. Bystr?m, Pablo Domínguez de María, and Selin Kara for this achievement! https://lnkd.in/eiCYtY9V

New publication! We’re excited to share our latest research, "Linkers in Action: Exploring Fusion Enzymes for Oxyfunctionalizations in Non-conventional Media through Experiments and Simulations," now published in ChemCatChem! ?? Congratulations to Yu Ma, Jan Philipp Bittner, Guillem Vernet Armengol, Ningning Zhang, and Selin Kara for this great work! This study explores how linker design impacts the performance of fusion enzymes for oxyfunctionalization in non-conventional media. Combining experiments and simulations, it provides valuable insights into enzyme engineering. ?? Read more: https://lnkd.in/ejy5ftRm

We're very happy to announce our latest publication in the research area of Process Analytical Technology (PAT) under the supervision of D?rte Solle. Phil Thiel and coworkers published their results with the title 'Development of a novel disposable flowcell for spectroscopic bioprocess monitoring'. The developed BioFlowCell enables the integration of spectroscopic measurements into modern disposable bioreactors and is universally applicable, representing a significant advancement in real-time monitoring of critical bioprocess?parameters. Congratulations to this excellent work! ?? https://lnkd.in/dZNa88pj

Congratulations to Jannik Richter! ?? Jannik defended his PhD thesis entitled 'Optimization and digitalization of a CHO cell culture process for recombinant mAb production' on Tuesday, 04. March 2025. His research was about the application of new machine learning tools and bioprocess modelling to improve productivity of CHO cells. We wish you all the best in Ulm! ?? Thank you also to the assessment committee! ??

Thanks to everyone who has been involved in the design of our DECADES video to share our scientific approach to the use of deep eutectic solvents in biocatalytic processes...Stay tuned for our results...more to come. https://lnkd.in/dsY_8RjT

Welcome to the official LinkedIn page of the Institute of Technical Chemistry (TCI) at Leibniz Universit?t Hannover! Led by Selin Kara, at TCI a broad range of?biotechnological research?is conducted. Currently, around 100 team members –group leaders, technicians, postdocs, doctoral candidates, BSc. and MSc. thesis students, and student helpers– are closely involved in our R&D activities and work on a wide variety of interdisciplinary and cross-sectoral research projects and cooperations between academia and industry. Our research projects are in the field of?industrial biotechnology, with a focus on biocatalysis, bioprocess technology, bioanalytics, cell culture technology, tissue engineering, bioreactor development, and respective computational applications. While a wide variety of our projects are purely fundamental research, the TCI regularly also has application-oriented collaborations with industrial partners reaching from start-ups to large enterprises. More to be found in: https://lnkd.in/de5qT2Dp