Global NASH Council

The Fifth Annual Liver Connect is being organized by Chronic Liver Disease Foundation (CLDF) in San Antonio, Texas (March 20-22,2025). This superb meeting covers cutting-edge information about most common liver diseases (MASH, viral hepatitis, ALD, cholestatic?liver disease, complications?of cirrhosis, HCC and pediatric liver disease) delivered by internationally renowned experts. The meeting will provide an opportunity to connect different stakeholders to advance the field of hepatology.?Zobair Younossi Chronic Liver Disease Foundation Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER European Liver Patients' Association - ELPA Saudi Society for the Study of Liver Disease and Transplantation Michael Betel Aleksander Krag Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong Robert Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Diane Langenbacher, PhD Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Victor de Lédinghen

The first APP guidance document for APPs is now fully published by members of the APP Committee?of the Global NASH/MASH Council. This article provides a very practical and easy to use approach about MASH that can be used in everyday clinical practice. Zobair Younossi Brian Lam Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER European Liver Patients' Association - ELPA Saudi Society for the Study of Liver Disease and Transplantation Michael Betel Aleksander Krag Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong Robert Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Diane Langenbacher, PhD Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Victor de Lédinghen

Save the date for the First Paris International Liver Meeting organized by highly recognized leaders in hepatology. Zobair Younossi Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER European Liver Patients' Association - ELPA Saudi Society for the Study of Liver Disease and Transplantation Michael Betel Aleksander Krag Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong Robert Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Diane Langenbacher, PhD Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Victor de Lédinghen

This year’s Annual DIMER DIABETES conference (November 21-23, 2024) was organized by Professor Mustafa Kanat (GNC Member) in Istanbul, Turkey. This superb international conference covered a large number of topics associated with diabetes, including MASH. The Global NASH/MASH Council was represented by Dr. Zobair Younossi who provided a comprehensive overview of MASLD including disease burden, risk stratification and treatment of MASH. He also encouraged global collaboration in MASH across subspecialties of hepatology/gastroenterology, endocrinology, cardiology, nephrology and other important areas. Zobair Younossi Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER Canadian Association for the Study of the Liver European Liver Patients' Association - ELPA Saudi Society for the Study of Liver Disease and Transplantation Michael Betel Aleksander Krag Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong Robert Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Diane Langenbacher, PhD Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Victor de Lédinghen

Sponsored by the Center for Outcomes Research in Liver Disease, the Global NASH/MASH Council (GNC) and the Global Liver Council (GLC) held their annual meeting on Sunday November 17th, 2024 at the AASLD 2024 conference. There were 93 members who attended (73 in person and 20 via virtual meeting) representing 29 different countries from across the globe. The leaders included those with expertise in hepatology, gastroenterology, endocrinology, primary care, pediatrics, nutrition, public health, public policy, patient advocacy and research. Several important issues related to MASLD, ALD, Met-ALD, Pediatric MASLD, Viral Hepatitis and Patient advocacy were discussed. In addition to participation in the GNC/GLC meeting, members presented multiple scientific papers during the meeting. Together these presentations help to meet the goals of the GNC/GLC which are to address and promote better understanding of the burden of different liver diseases across the globe. Through the inclusion of members from different regions of the world into our projects, we seek to gain a broader understanding of local, regional and global challenges and opportunities in different liver diseases across the world. Zobair Younossi Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER Canadian Association for the Study of the Liver European Liver Patients' Association - ELPA Saudi Society for the Study of Liver Disease and Transplantation Michael Betel Aleksander Krag Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong Robert Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Diane Langenbacher, PhD Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Victor de Lédinghen

It was a pleasure to participate in the Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference "Liver Cirrhosis: Common and Rare Complications". This highly successful scientific meeting was organized in Almaty, Kazakhstan (November 1st-2nd, 2024) by the Kazakh Association for the Study of the Liver (KASL) and Armenian Association for the Study of the Liver (ARASL) in collaboration with APASL. As a member of the Global NASH Council (GNC), Dr. Younossi presented a “State of the Art Lecture” about future global collaborations in areas of MASLD and other liver diseases with increased engagement from the region. We are grateful for the leadership of Professor Alexander V. Nersesov and Professor Hasmik L. Ghazinyan (both members of GNC) for organizing this outstanding scientific meeting and for their hospitality. GNC and its collaborative members from the region will be carrying out multiple projects to better understand the challenges and opportunities of different liver diseases in this important region of the world. Zobair Younossi Saudi Society for the Study of Liver Disease and Transplantation Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER Canadian Association for the Study of the Liver European Liver Patients' Association - ELPA Aleksander Krag Michael Betel Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Victor de Lédinghen Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Nikos Dedes Diane Langenbacher, PhD

It was a pleasure to participate in the Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference "Liver Cirrhosis: Common and Rare Complications". This highly successful scientific meeting was organized in Almaty, Kazakhstan (November 1st-2nd, 2024) by the Kazakh Association for the Study of the Liver (KASL) and Armenian Association for the Study of the Liver (ARASL) in collaboration with APASL. As a member of the Global NASH Council (GNC), Dr. Younossi presented a “State of the Art Lecture” about future global collaborations in areas of MASLD and other liver diseases with increased engagement from the region. We are grateful for the leadership of Professor Alexander V. Nersesov and Professor Hasmik L. Ghazinyan (both members of GNC) for organizing this outstanding scientific meeting and for their hospitality. GNC and its collaborative members from the region will be carrying out multiple projects to better understand the challenges and opportunities of different liver diseases in this important region of the world. Zobair Younossi Saudi Society for the Study of Liver Disease and Transplantation Fatty Liver Foundation EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER Canadian Association for the Study of the Liver European Liver Patients' Association - ELPA Aleksander Krag Michael Betel Faisal Abaalkhail Hirokazu Takahashi Onno (A.G.) Holleboom Jeffrey V. Lazarus Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Victor de Lédinghen Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa James Kim Prof. Shira Zelber Sagi Vincent Wong M Paula Macedo Didac Mauricio Philip Newsome NIKOLAOS PYRSOPOULOS Nikos Dedes Diane Langenbacher, PhD

The Global NASH Council (GNC) had a very successful meeting during the annual meeting of the Saudi Society for the Study of Liver Disease and Transplantation and Saudi Liver Meeting on October 19, 2024. Experts from Saudi Arabia, the golf region, and GNC presented up to date information about the burden and management of MASLD in the region. GNC and its collaborative members will be carrying out multiple projects to better understand the challenges and opportunities of MASLD and other liver diseases in this important region of the world. Zobair Younossi Saudi Society for the Study of Liver Disease and Transplantation Fatty Liver Foundation Chronic Liver Disease Foundation Hirokazu Takahashi Faisal Abaalkhail Onno (A.G.) Holleboom Michael Betel Jeffrey V. Lazarus Aleksander Krag Prof. Yusuf Yilmaz Mohamed El-Kassas Professor Manal Hamdy El-Sayed Massimo Colombo J?rn M. Schattenberg Scott Isaacs, MD, FACP, FACE Victor de Lédinghen Khalid Alswat, MD, FACP, MRCP, MBA-IHM khalid Al-Naamani Bandar Aljudaibi Naim Alkhouri, MD, FAASLD Mazen Noureddin, MD, MHSc Laurent Castera Mário Pessoa

It was an honor to lecture on NITs for MASLD at the Saudi Liver Meeting in Riyadh together with GNC chairman prof. Zobair Younossi and with prof. Hirokazu Takahashi on behalf of the Global NASH Council. It made me aware again that we have a joint assignment across the globe, working on the same matters: enhancement of timely detection of advanced MASLD fibrosis, raising awareness in the diabetes and obesity community and healthcare systems, and development of multidisciplinary care and pharmacological treatment for those who progress despite lifestyle interventions. Thank you prof. Faisal Abaalkhail, prof. Saleh Alqahtani and colleagues for the excellent scientific meeting and hospitality.

A very successful Inaugural meeting of NGM, SLMENA and GNC was held in Alexandria Egypt on October 10-11, 2024 to discuss hot topics in SLD by superb regional and international faculty. Zobair Younossi Fatty Liver Foundation Mohamed El-Kassas Prof. Yusuf Yilmaz Michael Betel Aleksander Krag Jeffrey V. Lazarus Chronic Liver Disease Foundation Professor Manal Hamdy El-Sayed Massimo Colombo