GI Oncology Now

?? Watch our new interview with Dr. Richard Kim of Moffitt Cancer Center, where he discusses a recent study that assessed the prognostic value and ability of #ctDNA to detect recurrence in patients with curatively resected early-stage biliary tract cancer: https://buff.ly/JzajSj4

? A retrospective cohort study has found that the addition of tumor deposit status to disease staging can improve prediction of prognosis in patients with #coloncancer: https://buff.ly/OpSEt16 ?? Sassun-Mayo N/TNM staging demonstrated superior OS stratification compared with current AJCC staging.

?? Data from a recent study has shown that the combination of #suvemcitug, #envafolimab and FOLFIRI chemotherapy for the second-line treatment of MSS/pMMR #colorectal cancer can boost OS and PFS:

?? A recent study has examined the genetic landscape of resistance alterations linked to KRAS targeting in KRASG12C-mutant CRC and #pancreatic ductal #adenocarcinoma. Resistance alterations correlated with a trend in worse overall survival in patients with KRASG12C #colorectal cancer in particular:

?? A new analysis of the IMbrave150 trial sought to determine the long-term survival outcomes and characteristics of patients with advanced HCC who achieve complete response from immunotherapy:

?? New data from the phase 3 COMPETE trial point to the efficacy of the radiotherapy agent 177Lu-edotreotide for the treatment of patients with grade 1 or 2 SSTR–positive GEP-NETs. ?? The primary objective of median PFS was significantly longer for patients treated with 177Lu-edotreotide than for those treated with everolimus:

?? New results from MATTERHORN have shown the efficacy of perioperative durvalumab with FLOT over perioperative chemotherapy alone for resectable early-stage gastric and GEJ cancers. ?? Learn more about the study led by Yelena Janjigian of Memorial Sloan Kettering Cancer Center: https://lnkd.in/eqvTxAvX

?? Catch up with some recent GI clinical trial updates with Dr. Sam Cytryn of Memorial Sloan Kettering Cancer Center as he reviews the latest positive results from MATTERHORN and DESTINY-Gastric04 for gastric and #gastroesophageal cancers: https://buff.ly/aadNjbD

?? A recent cohort study that evaluated the correlation between choledocholithiasis and #cholangiocarcinoma has found that the link between the two conditions is particularly high in older patients with extrahepatic CCA:

?? A lack of knowledge exists in understanding the influence of inflammatory markers on the prognosis of high-risk patients with #GIST. ?? To determine the link between certain factors and the prognosis of these patients, a recent multicenter analysis focused on RFS and OS as prognostic indicators: