FitBiomics

??? 5 hot takes on the Expo West + MISTA + Future Food Tech marathon (+ why I don’t care about RFK) 1) After all the GLP-1 friendly products at Expo, I was primed for the GLP-1 panel that opened the MISTA symposium. The panel featured dietitian Cate Ward, PhD, RD who shared stories of her patients with morning sickness-like symptoms and malnutrition on these drugs. GLP-1 drug side effects are an underdiscussed topic so I appreciated Cate's insights. I still expect growth to self-limit as people avoid the drugs over side effects. But there's no going back. We know now that regulating satiety, not enforcing willpower, is what works for weight loss. Food-as-medicine will pick up this opportunity, and the two growth curves will cross in 2026. 2) Can AI make better food? At FFT, Alexandre B. discussed how AI can stimulate creativity and eliminate trial and error. For cost reduction, manufacturing, etc, AI is a no-brainer. The jury is still out on AI for ideation of recipes and flavors. Are they tastier/healthier than our human intuition about food? The true test will be if an AI-informed product can outsell a control, as judged by real consumers. 3) Best moment at MISTA was Ian Roberts reminding us that, for many populations, “Better For You” isn’t about having better ingredients – it’s about having food, period. 4) Brands are going B2B, and B2Bs are launching brands. FoodTech startups are seeing corporates as their ideal customers in the long run. In the short run, launching a brand is still the fastest way to get revenue and product feedback. The challenge is these are two different businesses with different team DNA, but can be pulled off by talented founders. 5) What I didn’t see: Pet food. Expo West and Future Food-Tech are too quiet on this space. But pet food is where alternative proteins will find scale first, and is a fast growing segment for new brands. Pet food needs to be in the broader food system conversation. How do we get this done? Lastly, I heard so much worrying about RFK and policy uncertainty. But the fundamentals remain the same: climate change and pandemics are threatening the global food system; cocoa and egg prices are just a taste of what’s coming; global politics are increasingly unfriendly to trade. FoodTech is building the solution. The same technologies to futureproof our food system will bring healthier and more delicious products, and enhance longevity and healthspan. The next 4 years are a blip against these megatrends. In the meantime, US founders can commercialize freely in countries that are net importers of food and don’t have cultural baggage about “lab grown”. So keep calm and keep building ??????♂? PS. Thanks Steven Finn for capturing my first time eating cultivated meat at Mission Barns! And HUGE congrats to Natalie Rubio for winning the Supply Change Capital pitch competition! ?? Startups to watch: Akarso Bio FitBiomics Mothership Materials ZOLX Deco Labs New School Foods Maia Farms

Join the 10th Annual Microbiome Movement Summit - the premier global gathering for microbiome drug developers, uniting experts across discovery, preclinical, translational, regulatory, and commercial sectors to drive innovation in the microbiome space. Swipe to learn 5 reasons why June will be unmissable ?? ? Book your place now and maximize your savings with our early bird (ending midnight on Friday) - ???????? ???? ???? $?????? ????????: https://ter.li/m1pppt Want to know more? View the all-new brochure: https://ter.li/z3e6im Connect with companies such as: Ferring Pharmaceuticals Mikrobiomik Seres Therapeutics BiomeBank MaaT Pharma Azitra Inc Concerto Biosciences MRM Health AOBiome Therapeutics, Inc. Daré Bioscience, Inc. Microviable Therapeutics SL Seventure Partners Seerave Foundation Alveolus Bio FDA Unilever FitBiomics Nestlé Health Science Florey Biosciences Kanvas Biosciences Vedanta Biosciences, Inc. mbiomics GmbH List Biological Laboratories, Inc. #MicrobiomeMovement #MicrobiomeSummit #HealthcareInnovation #ResearchBreakthroughs #MicrobiomeScience?

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"The Nvidia of Wellness" Thank you Josipa Majic Predin and Forbes for sharing the FitBiomics story! ?? ?? ?? We had this crazy idea to translate the #microbiome data of the most fit people in the world into next-gen #probiotics to address critical #health needs in society. The craziest thing? IT'S WORKING. We're already redefining what's possible for Human health and #performance...and poised to do so for years to come. We're not a #supplements company....we're a Generational Health company. ?? ?? ?? #Nella #VNella #Exercise as #Medicine What's in your #Gut? https://lnkd.in/gnG_68xq

Excited to share that our Nella clinical manuscript was recently published in #Microbiome! Here w/ video: bit.ly/4hx8WrL What an amazing achievement for the FitBiomics team and the #probiotic industry. Nella began as an 'MVP' during the pandemic in March 2020 (we called it FITBIO at the time), and now our baby's all grown up as the ONLY probiotic clinically validated for #sleep #health benefits — while still delivering #gut health benefits to boot. Nella's journey is helping to redefine what probiotics can do for human #performance and #longevity. Here are a few highlights: 1. Accelerating microbiome discoveries. We used the "lean startup" method to flip the #translational #medicine paradigm on its head. Originally, we thought Nella would be a gut health product (it is), but through an open label study we empirically discovered the top benefit felt by consumers is sleep. Amazingly we validated this in a clinical follow-up, finding Nella improves sleep quality by 69%! 2. Gut-Immune-Brain axis. Nella reduces oxidative stress and inflammation biomarkers, which we propose as a potential driver of sleep benefits. 3. Nella improves microbiome composition and function, increasing B. longum and F. prausnitzii abundance, as well as increasing vitamin K biosynthesis. All while improving bowel movements by 37%. 4. Nella also boosts #energy by 31%, likely due to increased free testosterone-to-cortisol ratio and vitamin K production. All of this makes Nella truly unique as a 3-in-1 performance probiotic. And there's more... 5. The power of science: Our initial open label study was just 2-weeks, and still showed 94% of participants noticed health benefits. In a world where supplements are often seen as “nutritional insurance,” Nella delivers benefits users can rapidly FEEL. 6. Form fits Functions: Sleep is often called the "number one performance-enhancing drug." The Nella #Lactobacillus strains are isolated from the microbiomes of the world’s fittest people, who rely heavily on optimal sleep to perform. More fun stuff: We're expanding on wearable data showing Nella improves REM sleep and enables fewer sleep disruptions. We're also excited to further explore consumer feedback that Nella makes it easier to fall asleep as well as go back to sleep if they wake up in the middle of the night. Next steps? Exploring applications for #brain health, helping the 100M people with insomnia and sleep disorders, as well as applications for longevity and weight management (GLP-1 support). What's in your Gut? Tindaro Bongiovanni Marina Santiago Kinga Zielinska Carolina Barsa Dr. Ralf J?ger, MBA, FISSN Daniela Pinto Fabio Rinaldi Giammaria Giuliani Tullio Senatore Aleksandar D. Kostic Springer Nature ?? ?? ??