EUROoCS

??CALL FOR JOB POSTINGS?? Our EUROoCS community is thrilled to announce that we'll be regularly posting job openings in the dynamic field of Organ-on-Chip!????? ??If you are a member of EUROoCS and your lab has a job opening related to Organ-on-Chip research, we'd love to help spread the word! ? Reach out to us to showcase your opportunities to our network of researchers, scientists, and innovators. ? Let's collaborate and drive the future of Organ-on-Chip technology together! ? #OrganOnChip #ResearchOpportunities #EUROoCS

?? Meet the Members: Maria Tenje ?? Meet Maria Tenje, Professor in Microsystems Technology at Uppsala University. She leads the EMBLA research group at the Division of Biomedical Engineering at Uppsala University. Maria's research focuses on advancing organ-on-chip technologies and microfluidics for biological and life science applications. Curious to learn more? Check out the details below! ?? ?? We’re proud to feature such inspiring innovators in our community. #BiomedicalEngineering #MicrosystemsTechnology #Innovation #LifeSciences #EUROoCS #Organonchip #MeetTheMembers

?? Announcing the Third Edition of the Organ-on-Chip Summer School - a joint venture of the 3R-Center Tübingen and the EUROoCS’s #Teaching & #Training Working Group! ?? ?? Are you ready to dive into the future of #biomedical research? The #OrganOnChipSummerSchool2025 is back for its third edition! ?? Join us for an inspiring week of lectures, hands-on sessions, and networking opportunities focused on cutting-edge Organ-on-Chip (#OoC) and #MicrophysiologicalSystems (#MPS) technology! ??? Dates: September 15–19, 2025 ?? Location: Eberhard Karls Universit?t Tübingen, Germany ?? Why Attend? ??Expert Insights: Learn from leading academics and industry professionals on topics like #Microfabrication, #Imaging, #StemCells, #Biomaterials, #Microfluidics, #Sensors, #MicroelectrodeArrays (#MEAs), #InSilico modeling, and more! ?? Hands-On Training: Experience OoC technologies firsthand! ?? Networking: Connect with a vibrant community of #Researchers, #IndustryProfessionals, and fellow #Students ??! ?? Who Should Attend? ?? M.Sc., MD, #PhD students, and professionals passionate about advancing biomedical science ???????????? ?? Application Details: ?? Application Phase Starts: January 15, 2025 ??Limited Spots: Only 32 participants! Don’t miss this chance to explore innovative solutions for #DrugDevelopment, #DiseaseModeling, and human-centric #AlternativesToAnimalTesting! ?? ?? For more information, visit https://lnkd.in/eq_ErZ9e #SummerSchool #MPS #InVitro #3Rs #BiomedicalInnovation #EarlyCareerResearchers 3R-Netzwerk Baden-Württemberg NMI Naturwissenschaftliches und Medizinisches Institut

??CALL FOR JOB POSTINGS?? Our EUROoCS community is thrilled to announce that we'll be regularly posting job openings in the dynamic field of Organ-on-Chip!????? ??If you are a member of EUROoCS and your lab has a job opening related to Organ-on-Chip research, we'd love to help spread the word! ? Reach out to us to showcase your opportunities to our network of researchers, scientists, and innovators. ? Let's collaborate and drive the future of Organ-on-Chip technology together! ? #OrganOnChip #ResearchOpportunities #EUROoCS

??EUROoCS Digital Meeting: Anna Herland?? Neurovascular in vitro models - towards disease representation Don't miss out on our next EUROoCS digital meeting featuring Anna Herland as our distinguished speaker! ?? Mark your calendar for November 19th from 17:00 to 18:00 CET. Anna Herland is a Professor in Nanobiotechnology at SciLifeLab, KTH Royal Institute of Technology, and Karolinska Institute, Sweden. With a PhD in Organic Bioelectronics and postdoc fellowships in stem cell and tissue engineering, her research on organic electronics and microphysiological models of the central nervous system is groundbreaking. Join us to gain insights from over 70 peer-reviewed journal publications and 11 patents, as she explores the development of human primary and stem cell-derived systems with microfluidics and bioelectronics for real-time biological function assessment. ?? Date: November 19th, 2024 ? Time: 17:00 - 18:00 CET ?? Location: Virtual - Join from anywhere! ?? Register here: https://lnkd.in/erzFHMhF or use the QR code in the image. We look forward to your participation in this insightful session and the vibrant discussions it will spark! #EUROoCS #DigitalMeeting #Bioengineering #Nanobiotechnology #NeurovascularModels #InVitroModels #OrganOnChip #STEM #Innovation #Research #MPS #OoC

?? This week we have another exciting new research to share from one of our members, Mara Lucchetti, who conducted a study on a novel gut-liver platform which provides new strategies for drug development and personalized medicine. ?? The human microbiome significantly influences drug metabolism through the gut–liver axis, leading to modified drug responses and potential toxicity. Understanding the microbiome-driven impacts on drug metabolism is limited due to the complex nature of the human gut environment. To address this challenge, Mara and her co-workers from the Systems Ecology group at the Université du Luxembourg, along with Alexander Mosig's lab, have developed a multiorgan-on-a-chip (MOoC) system, mimicking the bidirectional interconnection between the gut and the liver known as the gut-liver axis. In a proof-of-concept study, the metabolism of irinotecan, a widely used colorectal cancer drug, was simulated within the MOoC. The researchers tracked irinotecan metabolites using liquid chromatography coupled to tandem mass spectrometry, confirming the platform's ability to represent drug metabolism along the gut–liver axis. Additionally, the study demonstrated that the colorectal cancer-associated gut bacterium, Escherichia coli, modifies irinotecan metabolism by transforming its inactive metabolite SN-38G into its toxic metabolite SN-38. This finding highlights the platform's robustness in investigating the intricate interplay between gut microbes and pharmaceuticals. "Our gut–liver platform, validated with irinotecan, lays the foundation for studying other drugs affected by gut microbes," the researchers noted. The MOoC platform serves as a powerful tool for exploring the complexities of drug metabolism influenced by the gut microbiome, offering a representative alternative to animal models. "Future applications of our platform hold promise for expanding our understanding of drug metabolism and microbiome interactions, contributing to advancements in personalized medicine and therapeutic interventions," the team added. ?? The research was published in Advanced Healthcare Materials and can be accessed at: https://lnkd.in/exHFVehE ?? The frontispiece of the study can also be viewed here: https://lnkd.in/e4PZxPyk This highlight was written by Anas Munir.

FIN OoC 2024 was a success! Warm thank you to all participants, sponsors, organisers and volunteers. ?? We had ?? 180 participants ?? 4 keynotes ?? 23 oral presentations ?? 32 posters ?? 20 universities and research organisations ?? 12 countries: Australia, Finland, France, Germany, Italy, the Netherlands, Norway, Portugal, Sweden, Türkiye, the USA, Vietnam Congratulations to the award winners ?? Best Poster: Fatma Zakzook, Tampere University ?? Best Oral: Erik Niemi, University of Jyv?skyl? ?? SAVE THE DATE! We are very excited to host FIN OoC 2025 8-9 Oct 2025! Warm thank you to our co-organiser: HaikaLab led by Heidi Haikala, University of Helsinki Tampere University Tampere University, Faculty of Medicine and Health Technology EUROoCS

?? We’re Back: Meet the Members of Tarek Gensheimer! ?? After a refreshing summer break, we're excited to return with the second post in our Meet the Members series! ?? This week, we're thrilled to introduce Tarek Gensheimer, a dedicated PhD student at the University of Twente, where he is working on Retina-on-Chip technology. ?? Check out the post below to learn more about his journey and contributions! #EUROoCS #MeetTheMembers #TarekGensheimer #Organonchip #PhD #Innovation

???2025 MPS World Summit: Call for Abstracts & Program Preview! We are very happy to be co-organizing the 2025 MPS World Summit (together with the iMPSS) in Brussels, Belgium, and we are thrilled to announce that abstract submissions are officially open! ?? This year’s program will focus on new developments in MPS and applications of MPS, which are divided into four key themes: ?? MPS Development and Results Processing ?? MPS for Biomedical Research and Disease Modelling ?? MPS for Efficacy, ADME, and Toxicity Testing ?? MPS for Industrial and Regulatory Testing ?? Submit your research and contribute to these exciting discussions—More details are below! ??? Abstract Submission Deadline: January 15, 2025, at 11:59 PM ET ?? https://lnkd.in/ghgDKMus ?? Explore the Preliminary Program: Dive into the future of MPS research with presentations and sessions designed to highlight the latest advances and applications in this evolving field. ?? https://lnkd.in/ga8D2uqy We hope you can join us in Brussels to share your work and connect with leaders on the latest scientific achievements in the MPS field. #MPSResearch #MPSWorldSummit #MPS #microphysiologicalsystems #organoid #organonchip #tissuechip #NAM #OoC #iMPSS

??2025 MPS World Summit: Call for Abstracts & Program Preview! We are thrilled to announce that?abstract submissions?for the?2025 MPS World Summit?(co-organized by EUROoCS)?Brussels, Belgium?are officially open! ???This year’s program will focus on new developments in MPS and applications of MPS, which are divided into?four key themes: ??MPS Development and Results Processing ??MPS for Biomedical Research and Disease Modelling ??MPS for Efficacy, ADME, and Toxicity Testing ??MPS for Industrial and Regulatory Testing ???Submit your research and contribute to these exciting discussions—More details are below! ????Abstract Submission Deadline: January 15, 2025, at 11:59 PM ET ???https://lnkd.in/ghgDKMus ???Explore the Preliminary Program: Dive into the future of MPS research with presentations and sessions designed to highlight the latest advances and applications in this evolving field. ???https://lnkd.in/ga8D2uqy We hope you can join us in Brussels to share your work and connect with leaders on the latest scientific achievements in the MPS field. #MPSResearch #MPSWorldSummit #MPS #microphysiologicalsystems #organoid #organonchip #tissuechip #NAM Lena Smirnova, Riccardo Barrile, James J. Hickman, Ph.D., Jan Lichtenberg, Magdalena Kasendra, Andries van der Meer, Mathieu Vinken