Entact Bio

?? Meet Micco Iwase! ?? As a co-op from Northeastern University, she is supporting our Molecular Discovery team by developing and running advanced assays to characterize the activity of ENTACs, the new class of drugs we're developing to enhance the function of beneficial proteins. With firsthand experience as a certified patient care technician, she knows just how vital advanced medications are to enhancing patients' quality of life. This passion has inspired her to explore the drug development side of healthcare. Fun fact, Micco is a proud plant parent of 7! ?? ?? Swipe through to learn more about Micco and her passion for addressing patients' unmet needs. #biotech #startup #CoOp

Hiring alert ?? Are you an experienced computational chemist or proteomics scientist? Join our efforts to expand the universe of treatable diseases. Check out these open roles! ?? Principal Scientist – Computational Chemistry and Modeling https://lnkd.in/exgfTzSx Principal Scientist – Proteomics and Chemical Biology https://lnkd.in/efuV9TvY #biotech #hiring #drugdevelopment #precisionmedicine #biotechjobs #computationalchemistry #proteomics #biologyjobs #sciencejobs #startupjobs #jobopening

??? October was Entact's annual?Health Month and we highlighted physical health, mental wellbeing, and team cohesion by coming together for outdoor team lunches, carving spectacular pumpkins, going for walks in glorious New England weather, and wearing pink in honor of #BreastCancerAwarenessMonth. We take pride in supporting each other in both work and wellbeing, and that spirit is part of what makes Entact a special place to grow your career! #biotech #startup

We're hiring! If you are an experienced proteomics scientist join our dynamic team as we pursue our mission of bringing novel therapeutics to the patients who need them the most. Check out the full job post to learn more ?? https://lnkd.in/efuV9TvY #biotech #hiring #drugdevelopment #precisionmedicine #biotechjobs #proteomics #biologyjobs #sciencejobs #startupjobs #jobopening #chemicalbiology #ubiquitin

Coming up next week: a nice opportunity to hear Entact CEO Victoria Richon share her expertise in building platform companies and discuss Entact’s unique approach to creating an entirely new class of drugs. Join us there: ??? Longwood Healthcare Leaders Boston CEO Conference ?? Expanding Platform Potentials Panel - October 28 - 11:10 - 11:40 am ET? ??Mandarin Oriental Hotel, Boston, MA Learn more about the event:? https://lnkd.in/eehfZ2xB #longwoodhealthcareleaders #biotech #drugdevelopment #precisionmedicine

From office to orchard, coming together as a team is at the core of who we are at Entact Bio! We recently took the opportunity to share a meal, enjoy the crisp fall air, and load up on delicious apples. Looking forward to another fantastic season of discovery as we work to expand the universe of treatable diseases at Entact. ???? #biotech #startup

We are pleased to officially welcome Ruben Tommasi to the Entact Bio team as our Chief Scientific Officer. A veteran drug developer with three decades of experience in the life sciences industry, Ruben has a proven track record in successfully advancing compounds from program inception to clinical development and regulatory approval. Ruben’s scientific leadership and experience in multiple therapeutic areas will progress our protein-enhancing ENTAC medicines to expand the universe of treatable diseases for patients in need. Learn more:? https://lnkd.in/eNSmdWaT

We’re delighted to feature Jian An, Principal Scientist on our Biological Sciences team, for our latest #EmployeeSpotlight! A biologist with over 10 years of drug discovery experience, Jian was drawn to the opportunity to work at a company that's pioneering a new therapeutic modality that enhances protein function–with the potential to benefit many different patients. As a program co-lead, Jian draws on his multidisciplinary training in cell biology and genetics and experience in drug development to drive the program forward. Jian’s colleagues recognize him not only for his drug discovery prowess but also for his infectious positivity, energy, and dedication, calling it a “recipe for success.” Also infectious is Jian's enthusiasm for a variety of pursuits beyond work, including hiking and calligraphy. An Entact highlight was a traditional tea ceremony that he co-hosted. Discover your role at Entact, working alongside Jian to build much-needed new medicines: https://lnkd.in/dSRqRK-K #drugdevelopment #precisionmedicine #biochemistry #drugdiscovery

With the new school year starting, we teamed up with our friends at Stellular Bio to fill backpacks for the local non-profit Catie's Closet, Inc, which provides school supplies and other necessities for students living in poverty in the Northeast. Back-to-school is a memorable time for so many of us, and we’re thrilled to play a small part in making sure kids have the tools they need to thrive in the classroom. Thanks to our teams for their generous donations. ??????

What are ENTAC? drugs? At their core, ENTACs — enhancement-targeting chimeras — are molecular matchmakers. These small-molecule drugs bring together beneficial target proteins with enzymes called deubiquitinases, or DUBs, which are key regulators of protein function. DUBs work by selectively shortening or removing chains of a molecule called ubiquitin that are attached to proteins. Whether the target protein: ? is in short supply ? is in the wrong place within the cell ? has suboptimal activity …an ENTAC can be designed to recruit a DUB to fix the problem. By introducing each target to the right DUB, ENTACs enhance the function of these crucial proteins — many of which cannot be targeted with existing drugs — ultimately restoring the cell’s health. Learn more about our science: entactbio.com/science