Echelon Biosciences

?? Sphingosine-1-phosphate?(S1P) is a lipid molecule that regulates many cellular processes, including cell growth, movement, and immune system reactions.?It's also involved in embryogenesis, angiogenesis, and cardiogenesis. S1P plays a significant role in inflammation and cancer. Two recent studies using the?Sphingosine 1-phosphate (S1P) ELISA (K-1900) https://lnkd.in/g8i6RjPm?from Echelon Biosciences determined that S1P is a possible biomarker for dangerous inflammatory lung disorders. Echelon’s S1P ELISA is a sensitive and robust method for quantification of S1P in biological samples. Learn More: https://lnkd.in/gNmFkh7c #Biotechnology #Lipids #ARDS #Cancer

?? Are you engaged in #porphyria research? We've got newly available compounds! Made in our Logan, Utah lab, our quality is guaranteed and backed by the decades of expertise from our #porphyrin chemists. ?? Available globally in 1mg, 5mg, and bulk: - #Uroporphyrin I (URO1) - #Uroporphyrin III (URO3) - #Heptacarboxylporphyrin I (HEPTA1) - #Hexacarboxylporphyrin I (HEXA1) - #Pentacarboxylporphyrin I (PENTA1) https://lnkd.in/g3jagdUm ---- #porphyriadisease #porphyriaresearch #organicchemistry #chemicalmanufacturer #americanmade #porphyrinresearch #smallbusiness

I am excited to share our recent "Current Issues" article in the American Journal of Preventive Medicine. We discuss the high potential of phosphatidylethanol (PEth) testing in routine medical care to improve detection and treatment of unhealthy alcohol use. We need to do more to detect and treat alcohol use that might be causing physical or social harm! https://lnkd.in/gaZWg8rZ

New Research Highlight is out! ?? https://lnkd.in/gVbzEayB Recent work by Ko et al. explores the critical role of PI(4,5)P2 (https://lnkd.in/gXRp4Rhf) in the activation of proton-activated chloride (PAC) channels. PAC channels open in response to extracellular acid, allowing anions to pass through cellular membranes. Extracellular acidity, acidosis, is a common pathological feature of ischemia and cancer and is known to activate a class of chloride channels that can trigger cell death. Ko and colleagues found that PI(4,5)P2 on the inner leaflet of the plasma membrane is necessary for the activation of PAC channels. Their findings provide new mechanistic insights to PAC activation and suggest a route for modulation of acidosis. Read the full article here: https://lnkd.in/gxaVmJJY Echelon has been Accelerating your Discovery since 1997, and is proud to have provided lipids for this research. Congratulations to Ko et al. on this important work! #Phosphoinositides #Lipids #Biotechnology

Echelon Biosciences continues to lead the way in?biochemical reagents,?assays, and?peptides?customized for?academic research?and?pharmaceutical development. With a strong focus on advancing the science of?lipid signaling, Echelon’s innovative research tools are designed to pave the way for drug treatments and diagnostics for debilitating diseases. As the?sole distributor?of Echelon Biosciences in India, BTL Biotechno Labs Pvt Ltd is excited to introduce their?newly launched Glycolipids for LNPs! ?6,6′-Trehalose Dioleate Glycolipids?can play a role in decreasing LNP toxicity. It can form hydrogen bonds with polar biomolecules, allowing the formation of a stable LNP structure by partially replacing the ionizable lipid. It can facilitate the development of mRNA vaccines with improved clinical safety. ?6-Trehalose Monooleate?can be used as antiaggregation agent for stabilization of proteins. It can also be used as a delivery vehicle for topical drugs by forming solid lipid nanoparticles. For more product specifications, please connect with us at [email protected]. Echelon Biosciences Cameron Day, Ph.D Paul Neilsen Colin Ferguson #LipidSignaling #Glycolipids #LNP #mRNAVaccine #PharmaResearch #DrugDevelopment #Biotech #EchelonBioscience #BTLBiotechnoLabsPvtLtd

Trouble delivering lipids into cells? ?? Fear not. Echelon has pioneered a simple, efficient & reliable method for delivering phosphatidylinositol phosphate (PIP) lipids into a wide range of cell types with our Shuttle PIP tools. One more way Echelon is helping to accelerate your discovery! See our full line of Shuttle PIP products: https://lnkd.in/gZ-hJ3MJ #Lipids #PIPs #Biotechnology

Trouble delivering lipids into cells? We hear you. ?? Echelon Biosciences has pioneered a novel approach for delivering phosphatidylinositol phosphate (PIP) lipids with our Shuttle PIP products. These tools are a simple, efficient & reliable method for delivering PIPs into a wide range of cell types. One more way Echelon is helping to accelerate your discovery! See our full line of Shuttle PIP products: https://lnkd.in/gZ-hJ3MJ Learn more: https://lnkd.in/gBq7U6-v #Lipids #PIPs #CellDelivery

Happy Mole Day! Celebrated on October 23 from 6:02 a.m. to 6:02 p.m., Mole Day commemorates Avogadro's Number (6.02 x 1023), a basic measuring unit in chemistry. One mole is a mass (in grams) whose number is equal to the molar mass of the molecule. Water has a molar mass of 18, so one mole of water weighs 18 grams. Generally, one mole of any substance contains Avogadro's Number of molecules or atoms of that substance. The theme for this year's Mole Day is "EncantMole". The Spanish word encanto has multiple meanings, including?"charm", "enchantment", "spell", "I love", or "I adore". Let's take this opportunity to celebrate the wonders of chemistry! #MoleDay #Biotech #Chemistry

Welcome to the PSL Alliance VION Biosciences! VION Biosciences is seeking to establish B2B connections within the #PSLAlliance for bioreagent products, including antibodies, antigens, and IVD assays. If you're interested in learning more about VION Biosciences or you have a business interest, please reach out to us: [email protected] or speak to Jemma Mason #PSLAlliance #Community #LifeScience #BusinessGrowth #Networking

We hope that you are enjoying our enhanced look and website! Features you would like to see? Drop us a line to let us know what you think! https://lnkd.in/efkU3BZ9 As you might have heard, Echelon was recently acquired by VION Biosciences. Echelon is now part of the VION family of companies including Ansh Labs and Aldon. We look forward to a bright future together! Echelon continues to provide quality products & responsive customer service to meet your changing scientific needs.?As ever, Echelon is your trusted partner in discovery. See Echelon's Fall newsletter for the full news roundup ?? https://lnkd.in/eb6B7YPG #Biotechnology #DrugDiscovery #News