DoseMe

?? Exciting News! ?? DoseMe is proud to announce our strategic partnership with DaiKnow to advance Model-Informed Precision Dosing (MIPD) in India! As precision dosing gains momentum in clinical practice, particularly with ???????????????????? ?????? ????????????????????, this collaboration ensures clinicians have access to the tools, technology, and education needed to optimize patient outcomes. ?? ?????? ???????? ??????????????: ?? MIPD is transforming how clinicians personalize dosing for better efficacy and safety. ?? Vancomycin AUC monitoring is becoming a key focus in infection management. ?? Through this partnership, DoseMe and DaiKnow are bridging the gap between scientific advancements and real-world clinical implementation. ?? “Precision dosing has the potential to significantly improve patient care and enhance global health outcomes,” says Vinay Singh, Managing Director at DaiKnow. Together, we’re driving the future of precision medicine—one dose at a time. Read the full release here: https://lnkd.in/ei3StCSK #PrecisionDosing #MIPD #HealthcareInnovation #Vancomycin #DoseMe #DaiKnow #India #PatientSafety #Pharmacokinetics #therapeuticdrugmonitoring #bayesianddosing #modelinformed #pharmacy #futureofmedicine #antimicrobialstewardship

?? Editor’s Choice Paper Alert! ?? Excited to share our latest study, published in Infectious Diseases Society of America Open Forum Infectious Diseases (OFID): ?? "Big Data Bayesian Truths: No Vancomycin Trough Concentration Target is Sufficiently Precise for Safety or Efficacy" ???? Authors: Justin S., Sharmeen Roy, PharmD, BCPS, Paul Sabourenkov, Marc Scheetz ?? A large-scale, international study (17,711 patients across the U.S., EU, and Australia) reveals major inconsistencies between vancomycin trough concentrations (Cmin) and true AUC targets. These findings reinforce the need for AUC-guided therapeutic drug monitoring (TDM). ?? Key Findings: ? Only 23% of paired trough and AUC values were within the target range. ? Categorical disagreement between Cmin and AUC was 34.3%. ? 30% of low trough levels (Cmin) still had target AUCs (400–600 mg × 24h/L)—leading to unnecessary dose escalations and increased nephrotoxicity risk. ? No clinically used trough range consistently predicted AUC targets with precision. ?? Why This Matters: ?? Supports 2020 IDSA/PIDS/SIDP vancomycin guidelines recommending AUC-based monitoring over traditional trough-based methods. ?? Bayesian-guided dosing enables model-informed precision dosing (MIPD) for safer, more effective therapy. ?? Prevents unnecessary dose increases, reducing nephrotoxicity risk. ?? Ensures optimal vancomycin exposure, improving treatment efficacy. ?? Reduces variability in dosing decisions, enhancing patient safety. ? Bottom Line: Trough-based vancomycin monitoring is too imprecise for safe and effective dosing. Bayesian AUC-guided dosing is the future of precision TDM. ?? Read the full study here: https://lnkd.in/evWHGdbw #PrecisionDosing #AUCNotTrough #Vancomycin #AntimicrobialStewardship #TDM #BayesianDosing #BigData #PatientSafety #DoseMeRx #ModelInformed #PrecisionMedicine

Big News for ?????????????????? ???????????????? ????????????????!? ?? Following our announcement with University Medical Centre Ljubljana and University Hospital of Maribor, ambulatory clinical pharmacy services in hospitals are now reimbursed in ALL Slovenian hospitals! This is a significant milestone that ?????????????????????? ?????? ???????? ???? ?????????????????????? and ensures ???????????? ?????????????? ???????? across Slovenia. Even more exciting—this sets a model for other EU countries, as ???????????????? is leading the way as a ?????????? ?????????? ???? ???????? ??????????! This achievement wouldn’t have been possible without the dedication of our partners, pharmacists, and supporters—especially University Hospital of Maribor, Ministrstvo za zdravje / Ministry of Health, and Zavod za zdravstveno zavarovanje Slovenije (Slovenian Insurance Company). A special thanks to the pharmacists and founding members of the Association who initiated, discussed, and championed this proposal. Your dedication has paved the way for ???????????????? ?????????????????????????? and expanded clinical pharmacy services in Slovenia. ?? Special recognition to: DoseMe supporters Maja Petre and Tomi Lapto?, along with Alenka Kova?i?, Samo Rozman, Tina Morgan, Monika Sonc, Sabina Gobec, Mojca Bla?i?, Sara Kenda, Marcela Omahen, Matej ?tuhec, PharmD, PhD, and the Slovensko farmacevtsko dru?tvo and Lekarni?ka zbornica Slovenije for their incredible contributions! ?? Learn more about Slovenia pioneering precision dosing with DoseMeRx in its national healthcare strategy: ?? https://lnkd.in/e2cxh28R It’s a great day for Slovenian patients and clinical pharmacy! ?? #ClinicalPharmacy #Slovenia #PharmacyInnovation #HealthcareSuccess #Pharmacists #PatientCare #therapeuticdrugmonitoring #bayesianddosing #precisiondosing #modelinformed #pharmacy #futureofmedicine #antimicrobialstewardship

Guess who’s featured on the latest ???????????????? ???? ???????????????? Podcast?! ??? Sharmeen Roy, PharmD, BCPS, Chief Strategy & Science Officer at DoseMeRx, discusses how precision dosing technology is revolutionizing pharmacy operations and improving patient outcomes with Mike Koelzer. ?? Don’t miss it! Tune in now to learn how ?????????????????????? can leverage technology for ??????????, ?????????????? ???????????? ?????????????????? and how validated, ??????-???????????????????? ???????????????? is enhancing clinical efficiency, minimizing medication errors, and ???????????????? ?????????? ???????????????????????? ????????????. ?? https://lnkd.in/efvsKmFw #Pharmacy #PrecisionDosing #ClinicalDecisionSupport?#therapeuticdrugmonitoring #bayesianddosing #precisiondosing #modelinformed #futureofmedicine #antimicrobialstewardship

?? Exciting news! ?? Join Mike Koelzer on Monday, 3/3, as he interviews our very own Sharmeen Roy, PharmD, BCPS, on The Business of Pharmacy Podcast? to discuss how DoseMe is transforming precision dosing. ?? Don't miss this insightful conversation on making better dosing decisions with fewer errors. Subscribe now: www.bizofpharmpod.com #Pharmacy #PrecisionDosing #Pharmacists #PatientSafety #DoseMe

?? iscientia Expands Portfolio with DoseMeRx to Revolutionize Precision Dosing in Healthcare The partnership brings DoseMeRx to hospitals across ??????????????, ????????????, ???????????????? ????????????-???????????????? ????????????, ?????? ??????????????????????, ?????? ????????????????????. This collaboration strengthens Iscientia’s comprehensive suite of healthcare solutions, empowering clinicians with personalized, data-driven medication guidance. ?? Why It Matters: ? Better Patient Outcomes – Precision dosing ?????????????? ???????????????????? to each patient, improving therapeutic success ?????????? ???????????????????? ?????????????? ??????????????. ? Combatting Antimicrobial Resistance – Optimized dosing supports stewardship efforts in the fight against drug resistance. ? Smarter, Safer Care – Clinicians gain real-time insights, ensuring every dose is the right dose. "As healthcare evolves, precision dosing is a critical shift in medicine," says Paul Edwards, CEO of DoseMe. "By integrating DoseMeRx, Iscientia is equipping healthcare providers with cutting-edge tools to enhance patient care and safety." ?? Iscientia’s Healthcare Innovation Ecosystem: ?? ???????????????? ???????? ?????????????????? – Evidence-based decision-making with seamless database integration. ?? ???????????????????? ???????????????????????? – Proprietary tools for smarter healthcare management. ?? ?????????????????? ?????????????? – Strategic regional partnerships to address unique healthcare challenges. Together, Iscientia and DoseMe are shaping the future of model informed precision dosing. Learn more about this groundbreaking partnership: ?? https://lnkd.in/eBDwBhEU #HealthcareInnovation #DoseMeRx #Iscientia #PatientSafety #PersonalizedMedicine #therapeuticdrugmonitoring #bayesianddosing #precisiondosing #modelinformed #pharmacy #futureofmedicine #antimicrobialstewardship

It is no coincidence we announced this exciting award for Sharmeen Roy, PharmD, BCPS on @International Day of Women and Girls in Science is celebrated on?February 11th.?We continue to recognize the contributions of women and girls in science and technology, and to encourage more women to pursue careers in STEM fields. Congratulations to all 50 women recognized by The Healthcare Technology Report! See full release here: https://lnkd.in/gb6DWK6d

A huge thanks to our coauthors on this (tagged below). The alternate title could have been, "Troughs are not enough to provide safe care to patients receiving vancomycin." Data from this paper dispel the commonly held belief that troughs are precise enough estimates of AUC. Since AUC is clearly linked to kidney injury, making sure you do not go over your target AUC is critical to patient safety.

????????????’?? ???????????? ??????????:?Excited to share the latest study, published in Infectious Diseases Society of America Open Forum Infectious Diseases (OFID): "?????? ???????? ???????????????? ????????????: ???? ???????????????????? ???????????? ?????????????????????????? ???????????? ???? ???????????????????????? ?????????????? ?????? ???????????? ???? ????????????????" ??????????????: Justin S., Sharmeen Roy, PharmD, BCPS, Paul Sabourenkov, Marc Scheetz ? A large-scale, international study (17,711 patients across the U.S., EU, and Australia) reveals significant inconsistencies between vancomycin trough concentrations (Cmin) and true AUC targets, reinforcing the need for AUC-guided therapeutic drug monitoring (TDM). ?????? ????????????????: ? Only 23% of paired trough and AUC values were within the target range. ? Categorical disagreement between Cmin and AUC was 34.3%? ? Most disagreement (7,959 Cmin levels, 30%) occurring with “low” Cmin but target AUCs (400–600 mg × 24h/L), leading to unnecessary dose escalations and increased nephrotoxicity risk. ? No clinically used trough range consistently predicted AUC targets with precision. ?????? ???????? ??????????????: ? Supports the 2020 IDSA/PIDS/SIDP vancomycin guidelines recommending AUC-based monitoring over traditional trough-based methods. ? Bayesian-guided dosing enables model-informed precision dosing (MIPD) for safer, more effective therapy. Clinical Impact: ? Prevents unnecessary dose increases that elevate nephrotoxicity risk. ? Ensures optimal vancomycin exposure, improving treatment efficacy. ? Reduces variability in dosing decisions, enhancing patient safety. ?????? ???????????? ????????: Trough-based vancomycin monitoring is too imprecise for safe and effective dosing. Bayesian AUC-guided dosing is the future of precision TDM. ?? Read the full study: https://lnkd.in/evWHGdbw #PrecisionDosing #AUCNotTrough #Vancomycin #AntimicrobialStewardship #TDM #BayesianDosing #BigData #PatientSafety #DoseMeRx #Modelinformed #precisionmedicine #

?? We’re thrilled to share that Sharmeen Roy, PharmD, BCPS Roy, Chief Science and Strategy Officer at DoseMe, has been recognized as one of the “?????? 50 ?????????? ?????????????? ???? ???????????????????? ???????????????????? ???? 2024” by The Healthcare Technology Report! ?? This prestigious award celebrates visionary leaders driving innovation, business growth, and meaningful advancements in healthcare technology. Sharmeen’s leadership has been instrumental in advancing ?????????????????? ???????????? and supporting hospitals in their shift toward ???????????????? ???????????????? ?????????????? ??????????—integrating Bayesian modeling and real-time monitoring to ?????????????? ?????????????? ????????. ?? “This achievement is a testament to the hard work and dedication of our entire team at DoseMe. We are committed to empowering hospitals with tools that enhance dosing accuracy, accelerate treatment decisions, and ultimately improve patient outcomes,” said Sharmeen Roy. ?? Congratulations, Sharmeen, on this well-deserved recognition! Your leadership continues to shape the future of healthcare technology. ?? Read more about the award and the full list of honorees here: https://lnkd.in/gb6DWK6d #Leadership #WomenInTech #HealthcareInnovation #PrecisionDosing #AIinHealthcare #DoseMeRx #PharmacyTech #modelinformed #Bayesian