Come visit our poster #764 today (11/09) at #SITC2024! We’ll showcase the advantages of DNA Origami nanotechnology and its applications in #CancerImmunotherapy. Discover the latest updates on our cancer therapeutic vaccine, including a comparison with #mRNA vaccines conducted by the team @Shih lab at Harvard University, Wyss Institute, and Dana-Farber Cancer Institute. Our work has been published in Nature Nanotechnology, Small Methods, and several preprints on bioRxiv. We’re excited to translate the cutting-edge advances at DoriNano into real solutions for patients. Looking forward to connecting with you at SITC! #CancerResearch #Immunotherapy #Biotechnology #Nanotechnology #Innovation #LifeSciences
关于我们
DoriNano leverages DNA origami nanoparticle as a groundbreaking delivery platform to develop combination immunotherapies with sophisticated nanoscale precision.
- 所属行业
- 生物技术研究
- 规模
- 2-10 人
- 类型
- 个体经营
- 创立
- 2024
DoriNano员工
动态
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DoriNano is pleased to announce that?Raymond Stapleton, Jr., Ph.D. has joined the team as a strategic advisor to help guide the process development, scale-up and manufacturing of DoriVac-101, our DNA origami nanoparticle vaccine. We are honored to be able to build from?Ray's extensive experience establishing manufacturing capabilities and bringing novel drug product candidates to and through clinical testing.?Welcome,?Ray! Check more here: https://lnkd.in/edJ-eZuD
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Proud to share our latest video created by the Wyss Institute, come to meet our female management team and groundbreaking work in DNA origami technology. A huge thanks to our dedicated team and collaborators for making this progress possible!
Excited to share this video made by the amazing team Wyss Institute at Harvard University showcasing our work DoriNano. We're pushing the boundaries with DNA origami technology to tackle some of the toughest challenges in nanodelivery industry. At DoriNano, we're committed to advancing innovative therapies for serious diseases, and this video highlights the groundbreaking potential of DNA origami delivery systems and the progress we're making thanks to a great team and partners Jessica Baker Flechtner and William Shih. Huge thanks to everyone who has been part of this! #Biotech #Innovation #CancerResearch #DNANanotechnology #WyssInstitute #DoriNano https://lnkd.in/eXiHcJC2
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A journey of a thousand miles may not be achieved without accumulation of each single step, just as the enormous ocean may not be formed without gathering every brook or stream. https://lnkd.in/eHj6NbTk
?? I'm thrilled to share that our team at Dana-Farber Cancer Institute and Wyss Institute at Harvard University has just published two more preprints on bioRxiv! As the corresponding author, alongside Dr. William Shih, I'm incredibly proud of the work we've done to advance the DNA origami research field. In these studies, we delve into the economic fabrication of DNA origami and the methods for quantifying the cargo they carry. This represents a significant step forward in our mission to advance DNA origami technology towards therapeutic translation. A huge thank you to my amazing co-authors and collaborators for their dedication and hard work: Olivia Arnold, PhD (Young), Hawa Dembele, Anjali Rajwar, Giorgia Isinelli, and Chris Wintersinger. Your contributions have been invaluable! ?? Check out the full preprints here: https://lnkd.in/ep45n_3A https://lnkd.in/e9kM9GAn #biotech #research #DNAorigami #innovation #science #DoriNano #bioRxiv #preprint #therapeutics
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We are excited to welcome Jessica Baker Flechtner as the Co-founder and CSO/COO of DoriNano! Jessica brings a wealth of experience and expertise in immunology and cancer vaccine development, previously serving as the CSO of Genocea. Her leadership and vision will be instrumental as we advance our groundbreaking work in DNA origami technology. We look forward to her contributions in driving innovation and achieving our mission to revolutionize the biotech field. Join us in welcoming Jessica to the DoriNano team! Together, we are poised to make significant strides in biotechnology.
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We are thrilled to announce that DoriNano now has an official online presence! Visit our brand new website at DoriNano.com to learn more about our groundbreaking work in DNA origami technology and how we're pioneering innovative solutions in the biotech field. Explore our research, meet our team, and discover partnership opportunities. This is just the beginning of our journey to revolutionize the world of biotechnology. Thank you to everyone who has supported us so far. We look forward to your continued support and collaboration.
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Thank you, MassBio. DoriNano is honored to have graduated from the #MassBioDrive program. https://lnkd.in/eQUmjHZv
Thank you to our #MassBioDrive Spring 2024 cohort mentors! Gadi G. Bornstein, Ph.D. | Michael Boss | Atul Deshpande Ph.D., MBA, A-PMP | Jean Ge, PhD | Alex Goddard, Ph.D. | David Hayes | Arthur Hiller | Alexis Hofherr | Dominic McDonald | Shreya M. | Amber Meriwether | Catherine Mesner | Carles Monterrubio, PhD | Neal Muni | Joseph Murphy| Jean-No?l Pellegrin | Roydon Price | Mousumi Sannigrahi, PhD MBA | John Tagliamonte | Po-Jen (Will) Yen You enrich this program and make a positive impact on our participants: DoriNano, Hestia Therapeutics, Koi Biotherapeutics, Nucyrna Therapeutics, and Sphinxion Therapeutics. If you're interested in sharing your expertise with a future MassBioDrive cohort, apply to become a mentor here: https://lnkd.in/e7Mg6vwK
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Non-stop progress in translating our technology! https://lnkd.in/eu-eYDuT
It was such a great journey for DoriNano to be a MassBio Drive cohort company, along with other amazing companies @Sphinxion, @koi, Nucyrna Therapeutics, @Hestia. The 10-minute Demo Day pitch presentation was too short to express my gratitude thoroughly. I appreciate the thoughtful organization of all the events by Nikki Taylor Seiler, MHA, Caroline Pepek, and Tiffany Patel from MassBio. Thank you for allowing the participation of our lab members Hawa Dembele, Giorgia Isinelli Qiancheng Xiong and Su Hyun Seok in the training program. They all learned a lot. Our mentors were so dedicated to offering their selfless support to us. Not only did they never miss a mentor meeting, but many of them also provided 1:1 sessions. Sincere gratitude to Arthur Hiller, Dominic McDonald, Catherine Mesner, Mathias Cousin, Michael Boss, Po-Jen (Will) Yen and Elizabeth Wood. All the working sessions were great! We learned a lot from the videos and Q&As. We appreciate all the contributors Browne Consulting, WSGR, Thermo Fisher Scientific, KPMG, and Xontogeny. The panel discussion contribted by professionals from Johnson&Johnson, Novartis and Merck for BD partnering was super helpful. I can’t wait to see all our fellow entrepreneurs' continued success. It’s great to know Julie Saba, Anita Scheuber, Hamid Mahini, @Mohammad Rashidian, Damon (Feng) Wang, PhD, Biren Shah and become friends. Appreciation to the great photographer as well John Wilcox. Graduation from MassBio Drive, a new journey has started!
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We’re excited to pitch at the MassBio 2024 Align Summit w/ insights by @McKinsey & @LocustWalkPtrs. Register for a day full of partnering opps. w/ investors, panels & pitches from presentations from early-stage #biotech and emerging AI/ML companies. Reserve your spot and see you there https://lnkd.in/ezhrkF8B #AlignSummit24, We can't wait to share our discoveries at DoriNano with you.
2024 Align Summit - MassBio
https://www.massbio.org
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Our paper published in Nature Nanotechnology marks a significant milestone and signals a new beginning for us. Our goal is to effectively translate our discoveries into clinical applications that will directly benefit patients at DoriNano. We would like to extend our heartfelt gratitude for the invaluable business support provided by Wyss Institute at Harvard University.
Effective cancer vaccines also need to effectively engage a patient’s immune system. Now, Wyss researchers have used the DoriVac vaccine platform to create DNA origami-based nanostructures in the shape of nanometer-sized squareblocks that, on one face, present immune cell-activating adjuvant molecules with nanoprecise spacing and on the other face tumor antigens. In preclinical models, these DoriVac vaccines allowed a highly beneficial activation of immune cells, and led to much stronger anti-tumor responses than those produced by free adjuvant and antigen molecules. #CancerVaccine #DNAOrigami #DNA #Nanotechnology #CancerResearch #CancerTherapy #Immunotherapy Yang (Claire) Zeng https://lnkd.in/eD67FWQv
DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy
https://wyss.harvard.edu