Digital Pathology Today

SEASON 1, EPISODE 11: Working Together for a Better Workflow One of the buzz words associated with digital pathology is, of course, "workflows." In this episode of Digital Pathology Today, we will examine the components and considerations of workflows that a pathology group has to consider before implementing a #digital #pathology system. We will discuss interoperability and how pathology groups and hospital systems can maximize their investment and future- proof the investment to protect against downside along the way. We are talking with Dr. Mark Lloyd, the founder of Inspirata, who had a vision of developing and delivering innovative solutions to transform the #cancer experience for doctors and patients.

SEASON 1, EPISODE 10: Digital Pathology in Drug Development Our guest this episode is Elizabeth DVM, DABT, ERT, Digital ToxPathologist, who focuses on pre-clinical #research, histopathological evaluation, due diligence, digital pathology as well as quality assurance expertise. This episode we will look at toxicological pathology and the role of #digital #pathology in drug development. We will discuss the job of a toxicological pathologist and how it has shifted during COVD-19. We will also look at the use of artificial intelligence in drug development.

SEASON 1, EPISODE 8: The Global Practice of Digital Pathology Dan Milner, MD, MSc, Chief Medical Officer of the American Society for Clinical Pathology (ASCP), has been heavily involved in pathology capacity building in many countries and, most notably, led the team that built anatomic pathology laboratories in Rwanda and Haiti for advanced cancer diagnostics. Before joining ASCP, Dr. Milner spent 10 years at Harvard where he was the primary lead for infectious disease consultations in AP and CP; and was the recipient of numerous research grants and the author of over 100 publications. We discuss the global practice of pathology - challenges and opportunities in implementing #laboratory systems in both the developed and developing world. We seem to be at a unique position to take advantage of improvements in technology and #digital pathology to add enormous value to the lives of the doctors and patients we serve as pathologists. We talk about what the #future holds for the profession of #pathology. What is the truth about reports of the much talked about impending shortage of pathologists? Will technology make much of what we do obsolete? Who will be the beneficiaries of new applications in artificial intelligence? Will pathologists become the conductors of the orchestra of medicine?

SEASON 1, EPISODE 7: What is Informatics? Our guest this week is Dr. J. Mark Tuthill, head of Pathology informatics at Henry Ford Health System. Dr. Tuthill is member of the College of American Pathologists (CAP) Education committee, the American Society for Clinical Pathology (ASCP) Informatics Council and the Association for Pathology Informatics leadership council. He has extensive experience in: anatomic and clinical pathology laboratory information systems, digital imaging systems for pathology practice, computer networking, mobile computing networks, and computer-based education. We’re discuss informatics – what exactly is informatics and what does it mean in the context of digital pathology? How will #digital #pathology systems be integrated with #laboratory information systems and how does this differ from the analog model? What will workflows look like in digital pathology? What are the complexities? What are the dangers? and what are we most likely not thinking about? And of course, what are the barriers we face in making this all work?

SEASON 1, EPISODE 6 Our guest this week is Dr. Joe Lennerz, Associate Chief of #Pathology and the Medical Director of the Center for Integrated Diagnostics (CID) at Massachusetts General Hospital (MGH). He oversees all aspects of the clinical laboratory service that supports personalized #medicine at MGH. He was the principal investigator of the first #FDA instrument precision study for the first whole slide scanning system. We're talking about Regulatory matters in #digital pathology, the various regulatory bodies at play and the alphabet soup of regulation such as CLIA, College of American Pathologists (CAP), FDA, GDRP and so forth. What is the 21st century cures act and how does it impact digital pathology? And many folks may be surprised to learn about new initiatives such as the Digital Health Center of Excellence at the FDA, designed to spur innovation. We’ll learn about the Alliance for Digital Pathology - A regulatory science initiative to harmonize and standardize digital pathology processes to speed up innovation to patients. In the past it's been tempting for many of us to think of regulation as a burden but is this mode of thinking outdated? By proactively forming partnerships with regulatory bodies will we actually be able to spur innovation and advance the state of the Science?

Dr. Matthew Hanna is Director of Digital #Pathology Informatics and breast pathologist at Memorial Sloan Kettering Cancer Center. He serves as a member on the College of American Pathologists (CAP) Informatics Committee as well as an editor for the Journal of Pathology Informatics. We will be discussing his experience in the digital pathology program at Memorial Sloan Kettering as well as recent advances in digital sign out. What is the current status #digital sign out - from a practical as well as #regulatory standpoint? What obstacles and resistance have we faced in remote sign out? And of course, what are the implications of the global COVID-19 pandemic? Were pathologists ready for remote sign out? What regulatory barriers came down to facilitate adoption. And which - if any - of these gains will become standard practice once the pandemic is over?

SEASON 1, EPISODE 3 Ajit Singh has had a vast variety of experiences in #digital #pathology as well as digital #radiology - in both operations and venture capital. He was President and CEO at BioImagene, a digital pathology company acquired by Roche, and CEO of digital radiology and medical informatics at Siemens Healthineers. He is a partner at Artiman Ventures, focusing on early stage Technology and life sciences investments. Dr. Singh also serves as adjunct professor at the Stanford University School of Medicine, and is on the Board of Trustees of the AACR. He joins us to talk about similarities and differences between the two visually based diagnostic specialties, pathology and radiology, challenges and opportunities as it applies to the global workforce shortage of pathologists in both the developed and developing world , as well as practical applications of artificial intelligence in digital pathology, and why the future might be here sooner than you may think.

SEASON 1, EPISODE 2: The evolving Role of #Digital #Pathology in Personalized #Medicine What has pathology, as a field, done well, in terms of providing tools and solutions to assist clinicians and patients in individualizing treatment options? What opportunities are there for change or improvement amidst, the massive growth and opportunity in the field of personalized medicine. Will our expanding capabilities in image analysis and the promise of artificial intelligence enable us to create new and powerful tools to diagnose disease and guide therapy? Have we finally turned the corner in incorporating #diagnostics into large prospective randomized trials which will allow us to develop and validate powerful tools to refine our prognostic and predictive capabilities? Does image analysis and the ability to Multiplex open up a whole new world of possibilities to create more powerful tools than we ever imagined? And what does the future hold? Anthony Magliocco MD has had a career spanning over 30 years and is an internationally recognized expert in developing and deploying advanced diagnostics to help cancer patients. Prior to founding Protean BioDiagnostics, he was chair of Pathology and Executive Director of Esoteric Laboratory Services at Moffitt Cancer Center. In addition, he served as Scientific Director of Moffitt Cancer Center Tissue Core and founded new fellowships in #molecular diagnostics as well as digital image analysis.

SEASON1, EPISODE 1 In this special first episode we will be talking with Liron Pantanowitz of the University of Pittsburgh about where #digital #pathology has been over the course of the past 20 years, seminal developments and advances in whole slide image and image analysis. We will discuss why it is taking so long for the full scale adoption of digital pathology in the clinical setting. In addition, we will examine the parallels and differences between the specialties of pathology and radiology, the benefits of switching to a fully digitized system, and what are the practical considerations of going digital. We will also touch on regulatory concerns, the current state of #AI applications, recent acceleration during the COVID-19 pandemic and how Dr. Pantanowitz sees the field evolving over the next 10 years and beyond.

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