Define Ventures

97% of clinical data goes unused. That’s 50 million gigabytes a year — locked away in EMRs, buried in notes, lost to complexity. To extract insights, health systems today rely on teams of clinicians manually reviewing charts. It’s slow, costly, and inconsistent. Layer Health is changing that. Their AI platform reads and interprets medical records with clinician-level understanding — and does it in hours, not months. This is what clinical inference at scale looks like. Most healthcare AI tools focus on narrow use cases, but Layer is different. They're enabling health systems to extract meaningful insights from messy, unstructured medical data with clinician-level accuracy. It’s a platform that makes clinical data understandable — and actionable. We’re thrilled to lead their $21M Series A and support them as they build the foundation for smarter, faster, more efficient healthcare. https://lnkd.in/g_hT7mtT

Marit Health is bringing radical transparency to clinician compensation. It's long overdue, which is why we're proud to lead their seed round and closely partner with them in this next chapter. Despite being some of the most in-demand professionals in the country, clinicians have shockingly little insight into their own worth. Marit Health is changing that — today, 12,000+ doctors, PAs, and NPs use Marit to compare real-world pay, benefits, call schedules, and more. It’s fast becoming the go-to resource for clinicians navigating career decisions. For employers, this data unlocks better recruiting, smarter retention strategies, and a path to rebuild trust with the clinical workforce. In a system where 1 in 5 doctors are planning to leave the field, Marit is building something essential: trust and transparency. This is a win-win model — and we're proud to partner with this team. https://lnkd.in/ggWY-Mk9

We're proud to be part of NVIDIA's healthcare and life sciences startup ecosystem, partnering closely together to push the boundaries of what's possible. #GTC25

Building a thriving workplace culture isn't about implementing flashy perks or benefits. It requires intentional strategies at every stage of the employee lifecycle - from hiring to onboarding, development, and retention. By creating transparent processes, setting clear expectations, listening to employees, and taking decisive action, you can build a workplace where talented people want to stay and contribute their best work. This guide from our head of people Karsten Vagner shares practical insights on creating a workplace where people thrive, with a special focus on the unique factors that health tech companies face. https://lnkd.in/gbW_6Yt8

In the latest edition of our Defining Healthcare newsletter, we cover... *What every AI founder needs to know before pitching potential customers *Our take on the next generation of health tech companies poised to go public, including Hinge Health *Healthcare AI's potential, according to Anthropic co-founder & president Daniela Amodei *Why we're so excited to have Carolyn Magill join our team as venture partner *Sage advice from our head of people Karsten Vagner on how to ensure your team knows how to hit their goals ...and plenty more. If you'd like to be on the list for the next edition, sign up here. https://lnkd.in/gmnvYdRC

Most VCs think people strategy = hiring great talent. But hiring alone isn’t enough — scaling teams and building a strong culture is what sets successful startups apart. Founders should look for investors who help them develop leadership, align their teams, and scale their culture — not just make hires. Our Head of People Karsten Vagner dives into what founders should be asking of their investors and ensure they go beyond recruiting and truly help them build for scale. https://lnkd.in/gAAyGsbz

We’re thrilled to welcome Carolyn Magill to Define Ventures as our newest Venture Partner! Carolyn is a seasoned healthcare leader and two-time CEO, most recently joining us as CEO at Aetion. Our team has had the privilege of closely partnering with Carolyn as a Define Advisor for many years, and we're confident her deep expertise, particularly in data and AI applications within the pharmaceutical landscape, will be invaluable to our partner companies. We recently sat down with Carolyn to learn more about why she decided to join Define, what excites her about the health tech industry today, and what she's learned throughout her career journey. https://lnkd.in/gYBZ_dvG

Blake Madden we'd agree with your hunch!

Our team is reflecting on another engaging AI forum with our close partners at leading providers and payers — this time at #ViVE25. Thank you to our co-hosts Gurmeet Sran, MD, MS at CommonSpirit Health; Patrick McGill, MD MBA at Community Health Network; and Bradley Crotty MD MPH at Froedtert Health for leading engaging conversations about priority use cases in AI today. We're already looking forward to the next one!

Payers and providers are approaching AI with as much pragmatism as enthusiasm, with the vast majority (73%) having established AI governance committees. These committees play a critical role in aligning AI initiatives with organizational values and fostering trust. They help to ensure AI adoption aligns with core values like patient protection, data privacy, and workforce trust — a balancing act that can be challenging. For founders selling AI solutions into these large healthcare organizations, it's critical to anticipate and address the concerns of AI governance bodies by proactively mitigating risks related to safety and data policies. Read our full report linked in the comments — based on extensive research with C-suite leaders and senior executives from over 60 payer and providers and chock full of valuable insights for entrepreneurs.