CytoTronics

Say hello to CytoTronics.? We’ve adopted a cool new look inspired by the energy and passion we have for transforming cell biology as you know it.??https://cytotronics.com

Missed our last few data drops? You can now explore the latest applications of Pixel electrical imaging technology in our new video library. Our growing collection highlights Pixel's remarkable versatility, featuring real-time, cellular-resolution data from various cell types in both 2D and 3D: https://hubs.ly/Q038tFty0

Human umbilical vein endothelial cells (HUVECs) are a preferred #invitro model of endothelial cells, used to study vascular processes like angiogenesis, inflammation, and tissue repair. HUVECs are also used to study the integrity of the endothelial tissue barrier, which regulates the exchange of biomaterials between the bloodstream and surrounding tissues. Examining how these cells proliferate and from barriers is critical to understanding pathological and developmental processes in #vascularbiology. In this case study, we use Pixel electrical imaging to monitor in vitro HUVEC behavior in real time, including responses to barrier modulations. Download the full case study to learn more: https://hubs.ly/Q037q-Wm0 #cellbiology #invitrobiology #endothelialcells

Sensitive detection of cell death in physiologically relevant in vitro models is critical to improving CAR-T cell therapies. With single-cell resolution, Pixel electrical imaging allows you to closely monitor interactions between T and tumor cells, including changes in cell morphology before death. Here, dying cells with altered morphologies are visible in green and blue. In this experiment, HeLa-CD19 cells were incubated with CD19-targeting T cells from ProMab Biotechnologies, Inc. for 72 hours. The left panel shows untreated cells, while the middle and right panels are seeded with 1:6 and 1:10 CAR-T:tumor cells at 24 hours, respectively. Cell death is visible even at low CAR-T:tumor cell ratios. #CARTcells #immunooncology #TcellTherapy

Endothelial cells form a selectively permeable barrier in vascular tissues that regulates the exchange of materials like ions, nutrients, and immune cells between blood vessels and the surrounding environment. Altering the permeability or structural integrity of this barrier can lead to conditions like inflammation and cardiovascular disease. In this application note, we show how Pixel electrical imaging can capture real-time functional changes in an #invitro model of the human coronary artery endothelial barrier with exceptional resolution. Download the full app note to learn more: https://hubs.ly/Q035_rVx0 #cellbiology #invitrobiology #diseasemodels

How do CAR-T cells attack tumors in real-time? Pixel electrical imaging captures the dynamic interactions between T cells and tumor spheroids, revealing both structural changes and immune cell activity. In this experiment, HeLa-CD19 spheroids were incubated with CD19-targeting T cells from ProMab Biotechnologies, Inc. for 72 hours. The left panel shows an untreated spheroid growing over time, while the right demonstrates CAR-T cells reducing the tumor mass within 24 hours after their addition. Pixel enables visualization of T cell movement as well as their impact on the tumor microenvironment. #CARTcells #immunooncology #TcellTherapy

Primary endothelial cells are critical to modeling vascular pathologies in a variety of diseases, such as cardiovascular disorders and metastatic cancers. Capturing variations in these cell populations across individual donors is crucial to predicting efficacy of targeted therapies. In this case study, Pixel electrical imaging was used to monitor functional differences in human coronary artery endothelial cells (HCAECs) with varying donor and cellular characteristics. The resulting multiparametric data provide key insights for enhancing the clinical relevance of in vitro cellular assays and models. Download the full study to learn more: https://hubs.ly/Q0355vYt0 #diseasemodels #cellbiology #invitrobiology

Pixel electrical imaging lets you observe the motility of endothelial cells in real time. BrainXell, Inc. #bloodbrainbarrier #cellbiology #livecell #SLAS2025

Pixel's high sensitivity and spatial accuracy let you monitor the formation of cell junctions and tissue barrier (shown here in deep blue) in endothelial cells. With Pixel 96- and 384-well microplates, you can also test the barrier's response to a range of molecules. BrainXell, Inc. #bloodbrainbarrier #livecell #cellbiology #SLAS2025

Catch us on the last day of #SLAS2025 at booth 2928 to learn how we are transforming #cellbiology discovery, including glimpsing exciting data from our collaborations with Axol Bioscience Ltd., BrainXell, Inc., and Yokogawa Life Science.