Cyagen

#bignews ????????????? ???????? ???????????????? ???????? ????????-????? ?????????? ???????????? ???? ????????????! Unlock the potential of cutting-edge humanized mouse models to elevate your research in rare and ultra-rare diseases, ophthalmology, neurology, and oncology. Here's why you should apply: ? ?????? ?? ???????? ???????? ???? ?????????????????? ????????:?Valued at $76,000. ? ?????? $????,?????? ?????? ???? ???????????? ????????????????:?Perfect for investigating clinical mutations. ? ???????????????? ????????????????????:?Leverage our TurboKnockout-Pro tech for superior humanization. Focus Areas: ? Ophthalmology ? Neurology ? Oncology ? Rare & Ultra-rare Diseases ???Apply Now:?Submissions are open on a rolling basis, so early applications have an advantage. ?? Application here: https://lnkd.in/gE6jdpA5 Join us in advancing gene therapy research with these state-of-the-art models! #ResearchGrants #GeneTherapy #HumanizedModels #BiomedicalResearch #HUGOGT #cyagen #biotechnology #biotech

?? Exciting News! Cyagen's Custom Cell Model Price Match Campaign is Here! ?? Looking for custom cell models at the best value? Cyagen is committed to making advanced research more accessible by matching competitor pricing on custom cell line development! ?? ?? What We Offer: ? Custom iPSC, immortalized, and primary cell models ? Gene knockout, knock-in, and overexpression modifications ? Industry-leading quality & expert scientific support ?? How It Works: Simply provide a competitor’s quote, and we’ll match it—ensuring you get top-tier models at the best price. ?? Limited-Time Offer – Act Now! Learn more & request a free expert consultation: https://lnkd.in/gggxPFb8 #Cyagen #CellModels #LifeSciences #Biotech #StemCellResearch #GeneEditing

Science headlines—what’s really going on with "trans mice"? ???? With recent discussions putting genetically modified mouse models in the spotlight, it's a great time to revisit what these studies actually mean for biomedical research. Our video provides a solid explainer on how scientists use genetic modifications to study sex development, hormone function, and their broader implications for human health. At Cyagen, we understand the critical role genetically engineered models play in advancing research—from rare diseases to regenerative medicine. As science continues to push boundaries, it's always fascinating to see where these discussions lead! ?? https://lnkd.in/gMAQwCNg #transgenicmice #GeneticResearch #MouseModels #ScienceExplained #transgenic

#weeklynewsletter ?? Innovative Research in Hyperuricemia and Gout Hyperuricemia, marked by elevated uric acid levels, poses significant health risks, including gout and kidney stones. To support drug development, Cyagen has introduced the?B6-hXDH humanized mouse model, designed to replicate human uric acid metabolism by incorporating the complete human XDH gene, replacing the native mouse version. ???Key Benefits: ??Accurate Modeling:?Ideal for evaluating xanthine oxidase inhibitors (XOIs) and RNA-based therapies. ??Targeted Research:?Provides a platform for developing safer alternatives to current medications like allopurinol and febuxostat. ??Preclinical Advancements:?A valuable tool for advancing our understanding of hyperuricemia and gout. With hyperuricemia affecting over 1.1 billion people globally, innovations like the B6-hXDH model are crucial for discovering effective treatments. #Hyperuricemia #Gout #Research #Cyagen #DrugDevelopment #HUGOGT #scienceandtechnology #researchmatters #researchimpact #biotech

??? Be Part of the 2025 Cyagen Global Partnership Forum! Join us for an exclusive event where global leaders in biotechnology and preclinical research come together to discuss the latest advancements in drug discovery and biomedical science. ?? When: February 26-28, 2025 (PT) | February 27 - March 1, 2025 (Beijing Time) ?? Where: Runxi Hotel, Taicang, Jiangsu, China Why You Should Attend: ? Network with thought leaders and innovators in the field. ? Explore pioneering models like HUGO-GT? humanized mice. ? Discover AI-powered tools for rare disease research and antibody sequencing. ? Get an inside look at Cyagen's cutting-edge facilities. ?? Limited space available! Register now to secure your spot: https://lnkd.in/gXW7B9bZ #globalforum #biotechnology #HUGOGT #Cyagen #biotech #preclinicalresearch #humanizedmice #AI #antibodydiscovery #global #network

?? Transforming Eye and Cancer Research with VEGFA Mice! Discover how VEGFA mice, developed by Cyagen, are enhancing drug testing accuracy and shaping treatment strategies. Vascular endothelial growth factor A (VEGFA) is crucial for blood vessel formation and impacts tumor growth and retinal diseases like age-related macular degeneration (AMD). These innovative humanized and transgenic models allow for precise therapy testing, mirroring human biology. Notably, the RB6 VOM I model maintains normal retinal structure, which is essential for effective research. With new VEGFA-targeting drugs on the horizon, these models are pivotal in advancing treatments for AMD and various cancers. Join the conversation on the future of VEGFA research! ? ?? Learn more about VEGFA mice: https://lnkd.in/grV3H-yG ?? For more YouTube videos please visit here: https://lnkd.in/gGJFKfyX #VEGFA #Research #Ophthalmology #Oncology #DrugDevelopment #HUGOGT #Cyagen #biotechnology #biotech #scienceandtechnology

#researchmatters ? Recent research on CELL from the University of Geneva reveals that tumor-infiltrating lymphocytes, especially CD8+ T cells, follow circadian rhythms that influence tumor growth and the effectiveness of immunotherapy. By timing treatments like CAR-T and immune checkpoint blockade, efficacy can be enhanced. Time-of-day T cell signatures have even been shown to predict survival rates in melanoma patients and response to anti-PD-1 therapy, demonstrating the potential of circadian dynamics to improve clinical trials and patient outcomes. Read more here: DOI:?10.1016/j.cell.2024.04.015 ?? At Cyagen, we’re dedicated to advancing gene-edited cells and animal models. Our experienced team and robust technology platform provide cutting-edge solutions for target gene expression regulation, with a focus on CAR-T and cell therapy research. We offer an extensive catalog of thousands of cell and mouse models for tumor immune research, alongside preclinical pharmacology evaluation services for pharmaceutical companies, biotech firms, research institutes, and hospitals worldwide. One example is our NKG mice model, a severe combined immunodeficiency (SCID) model, which allows for human immune system reconstruction and the creation of various CDX models. ?? Learn more about our Cell & Animal Models for Immune-Oncology and Cell Therapy: https://lnkd.in/gG2XjxGs ?? Learn more about NKG mice: https://lnkd.in/gjQsBfnc #CancerResearch #Immunotherapy #GeneEditing #CART #CellTherapy #PreclinicalResearch #AnimalModels #Pharmacology #Cyagen #HUGOGT #biotech

?? Our Weekly Flash Sales are back for the new year! This week (Feb 17), enjoy amazing savings on mouse models to boost your research. Don’t miss out on these incredible deals! https://lnkd.in/gFSKCDqs Explore our options and secure your models today! ?? #weekly #flashsale #knockout #mousemodel #mice #saletips #HUGOGT #biotechnology #Cyagen #biotech

#mondayvibes Planning a trip? ?? Here’s a handy tip for packing your cosmetics like a pro! ?? Image from Sketching Science #lablife #mondayvibe #phdlife #comics #traveltips #scientists #biotechnology

#weeklynewsletter ??Is Your Love Life Written in Your DNA? ?? In this week's newsletter, you will find the answers. Science just revealed how your genes secretly control: ?? Who you find?irresistible?(blame MHC "scent genes") ?? Whether you’re a passionate adventurer (DRD4 gene at work) ?? Your bonding style (thank OXTR, the “cuddle hormone” gene) Learn more about our research models here: https://lnkd.in/gse5U4UK #valentinesday #scienceandlove #animalmodels #mousemodels #biotechnology #Cyagen #biotech