Creative Biogene

Virus-like particles (VLPs) have been favored for RNA delivery in recent years as RNA in general has better biosafety than DNA, and different types of RNAs have been delivered with VLPs. VLPs are considered to be a promising RNA delivery vector with multiple advantages. Creative Biogene provides customers with comprehensive solutions for the development of virus-like vectors based on our expertise in the structure and design modification of VLPs, providing a promising platform for efficient targeted RNA delivery. https://lnkd.in/gsCWpzQU

Creative Biogene offers a comprehensive suite of miRNA services designed to accelerate your research and contribute to groundbreaking discoveries. With our advanced technologies, cutting-edge equipment, and highly experienced experts, we provide tailored miRNA services that meet your needs in miRNA profiling, screening, synthesis, and functional studies. https://lnkd.in/ggGzdPBM

At Creative Biogene, we offer various custom library construction services, including cDNA libraries, genomic libraries, BAC libraries, mutant libraries, shotgun libraries, and more. Our team is equipped with advanced technologies and extensive experience, allowing us to provide high-quality library construction services to meet diverse research needs. https://lnkd.in/g67NVHT3

Creative Biogene provides off-target analysis services with over 10 years of gene editing experience. Our long-read sequencing technology, based on SMRT (Single Molecule Real-Time) technology, provides an advanced solution for off-target effect assessment, ensuring both accuracy and reliability.?https://lnkd.in/gtirdmAc

Phagemid vectors are versatile tools derived from both coliphages and plasmids, featuring a plasmid replication origin for double-stranded DNA isolation and a phage replication origin for single-stranded replication. Creative Biogene offers a range of phagemid vectors for diverse research needs, including protein-protein interaction studies, enzyme inhibitor screening, and ligand screening.?https://lnkd.in/gvyh-Tep

Creative Biogene offers a comprehensive suite of services for the design, synthesis, and optimization of 2'-O-C16-siRNA conjugates tailored to meet your central nervous system (CNS)-target delivery needs. Our service covers everything from initial design to large-scale synthesis, with a strong focus on optimizing delivery and targeting efficiency. https://lnkd.in/dgxNpR6y

At Creative Biogene, we harness CRISPR systems' unprecedented precision and versatility to drive the boundaries of gene research and therapeutic applications. Our complete CRISPR services include sophisticated solutions such as sgRNA design and validation, off-target efficiency analysis, gene editing cell line production, gene editing animal model development, CRISPR library screening, and RNA editing. We are devoted to offering tailored solutions to our client's diverse demands in genome engineering and functional genomics research. https://lnkd.in/g8Rd9Pxb

Building on years of expertise in oligonucleotide chemistry, Creative Biogene offers a comprehensive suite of services for the synthesis of GalNAc-conjugated oligonucleotides. From initial design to large-scale production, our services are tailored to support the successful development of GalNAc-based oligonucleotide drugs. https://lnkd.in/gYcXwATA

Creative Biogene's reporter AAVs include high-titer production using proprietary HEK293 manufacturing platforms, extensive quality control testing, and custom packaging capabilities. Fluorescent reporter options such as GFP, RFP, mCherry, and luciferase reporters provide sensitive readouts of transduction efficiency and gene expression. The AAV reporter particles represent powerful tools for tracking virus biodistribution, optimizing delivery conditions, and studying cell biology and gene function. https://lnkd.in/g-4_HTD9

Creative Biogene offers vast knowledge and experience in improving CSISPR efficiency and developing applications. Our complete CRISPR services include sophisticated solutions such as sgRNA design and validation, off-target efficiency analysis, gene editing cell line production, gene editing animal model development, CRISPR library screening, and RNA editing.?https://lnkd.in/g8Rd9Pxb