Capstan Therapeutics

We are proud to be recognized among this year’s?Endpoints News?11 awardees! Thank you to all our Capstaneers for your creativity, collaboration, and commitment to our mission to multiply the therapeutic possibilities for patients. We share this honor with all of you! #Endpoints11

We are looking forward to #ACR24 in November where Capstan will debut key preclinical data on CPTX2309, our lead?in vivo?chimeric antigen receptor T cell (CAR-T) candidate. ? Presentation details: - ORAL PRESENTATION: Effective Engineering of CD8+ T Cells from Autoimmune Disease Patients Utilizing a CD8-Targeted Lipid Nanoparticle Encoding an Anti-CD19 CAR mRNA (CPTX2309) - POSTER: Profound B Cell Depletion and Repopulation with Predominantly Na?ve B Cells in Non-Human Primates Achieved Through a Novel?In Vivo CD8-Targeted Lipid Nanoparticle mRNA CAR - POSTER: A Novel Product Candidate (CPTX2309) for In Vivo mRNA Engineering of Anti-CD19 CAR T Cells Utilizing Novel CD8-Targeted Lipid Nanoparticles More in today’s release: https://lnkd.in/esaXyhgF ? American College of Rheumatology

Next month Capstan will participate in investor conferences hosted by Goldman Sachs and Leerink Partners. More in today’s press release: https://lnkd.in/eVMmPASX

Go Padres! Team Capstan had a fantastic time cheering on our favorite baseball team at Petco Park this past summer.

Our CSO Adrian Bot, M.D., Ph.D. spoke with Asher Mullard of Nature Reviews Drug Discovery about how Capstan is innovating in the field of in vivo CAR T.?Capstan’s goal is to efficiently reprogram T cells through our CellSeeker? platform, a disruptive technology to make CAR-T therapy scalable, tunable, and potentially safer for patients suffering from autoimmune disorders. https://lnkd.in/gPphT5gx

Next month Capstan management will attend the?Morgan Stanley?22nd Annual Global Healthcare Conference. More in today’s release: https://bit.ly/3WZpTm9

Team Capstan is making the most of the beautiful San Diego summer by enjoying quality time outdoors with colleagues and families!?Our recent annual Summer Family Picnic at Park Commons San Diego was a fantastic success, featuring live music, team-building activities, and delicious local cuisine. ? We cherish these opportunities to connect outside the office, reinforcing our mission to cultivate an inclusive and vibrant culture so that we can continue to do our best work for patients. Big thanks to Alexandria Events San Diego and Exos for helping us organize such a successful event! ? #CapstanTx #LifeScienceCulture??

Capstan Co-Founder?Carl June?is a pioneer in CAR T-cell therapy. In this?Forbes?article by?Juergen Eckhardt, Dr. June delves into the vast potential that CAR T holds for an expansive amount of therapeutic applications, as well as the potential?safety, efficiency, and cost benefits of in vivo engineering.? ? Capstan is leveraging the power of in vivo CAR T to generate transformative therapies with?applications across a broad range of disease areas. ? Read more here: https://lnkd.in/eg7piMSw

How is Capstan advancing the game-changing field of?in vivo?CAR-T? Our CMO Ramin Farzaneh-Far, M.D., spoke with PharmaVoice about the potential to retain the positive benefits of CAR-T but eliminate the drawbacks of autologous and allogeneic approaches, bringing the benefits to more patients and new indications?including #autoimmunedisorders. The article also discusses the technical considerations for developing?in vivo?CAR-T therapies, including Capstan’s targeted lipid nanoparticle delivery. Don’t miss this timely conversation: https://lnkd.in/gM9zTPxi

At Capstan, commitment is one of our core values – commitment to patients, colleagues, and our families. Last month, we had the pleasure of hosting Bring Your Kids to Work Day, where Capstaneers had the opportunity to introduce their children to what we do at Capstan and?our focus on improving the lives of patients.?? ? The kids had the chance to visit our lab space, learn about our equipment, participate in a pipetting competition, and more. We also held an educational session that dove deep into our science and approach hosted by Co-Founder and Vice President of Research,?Haig Aghajanian, Ph.D.?It was an exciting day, jam packed with activities that provided valuable learning opportunities for the kids of Capstan.? ? Thank you to everyone who participated and made the event such a success!?#CapstanTx #LNP #mRNA #LifeScienceCulture #KidsAtWork