BU Pulmonary Center

?? ?? New article alert! ?? ?? Thrilled to share my very first publication as the co-lead author at BU Pulmonary Center on complement and hookworm infections in the lungs !!! In this brief report, we dive deep into one of the most important neglected tropical diseases, i.e. the hookworm disease, and explore the impact of C5aR1 signaling in neutrophils during Nippostrongylus brasiliensis infection in mice. Thanks to my collaborators, supervisor Markus Bosmann and BU Pulmonary Center for their contribution and support ? We'd love to hear your thoughts ?? #complement #C5a #hookworm #infection #lung #nippostrongylus #neutrophils #helminth #nematode #parasite #immunology #inflammation #research #science #publication #briefreport #nosmallvictories

Happy to share our newest research, published in 'Frontiers in Immunology' Journal. Our findings highlight the impact of C5aR1 signaling in neutrophils during hookworm infection uncovering an unexpected downside of complement activation in parasitic infection. #Nippostrongylus_brasiliensis, #Complement_system BU Pulmonary Center, Jason Noon

It was a pleasure and an honor to host Jeopardy (as Trebek) at the Pulmonary Immunology Group (PIG) meeting today at the BU Pulmonary Center! Thank you to everyone who helped out and participated! Congradulations to the "Hippo" (pathway) team of Elise Armstrong, Michael Vannini, and Bob Varelas who won!

Interested in learning about the CReM's new collaboration with GSK? Read about it in News Medical linked below:

Check out this article from The Brink about the CReM's new collaboration with GSK! Click on the link to learn more:

Dr. Jingzhou Zhang, a senior pulmonary fellow, investigated the role of BMI in COPD mortality through a multi-cohort genetic epidemiology study. While both low and extremely high BMI are associated with increased mortality in COPD, the underlying mechanisms remain unclear. Using a polygenic score for BMI, Dr. Zhang and colleagues found that genetically determined BMI was positively associated with an increased risk of cardiovascular death, but not respiratory death, in individuals with COPD. A discordantly low BMI (measured BMI lower than genetically predicted) was associated with an increased risk of all-cause and respiratory mortality, after adjusting for COPD severity, suggesting its potential prognostic value for patients with COPD. This work, led by Dr. Zhang and co-supervised by Dr. George O’Connor and Dr. Michael Cho, was recently published as an original article in the American Journal of Respiratory and Critical Care Medicine. Read the whole article here: https://lnkd.in/eJD-fM9P

Help is on the way! Announcing our new CReM-GSK collaboration to harness stem cell technologies (iPSCs) for drug development to better treat pulmonary fibrosis and other chronic lung diseases!

Earlier this week, the Center for Regenerative Medicine (CReM) at BMC and Boston University celebrated their new collaboration with GSK. The teams will work together to develop cutting-edge cellular models that will inform the development of new treatments for patients with lung diseases, like pulmonary fibrosis, and pave the way for a healthier future for everyone. Thank you to Rep. John Moran for coming to learn about our innovative work! Learn more: https://lnkd.in/eDt-DEwE

Thank you Dr Sharon Chinthrajah for being our speaker at the annual Sue Kim Hanson Lecture last month!

Viviana Reyes Pinzon did a wonderful job presenting her case of LIP complicated by pulmonary MALT last night at the American College of Chest Physicians Boston City Fellows’ Conference last evening. We had a great turn out at the conference and naturally we took advantage of the photo-op!