Atomwise is revolutionizing how drugs are discovered using #AI. Our deep learning technology for structure-based drug discovery enables our pipeline of small-molecule drug candidates.? Learn more about Atomwise and how we’re changing traditional #drugdiscovery ??
关于我们
Atomwise is a preclinical pharma company revolutionizing how drugs are discovered with AI. Atomwise has strengthened its drug discovery and development expertise by expanding its Board of Directors and creating a Scientific Advisory Board (SAB). These appointments signal a critical milestone for Atomwise as the company focuses on its own internal pipeline. We invented the use of deep learning for structure-based drug discovery, today developing a pipeline of small-molecule drug candidates advancing into preclinical studies. Our AtomNet? technology has been used to unlock more undruggable targets than any other AI drug discovery platform. We are tackling over 600 unique disease targets with more than 250 partners around the world, including leading pharmaceutical, agrochemical, and emerging biotechnology companies. Atomwise has raised over $174 million from leading venture capital firms to advance our mission to make better medicines, faster. We’re at a critical time in history where our need for new kinds of medicines is greater than any time in human memory. Fortunately, we can leverage advancing technology and scientific breakthroughs to accelerate discovery. New data, new algorithms, new compute platforms lift all of us, enable our work on the hardest of problems, empower us to invent and create, and ultimately save one billion lives. Join us: www.atomwise.com/careers
- 网站
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https://www.atomwise.com
Atomwise的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- San Francisco，California
- 类型
- 私人持股
- 创立
- 2012
- 领域
- Machine Learning、Artificial Intelligence、Drug Discovery和Computer Aided Drug Design
地点
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主要
获取路线
717 Market St.
Suite 800
US，California，San Francisco，94103
Atomwise员工
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Ed Kawashiri, C.P.M., MBA
Director of Procurement & Facilities at Atomwise
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Robert Mittendorff, MD, MBA
General Partner and Head of Healthcare at B Capital
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Michael Wimpee
Versatile and Experienced Engineer, SRE/DevOps, Manager, and Technical Leader
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Gavin Hirst
Drug Discovery Executive Leader | Medicinal Chemist | Team Builder
动态
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Promising news for cancer research! A team from the University of Pavia, Italy, leveraged AtomNet #AI to design small molecules targeting Voltage-dependent Anion-selective Channel 1 (VDAC1), a protein implicated in various cancers. Their approach focused on immobilizing a flexible helix within VDAC1, thereby modifying a metabolite binding site and a putative protein-protein interaction (PPI) implicated in tumor cell proliferation. These VDAC1 molecular glues demonstrated dose-dependent efficacy in reducing cancer cell viability while exhibiting minimal impact on healthy cells and organoids. The research lays a foundation for future development of these molecules as potential cancer therapeutics. Read more here: https://lnkd.in/e3wp5kHd
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The verdict is in! Our proprietary AtomNet #AI platform is a viable alternative to high-throughput screening for discovering structurally novel chemical matter, regardless of the target: https://lnkd.in/ebPpWhnH In the largest, most comprehensive virtual high-throughput screening campaign of its kind, we applied AtomNet to 318 targets covering a wide range of classes. AtomNet found hits for 235 targets, averaging over seven structurally distinct bioactive compounds per target. Even more impressively, most of the targets assessed lacked any target-specific training data, with hits representing first-in-class binders to the target. Check out our publication in Nature Scientific Reports for more details: https://lnkd.in/eFcNAC3S We believe that AtomNet's ability to find novel chemical matter even for data-poor targets is a significant achievement in the field of AI #DrugDiscovery. We are grateful to our 600+ talented collaborators who contributed to this effort!
Atomwise Publishes Results from 318-Target Study Showcasing AtomNet AI Platform’s Ability to Discover Structurally Novel Chemical Matter
https://www.atomwise.com