Atlas of Variant Effects Alliance

Our 8th Annual Mutational Scanning Symposium is coming up! "Mapping and Modelling Variant Effects at Scale" #VariantEffect25 ??? May 21-23, 2025 ??Barcelona (or online) Register soon to receive the early bird rate! ?? https://lnkd.in/gAvatF7v

Join us on April 1st with Joyce Kang and Yiyun Rao #FunctionalGenomics #Seminar https://lnkd.in/gsTpV2AR

?? “I was at the Sanger Institute at the time the human genome was being sequenced. Over the last two decades, I have watched the astronomical improvements in sequencing technology that made this endeavour a reality. [...]In 10 to 15 years, we should be able to deliver a variant effect map for all diseases.” Sanger Group Leader David Adams is one of the co-founders of the Atlas of Variant Effects Alliance. An international collaboration, including the Wellcome Sanger Institute, the Alliance aims to map the effects of all possible variants, or changes, in our genome. Learn more about the work of AVE, here ?? https://lnkd.in/eE-kNZCK Dave is also one of the organisers and speakers at this year’s Mutational Scanning Symposium, the Alliance’s flagship event, which brings together researchers from all over the world to discuss mutational scanning technologies. ?? Want to know more about this year's event in May? Registrations are currently open ?? https://lnkd.in/dvKrxGk7 Interested in finding out more about what happens at the Mutational Scanning Symposium? In 2023, the event took place at the Wellcome Genome Campus and researchers from over 50 countries explored the possibilities of this exciting genomic method and its potential benefit for clinicians and patients. Read their insights, or check out the visual summaries, over on the blog ??? https://lnkd.in/ei63yh2A

??Nominate speakers for the Variant Effects Seminar Series! ?? Early-career scientists worldwide share research on interpreting human genetic variation. Must be a student, postdoc, or new faculty (<1 yr). Self-nominations encouraged! ?? https://lnkd.in/gCqJwTf3

?????????????????? ?????????????????? ???? ?????????????? ???????? ?????????????????????????? ???? ???????????????? ?????? ???????????????? ???????????? ???????????????????? ????????! #CCG2025 ??? ???????????????????? ??????????: ????-???? ???????? ???????? ? ?????????? ?????? ?????????????????? ???????????????????? ???? ???? ?????????? Our bursary scheme provides up to 50% off the conference registration fee, enabling you to join a global community of biodata and clinical medicine professionals for networking and knowledge exchange. ?????????? ?????? ?????????????????????????? ???????? ?????????? ????: ? Recommendations for variant classification ? Tools and resources for variant classification ? Non-coding variation and regulation ? Somatic variation ? MAVEs and functional genomics ? Population and new-born genome screening (panel discussion) Multiple opportunities to present your own research are available in the format of short talks and poster pitches, selected from suitable abstracts. ???? ???????????????? ?????????????????? ???????????????? ?????????????????????? ???????? ?????????????? ????????????????????, as this is an excellent opportunity to build your research profile, gain valuable feedback, and forge cross-disciplinary relationships. ?? ???????? ?????? ???????? ?????????????????????? ????????: bit.ly/4hz5zkS #ClinicalGenomics #GenomicsData #BigData #Curating #Genomics #VariantInterpretation #MedicalGenetics #PrecisionMedicine #Genetics #AcademicChatter #PhDChat #PhDlife #FinancialAssistance #Bursaries The Nordic Alliance for Clinical Genomics | Clinical Genetics Society | Clinical genetics and heredity | Association for Clinical Genomic Science (ACGS) | Global Alliance for Genomics and Health | GenomeConnect

Thank you to our presenters Malvika Tejura Shawn Fayer Zachary Walsh! and for everyone who was able to join us in real-time yesterday for the Variant Effects Seminar. But no worries if you missed it! Talks are now available to view on-line. ?? https://lnkd.in/gW9krvT2

Happening tomorrow at 12pm ET, make sure to tune in!

? 1st of March: deadline for abstract submissions and early bird registrations is fast approaching! Mutational scanning technologies and Multiplex Assays of Variant Effects (MAVEs) are key to variant interpretation and transform our understanding of the human genome. At the 8th annual meeting of the ‘Mutational Scanning Symposium’, experts in the fields of functional genomics, protein science, precision medicine, variant interpretation, and computational genetics came from around the world to meet, present their work, discuss new methods and provide insights on the future of this science. The conference will be a two and a half days hybrid meeting with onsite or virtual attendance. Discussions will center on a variety of exciting topics, including variant effect prediction, saturation mutagenesis, sequence/structure/function relationships and protein engineering, along with conversations about emerging technologies for functional assays and biophysical modelling. #VariantEffect25 Organised with Institute for Bioengineering of Catalonia (IBEC) by Ben Lehner FRS FMedSci Jonathan Frazer Mafalda Dias Benedetta Bolognesi and Lara Muffley Atlas of Variant Effects Alliance Sign up today: https://lnkd.in/dvKrxGk7

The 8th Annual Mutational Scanning Symposium is just around the corner! #VariantEffect25 #FunctionalGenomics #Symposium What we are looking forward to: ??? Great talks! ??? Workshops! ?? Poster session and awards! ?? Amazing community! ?? March 1st deadline for abstracts! (and for the early bird registration) for more information and to register visit https://lnkd.in/gAvatF7v

?? Mutational Scanning Symposium IMPORTANT DEADLINES ? Early registration deadline: March 1st, 2025 (discounted rate!) Abstract submission deadline: March 1st, 2025 ?? https://lnkd.in/dvKrxGk7 Institute for Bioengineering of Catalonia (IBEC) Centre for Genomic Regulation (CRG) #VariantEffect25