AMR Action Fund

Melissa Murray regularly ran 10 km?a day—until a serious infection caused her to nearly lose?a leg. She had an?invasive Group A strep?(iGAS) bacterial infection that could not be treated with standard antibiotics and suddenly needed round-the-clock care. Read more via CBC https://t.co/U3hQfjWsix #AMR

ICYMI, the Center for Global Development last week released a new report on the economic consequences of AMR and the findings are staggering. AMR increases the cost of health care by $66 billion. Under certain conditions, AMR health costs could rise to $325 billion and the global economy would be $1.7 trillion smaller in 2050. Learn more and download the full report: https://lnkd.in/eMkHcaWc

As antimicrobial resistance (#AMR) advocates and stakeholders from around the world start departing the United Nations, I’m feeling more energized and optimistic than ever that the world is waking up to - and taking action on - AMR. A few (among many) highlights from the UN High-level Meeting and week of activities include robust global support for the political declaration, the European Union’s commitment of 2.5 million Euros to support an independent panel on evidence for action against AMR, and approaching this from a One Health perspective (human, animal, plant and environment). It is imperative that we build on the momentum of this week to drive policymakers forward, particularly in G7 countries. Access and innovation are key to the fight against AMR but without appropriately-sized pull incentives, innovation will continue to falter, and we will only fall further behind on AMR.

Pleased to be back at the United Nations today for the High-Level Meeting in Antimicrobial Resistance after attending yesterday’s meeting at the UN on Fostering an Equitable Global Response to AMR, each supporting urgent action, such as that outlined in the UN Political Declaration of the High-level Meeting on Antimicrobial Resistance, to address the growing impact of AMR. The erosion of the effectiveness of antibiotics over the last decades and inadequate efforts to maintain their potency is a global threat to every individual, but especially the most vulnerable in society. We can collectively address this growing crisis IF we have the will.

A third of a million people pass through Times Square every day - more on busy days (which probably includes this week!). Amazing job by the Fleming Initiative to get this short and compelling message in front of so many eyes. I actually think so many of us stopping to take notice (and photos and videos) has also drawn attention - so if you are in NYC but haven’t yet seen it, go take a look. And please indulge me with the extra touch of pop culture (turn on your audio!)! (Song copyright: whomever owns Jackson Browne’s music)

As the UN High-Level Meeting on AMR approaches, CEO Henry Skinner spoke at a One Health Trust event about how we can create an environment for antimicrobial R&D that responds to the diverse needs of people across the world. "As we think about some of the solutions that are being proposed—pull incentives like the PASTEUR Act, and other means of bringing industry and academia into alignment, for instance—we?must think carefully about how incentives can be wisely designed so that they actually incentivize the greatest possible good." #AMR

“For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug interactions,” AMR Action Fund CEO Henry Skinner said. “These therapies are increasingly failing in patients. We are thrilled to support F2G’s team as they develop this urgently needed therapy.” Learn more about our newly announced investment into F2G, which is developing olorofim, a novel oral antifungal therapy to treat invasive aspergillosis and other invasive fungal infections. #FungalDiseaseAwarenessWeek #AMR?

The numbers in the new GRAM paper published in the Lancet show that global morbidity and mortality from drug-resistant infections represent a staggering, unacceptable, and unnecessary level of human suffering, and they underscore the importance of next week’s UN High-Level Meeting on AMR to deliver concrete action and not just platitudes. We need governments, industry, and civil society working together to address the many facets of this crisis and prevent privation caused by a lack of access to effective antibiotics. As I told the LA Times, “A continued failure of governments to meet their moral obligations to protect and care for their people, as this paper shows, will doom millions of people to needless deaths.” https://lnkd.in/eRn5eQsD

The Cancer & AMR Consortium is at the World Cancer Congress, hosted by Union for International Cancer Control (UICC), sounding the alarm on the threat that #AMR poses to people living with cancer.

A new study led by IHME and published in The Lancet found that more than 1 million people died from AMR globally each year between 1990 and 2021 and estimated that nearly 40 million people around the world could die from antibiotic-resistant infections over the next 25 years. It is imperative that policymakers act on #AMR now, including taking steps to incentivize drug developers to pursue innovative, effective, and accessible antimicrobials now and into the future. Full study: https://lnkd.in/e8XJcQ7Y And an overview of the study from Institute for Health Metrics and Evaluation: https://lnkd.in/ek8WQs8X