We are looking forward to the Piper Sandler 36th Annual Healthcare Conference taking place December 3-5 in New York City. Our CEO Michelle Werner will be presenting on how we are leveraging Alltrna’s platform, enabled by AI and machine learning, to decipher tRNA biology and pioneer tRNA therapeutics to treat thousands of diseases. Learn more: www.alltrna.com #tRNAmedicines #tRNA #rarediseases #raredisease #StopCodonDisease? #geneticmedicines #AI #machinelearning
Alltrna
生物技术研究
Cambridge,Massachusetts 7,095 位关注者
The world’s first transfer RNA (tRNA) platform company. We are unlocking the vast therapeutic potential within #tRNA.
关于我们
Alltrna is the first transfer RNA (tRNA) platform company, and our mission is to unlock tRNA biology and pioneer tRNA therapeutics to regulate the protein universe and resolve disease. Founded at Flagship Labs in 2018, Alltrna has mapped tRNA biology to systematically design tRNA medicines and encode a completely new, unifying approach to treating both rare and common human diseases driven by shared genetic mutations. Alltrna’s platform combines internal expertise and proprietary machine learning tools to unlock the entire tRNA biology space. We have an unprecedented opportunity to advance a single tRNA medicine to restore disrupted protein production, regardless of target, for thousands of diseases with the same underlying genetic mutation.
- 网站
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https://www.alltrna.com
Alltrna的外部链接
- 所属行业
- 生物技术研究
- 规模
- 11-50 人
- 总部
- Cambridge,Massachusetts
- 类型
- 私人持股
- 创立
- 2018
地点
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主要
US,Massachusetts,Cambridge
Alltrna员工
动态
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As leaders in translating tRNA biology into transformative medicines, we're proud to sponsor and present at the ???????? ???????? ???????????????????? in Kanazawa, Japan, from November 18-22. Since 1969, this biennial gathering has brought together experts to explore cutting-edge advancements in tRNA biology. We look forward to sharing Alltrna’s innovative approach in designing and delivering tRNA as a groundbreaking therapeutic modality. We will have a seminar and a poster where we will present proof-of-concept data on the ability of our engineered tRNAs to readthrough premature termination codons and restore protein production.? We are excited about what these data mean for the potential creation of universal medicines to treat diseases that share these genetic mutations, collectively referred to as Stop Codon Disease. To see more about the conference, visit: https://lnkd.in/gYRzmtHy #tRNAmedicines #tRNA #rarediseases #raredisease #StopCodonDisease? #geneticmedicines #AI #machinelearning
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Our CEO Michelle Werner will be participating in Jefferies London Healthcare Conference 2024, and sharing how Alltrna is advancing universal tRNA medicines to restore disrupted protein production, regardless of target, for thousands of diseases with the same underlying genetic mutation.? https://www.alltrna.com/ #JefferiesHealthcare #tRNAmedicines? #tRNA #rarediseases #raredisease #StopCodonDisease? #geneticmedicines
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We are thrilled to welcome Sandra Visser, Ph.D., to the Alltrna team as SVP, Head of Therapeutics Development! With over two decades of experience in quantitative medicine, drug discovery, and strategic development, Sandra is driven by a passion for accelerating novel therapies and improving patient outcomes. Her impressive background includes leadership roles at GSK, Merck, and AstraZeneca, where she and her teams made groundbreaking advancements in preclinical and clinical drug projects. Join us in welcoming Sandra to Alltrna! #tRNAmedicines? #tRNA #rarediseases #raredisease #StopCodonDisease? #geneticmedicines
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?? Spooky season fun with the Alltrna team! ?? Today, we celebrated Halloween in style with a festive brunch filled with costumes, laughs, and delicious treats. From mad scientists to monsters, our team got into the Halloween spirit—proving that we can be serious about #tRNA research and have a frighteningly good time. Happy Halloween from #TeamAlltrna! ????
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Did you know that chemical modifications on tRNAs play a key role in their structure, function, and stability? Chemically modified tRNAs have not previously been produced successfully at a scale required for preclinical development and clinical trials. To advance our first tRNA medicines to the clinic, Alltrna has pioneered the chemical synthesis of modified tRNA oligonucleotides. Alltrna’s Chief Technology Officer William Kiesman explains about manufacturing tRNAs and more in this BioProcess International interview: https://lnkd.in/dmKfkQDX #tRNA #RNA #tRNAmedicines #manufacturing #rarediseases #geneticmedicines
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Thank you to Tom DiLenge and all the speakers for driving crucial conversations that inspire change. At Alltrna, we are committed to transforming medicine, boldly building a new future for patients and accelerating drug development for rare diseases. #tRNAmedicines? #tRNA #rarediseases #raredisease #StopCodonDisease? #geneticmedicines
Yesterday’s NORD Summit on Rare Disease Innovation was a great success. I had the pleasure of discussing Flagship's "blue sky" thinking about how to transform rare disease innovation by using platform-based approaches that can target hundreds, and potentially even thousands, of distinct rare genetic disaeses with a single genetic medicine -- such as the first-of-its-kind tRNA platform being developed by Flagship company Alltrna. Thanks to my fellow panelists and moderator for the engaging discussion!?
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How can we accelerate drug development and balance risk when a patient’s time is short? Alltrna CEO Michelle Werner was one of three parents who took the stage at the #STATSummit to discuss building biotech companies and changing drug development paradigms in a race against time to bring new treatments for #rarediseases that affect their children. Read the STAT story: https://lnkd.in/gt99m5ND
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Not all RNAs are created equal. tRNAs have some incredible therapeutic potential, but also unique challenges in terms of sequencing and chemical synthesis. In this Q&A with Drug Discovery World, Caroline K?hrer, Alltrna's Senior Vice President of Discovery Platform, breaks down the biology and how Alltrna is harnessing it to create tRNA therapeutics that can unify the treatment of diseases based on shared genetic mutations and accelerate rare disease drug development for millions. Read the article here: https://lnkd.in/egAY6_nC #RNA #tRNAmedicines #tRNAbiology #rarediseases #geneticmedicines #programmablemedicines #AI #machinelearning #StopCodonDisease
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?? Meet Caffrey and his new service dog and best friend, Ticket ????. They came by Alltrna today to spend time with the team and celebrate #NationalServiceDogMonth! Caffrey, the son of our CEO, lives with Duchenne muscular dystrophy, and his service dog helps him live more confidently and independently. We are proud to support accessibility, and Alltrna is always a welcoming space for service dogs. It was an honor to welcome Caffrey and Ticket and learn from them!