Aliri Bioanalysis

?? 5 Methods for Oligonucleotide Analysis: Oligonucleotides (OGNTs) provide the opportunity to target diseases at their molecular level by manipulating gene expression. There are five main approaches to bioanalysis of OGNTs, each of which has its advantages and disadvantages: ?? LC/UV? ?? LC/MS/MS? ?? Hybridization LF/FD? ?? LC/HRMS? ?? Hybridization Elisa? ? Download this helpful infographic to learn more about each method and identify the right choice for your development program.?https://lnkd.in/eCWVQEnG #Oligonucleotides #Oligos #Bioanalysis #CRO #ScienceStrong?

?? Unlock AI-driven data that will help predict the efficacy of your molecule years earlier...before it’s too late! In a recent interview for Drug Development & Delivery magazine, Corinne Ramos, Ph.D., Director of Research & Development at Aliri Bioanalysis shares,? “Aliri’s data scientists are leveraging custom AI scripts to help our sponsors identify and better understand the drug mechanism of action at the single-cell level with far greater certainty than tradi-tional methods. The power of AI in conjunction with genomic, proteomic, and metabolomic analysis is a game-changer that provides our clients an edge when selecting drug candidates that are most likely to succeed in the clinic – while saving them time, money, and from costly mistakes in the process.” Work with our highly trained team of data scientists to de-risk and accelerate your development program to the clinic and beyond.? https://lnkd.in/e_e7yhDX

?? Small vs. large molecules: How to pick the right bioanalytical method? Appropriate testing techniques vary by molecule type, the individual characteristics of the drug, and its intended use.? Regardless of the molecule size, it is important to validate appropriate methods that can accurately determine the concentration and the bioactivity of the drug over time.? There are no regulations requiring specific methods for every drug class; instead, the goal is always to optimize the available published research and acquired data to develop scientifically appropriate methods. Download this infographic to learn more about how to choose the right method for your molecule: https://lnkd.in/e5XcqprH #SmallMolecule #LargeMolecule #bioanalysis #CRO #MethodValidation

Aliri Bioanalysis scientists at our lab in Lille, France, recently developed a composite biomarker that integrates the spatial distribution of metabolites with genomic profiling, transcending traditional methods of predicting patient responses to immuno-oncology therapy. Learn more: https://lnkd.in/euVkZhQA #SpatialBiomarkers #GenomicProfiling #PatientStratification #ImmunoOncology

Last Friday we asked you to guess how many unique drugs and metabolites Aliri Bioanalysis has analyzed over the last three decades... If you guessed over 2,500, you are correct! Our passionate team of industry-leading scientists are constantly innovating and adopting the latest technology to?better serve our sponsors and their life-saving molecules. Reach out to learn how we can support your development program! https://lnkd.in/ekbP5Rf8

?? Poll Time ?? ? ? At Aliri, we have over 30 years of experience supporting the development of life-saving medications. We’re curious if you can guess how many unique drugs and metabolites we've provided bioanalytical and spatial bioanalytical services for so far!?

There is no project too complex for our team to support! ?? In a recent interview for Drug Development & Delivery magazine, Jim Wilfahrt, Chief Operations?Officer at Aliri Bioanalysis, shares, “We’ve rescued many programs that hit a wall at other labs. One customer told us that when three other labs failed, Aliri was their last hope. We not only found a solution that worked so their program could proceed, but in the process, saved that biotech company from certain collapse.” Our team of experts has 30+ years of experience tackling complex studies across all modalities and seeks to find innovative solutions to meet your most challenging molecules and timelines. Reach out to get started!?https://lnkd.in/eDrci-Ky #CRO #Bioanalysis #SpatialBiology #ScienceStrong

Explore why sponsors are switching from Ligand-Binding Assays (LBA) to Liquid Chromatography-Mass Spectrometry (LC-MS) for large molecule protein analysis in our recent webinar. Key learnings include: ?? The benefits of LC-MS, including its speed, cost efficiency, and data specificity ?? Technology considerations and market trends ?? When to choose LC-MS over LBA ?? Advancements in biomarker discovery and transgenic protein analysis, especially for mRNA drugs Don't miss insights from our scientific rock stars! ???? ?? Watch on-demand now: https://bit.ly/4exOxSU #Bioanalysis #Webinar #LCMS #Biotechnology

Aliri has pioneered #Oligonucleotide analysis and solved many scientific challenges over the last two decades. This set of experiments on antisense oligonucleotide (ASO) extraction optimization is yet another example from our lab in Salt Lake City (originally Tandem Labs) of how our experienced team works diligently with many tools at their disposal to provide the best solutions and techniques to our sponsors in quantifying their drug of interest. Download this scientific poster to learn more: https://lnkd.in/e3fxzzKB #Antisense #Oligonucleotide #Extraction #Optimization

Need quick bioanalytical support for your most challenging programs? We can handle it! When timelines are tight and stakes are high, our team has the expertise needed to get decision-making data in your hands fast, so you can hit your next milestone. In a recent interview for Drug Development & Delivery online, Shane Karnik, Sen-ior Laboratory Director at Aliri Bioanalysis shares, “We are quite used to developing and validating custom assays for sponsors, usually in a matter of days, to keep their development projects on track.” Reach out to learn more about how our experienced team of scientists can work within your timeline to help advance your large or small molecule quickly. https://lnkd.in/e_WYncRT #CRO #Bioanalysis #ScienceStrong #CustomAssay #SmallMolecule #LargeMolecule