AVAC

New data presented at CROI shows the devastating impact treatment interruptions can have on babies born with HIV who lose access to lifesaving treatment. Sudden termination of HIV programs, like the terminations of our work in Eswatini and Lesotho, put children in danger. Children's health cannot wait! Read the full article: https://lnkd.in/ejUmAfi7 International Antiviral Society–USA

Post for ID/HIV enthusiasts: My take homes from CROI 2025 were mainly about PrEP- it was exciting! LA CAB PrEP performed very well in a large real world (Kaiser Permanente) US cohort ( n=141) and in the PILLAR study (n=201). There were no incident infections, persistence was very high, >90% coverage and it reached people who had never taken PrEP (25% in KP cohort). In a diverse Brazilian PrEP cohort all of whom were tested for HIV (genXpert test at baseline), 86% chose CAB LA. Adherence on CAB was very high, coverage was higher than oral PrEP and there were no incident infections on CAB. 6% discontinued CAB mainly due to side effects. VL monitoring in 084 study had low PPV as it did in 083. Achieving viral suppression in people with INSTI resistance was possible using INSTI-based regimens either directly or after period of suppression on NNRTI/PI regimen. LEN: In adolescents in PURPOSE 1 , there were 0 infections and PK was similar to adults. The first YEARLY LEN (an IM not SC) injection has been studied in phase 1 in 20 people. Drug levels were higher than 6-monthly SC LEN, safe, well tolerated with no nodules. British HIV Association (BHIVA) The British Association for Sexual Health and HIV (BASHH)

“The Executive not only claims his constitutional authority to determine?how?to spend appropriated funds, but usurps Congress’s exclusive authority to dictate?whether?the funds should be spent in the first place,” U.S. District Judge Amir Ali stated in his preliminary injunction, which was filed Monday night.

Truly phenomenal talk in the #croi2025 opening session from Rebecca Denison Diagnosed with HIV in 1990, Rebecca shared her incredible journey, joining ACTUP, founding WORLD (https://lnkd.in/ep-ZT62b), and having HIV-negative twin daughters (one of whom was in the audience, alongside her dad & the doctor who delivered her & her sister!!). Rebecca called out the misinformation peddled by the new US Secretary of Health including his assertion that the "gay lifestyle" caused AIDS, not HIV....."Hey RFK, I never used poppers" She spoke eloquently of her own privilege, her freedom from institutional censorship & the irreversible harm of the ongoing decimation of Global HIV funding. If you're at CROI please join the rally to SAVE OUR SCIENCES on Monday 10 Match at 6pm. link below. if you don't have a US email you can't register via the link but you CAN still join. Registration not required ?? "Fear is a reaction, courage is a decision" https://p2a.co/YS8dsxA

Post from San Francisco: I have been re-posting recently to amplify the voices of my US colleagues about the war on science and public health that is taking place in the US and the cuts to public funding for PEPFAR HIV programmes supporting treatment and HIV prevention for millions worldwide. It seems that some UK colleagues are not aware of the extent of other domestic policies. So read on for more… Unlike federally employed US scientists I have been able to travel here(they are subject to a travel ban). I am able to present data that reports on gender identity (this is now banned for government employees as part of the war on ‘woke’ which prevents all research about transgender people and stops them receiving gender affirming hormones). National datasets with data or guidelines on gender identity and sexuality have been removed off CDC (centre for disease control ) government websites in recent months. I am here to listen to science on vaccines at a time when high profile meetings on flu strains have been cancelled/ postponed here. So I am at CROI feeling very fortunate to be able to support science by presenting late-breaking data on a novel HIV drug (Islatravir) with potential as a core agent in future long-acting therapies. AND by speaking up. If you haven’t heard about this please support science and repost this. British HIV Association (BHIVA) The British Association for Sexual Health and HIV (BASHH)

???Join us for our virtual event, “Advancing Sexual and Reproductive Health and Rights: Moving Forward post-the 2024 US Election,” which will take place on Wednesday, March 12th, at 9:00 am PDT/12:00 pm EDT/5:00 pm CET. The 2024 US Presidential Election is already having profound impacts on the future of sexual and reproductive health and rights not only in the United States, but around the world. This panel will explicitly consider this political moment – discussing areas to push forward, lines to hold, and opportunities for global solidarity in SRHR. Our speakers include: 1.?????Sekai Chikowero, Vice President of Programs,?EngenderHealth 2.????Francine Coeytaux,?Co-Founder and Strategic Advisor,?Plan C Pills? 3.?????Eszter Kism?di,?Chief Executive,?Sexual and Reproductive Health Matters 4.????Mitchell Warren, Executive Director,?AVAC (dedicated to expanding HIV prevention options) The dialogue will be moderated by IIGH Director Sofia Gruskin. ???Learn more and register here:?https://lnkd.in/gHrVq_5V

The latest PxWire from AVAC highlights major setbacks in the #HIV response: "Policies by the new US Presidential administration have derailed the entire field, potentially setting back the HIV response by years, if not decades." ?? https://ow.ly/vt9j50VcHCs