Work with us on your #Epigenetics Services projects - we're here to help with lower pricing & flexible payment options during these challenging times. Learn more ?? https://bit.ly/3BTHnJQ
Active Motif
生物技术研究
Carlsbad，California 8,097 位关注者
Enabling #Epigenetics #Genomics & #Transcriptomics Research!
关于我们
What is exciting about the area we work in Epigenomics is the systematic analysis of the global state of gene expression not attributable to mutational changes across the entire genome. Epigenetic mechanisms are affected by external factors including development in utero and in childhood, environmental chemicals, drugs and pharmaceuticals, aging, and diet. Changes to the epigenetic landscape can have a profound impact on health and disease. Precise mapping and measurement of the epigenetic landscape offers the promise of predictive biomarkers of disease development, even before changes in gene expression have taken place. Epigenomics is the “OME” connecting Genomics to Transcriptomics and Proteomics allowing a Multiomics approach to disease research which will result in a higher yield of data that can be aggregated and analyzed to become actionable information. What does Active Motif offer Epigenetic methods and approaches require the use of high-quality antibodies and enzymes that have undergone strict validation criteria. This allows the development of robust assays for use in mechanistic studies, translational medicine, drug discovery and diagnostics. Active Motif’s Product Development Program takes emerging novel techniques, and develops them into innovative products that allow researchers to perform the assays in their own labs as well as feeding into their end to end services pipeline. Active Motif is building a platform based on their patented transposase based technologies to simplify the interrogation of chromatin, the dynamics of histone modifications, chromatin remodeling, DNA methylation, transcription factor binding, as well as short and long range gene regulation by non-coding regulatory regions. Our bioinformatics platform can take the data generated by these techniques and provide powerful insights into the epigenetic changes occurring in disease or in response to drugs.
- 网站
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https://www.activemotif.com
Active Motif的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- Carlsbad，California
- 类型
- 私人持股
- 创立
- 1999
- 领域
- Epigenetics、Genome wide epigenetic services、ChIP Seq、Transcription analysis、Histone antibodies、DNA methylation analysis、Gene regulation、Lab Services、Life Sciences、Laboratory Equipment、Transcriptomics、Recombinant Proteins、Longevity、Aging、Drug Discovery、ELISA Kits、Cell Biology、single cell 和multiome
地点
Active Motif员工
动态
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Active Motif转发了
Looking forward to welcoming Peter W Lewis from University of Wisconsin-Madison for our March All-Ireland Chromatin Consortium webinar on 'Dissecting the Biochemical Complexes Governing Gene Silencing' on March 28th! Register here: https://lnkd.in/eRTWwWe2 Active Motif
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Active Motif转发了
[NEW TechNote] Two of the most popular staining methods – Trypan blue and acridine orange / propidium iodide (AOPI) are compared by our scientists! See their data and insights, best uses and considerations for counting whole cells and nuclear staining. Get the Guide ?? https://lnkd.in/grhgH6Jj
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Active Motif转发了
Senior FAS, Group leader/manager, Product manager, International account manager, Services consultant, Business Development
A day of learning at New York city with my colleague Kevin Celestrin from Active Motif Photo 1: A quick search of "prostate cancer frequency" shows that it is the most common cancer ?? in men, excluding skin cancer, with highest rates in North America , Europe, and Australia. Today, I had the privilege of meeting a scientist who studies this disease - Juan Arriaga, PhD, Assistant Professor at the Departments of Oncological Sciences and Urology, Icahn School of Medicine at Mount Sinai. Dr. Arriaga explained his amazing work on the biology associated with prostate cancer metastasis. His dedication to prostate cancer research earned him several awards including the prestigious Young Investigator Award?from Prostate Cancer Foundation?https://www.pcf.org/?You can learn more about how he uses epigenetics, in vivo and genome-wide CRISPR screening for therapeutic developments against this disease here? https://lnkd.in/gRbUZq7W Photo 2: You may know that white blood cells (WBC) ?? combat disease and infection, and a type of WBC is B cells. But did you know that cancer can originate in B cells? It is called B-cell lymphoma which can occur at any age, and it has several types. Today, we got to learn so much about this disease from David Dominguez-Sola, MD, PhD, Assistant Professor in the Departments of Oncological Sciences and Pathology, Icahn School of Medicine at Mount Sinai. It was fascinating to hear about his research on B cell lymphomas, focusing on the roles of cancer initiation and oncogenes on the biology of cells and tissues. To know more about in vivo, in vitro and epigenetics approaches developed by his lab to study B cell lymphomas, please visit?https://lnkd.in/gpu6Reh9 Photo 3: We were lucky to see #ArtoftheBrain an exhibition of fantastic images of tissues ?? captured by sophisticated microscopy ?? and spatial biology techniques. You do not have to be a biologist to be awed by the images. Even cooler, the scientists added simple explanations of complex processes captured in the images for everyone to understand and appreciate ?? Limited time only, if you are here. Photos: 3a - Building, 3b - Exhibition. Photo 4: With Navneet Dogra, PhD, Assistant Professor in Genetics and Genomic Sciences and Pathology at Icahn School of Medicine at Mount Sinai. Dr. Dogra has unique versatility in expertise including nanoparticles assisted drug delivery, cancer liquid biopsy, exosomes, extracellular vesicles, viruses, bioengineering, and cell-free DNA ??, RNA and proteins. He may look familiar because you may have seen him in multiple high profile media outlets where his research is featured, and won several prestigious awards. Fun fact: He is also a talented painter ??, I know because we are friends from grad school ?? Dr. Dogra's lab https://lnkd.in/giENBhZp Photo 5: Rockefeller Research Laboratories building where some programs of Memorial Sloan Kettering Cancer Center are located.
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Active Motif转发了
Ending soon ?? don't miss a chance to enter our drawing - you may win our DNA Library Kit for Illumina. Just minutes to enter ?? https://bit.ly/485spwe #ASCB25 #DNA #Illumina #CUTnRUN #Genomics #Biotech
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Active Motif转发了
Time to BULK UP...on recombinant proteins & active epigenetic enzymes! Save BIG on 1 mg sizes. ?? https://bit.ly/485spwe #CancerResearch #Pharmaceuticals #Biotechnology #AACR25
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Time to BULK UP...on recombinant proteins & active epigenetic enzymes! Save BIG on 1 mg sizes. ?? https://bit.ly/485spwe #CancerResearch #Pharmaceuticals #Biotechnology #AACR25
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Active Motif转发了
Take a moment to consider #SingleCell Multiome Service || Measure gene expression AND open chromatin states from the same cell! Get a quote fast ?? https://bit.ly/4evb7v0 #ASCB2024 #genomics #immunology #neurobiology #proteomics
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Active Motif转发了
Contact us for new 2025 pricing on RNA-Seq Services. Get a Deal ?? https://bit.ly/47ZkUqt ?? #Epigenetics #Genomics #RNASeq #RNA #DrugDiscovery #ASHG24
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