American Association of Pharmaceutical Scientists (AAPS) | @aapscomms

#DYK ?? Freeze-drying is crucial for effective, shelf-stable medicines. Contribute to the #AAPSOpen special issue on Freeze Drying Tech, honoring AAPS Fellow & global leader in the field, Dr. Steven L. Nail! ?? Submit by April 30, 2025. #FreezeDrying

?? Save the Date for the 2025 Summer Scientific Forum! ?? ?? July 14-17 | ?? Indianapolis, IN Join leading scientists and experts as we dive into innovative technologies, new approaches to current challenges, and regulatory updates in #bioanalysis and #pharmaceutical analysis. ?? Why attend? 86% of past attendees applied new knowledge to their work. Registration is now open! #AAPSForum

The American Association of Pharmaceutical Scientists (AAPS)-Modified Release Community (MRC) Webinar Invitation. American Association of Pharmaceutical Scientists (AAPS) | American Association of Pharmaceutical Scientists (AAPS) | @aapscomms René Holm, PhD, Professor, University of Southern Denmark, Odense, Denmark, 'Suspensions for long-acting injectables – recent insights' Webinar - Wednesday, April 2nd, 2025, 12-1:00 PM EST How to join: https://lnkd.in/g3C33bDR Webinar Summary - To address the suboptimal treatment outcomes of chronic conditions like schizophrenia and poor patient compliance, various formulation strategies have been explored. One approach is the use of long-acting injectables (LAIs), which can release an active pharmaceutical ingredient over weeks to months. These formulations often utilize aqueous suspensions with crystalline drug particles engineered to maintain a predefined plasma concentration profile by controlling the particle sizes. The production of nanosuspensions typically involves wet bead media milling reducing larger drug particles to smaller ones through mechanical friction in an aqueous stabilizer vehicle. However, the inherent thermodynamic instability of these systems can affect their long-term stability. To counteract issues like agglomeration and Ostwald ripening, stabilizers such as surfactants and polymers are added preventing inter-particle forces through electrostatic repulsion and steric stabilization. The choice and concentration of stabilizers depend on the specific formulation and the physicochemical properties of the drug, making the selection process complex and often reliant on trial and error relying on empirical data. In this talk, recent insight into the stability behavior of suspensions, with respect to the particle size growth, and also resuspendability are discussed, as well as some of the initial learning applying machine learning (ML) to suspension formulations to understand these systems even further. René Holm, David Cipolla, Vivek Agrahari, Sravan Kumar Patel, Sai HS Boddu, Alejandro J. Paredes, Kanika Suri, Ph.D., Priyanka Kancherla, Samir Senapati, PhD, Hiren Patel, Madhulika Banerjee, Mitra Mosharraf, PhD, MBA

Understand the role of #excipients in #pharmaceutical #formulations. Join AAPS for a #webinar, Power of Multifunctional Excipients: How They're Helping Drug Delivery, on April 17. ?? AAPS members receive immediate and free access to numerous archived AAPS webinars, along with many other high-value benefits. Join today! ??

?? Calling all AAPS members! ?? Want to make an impact at #PharmSci360 in San Antonio, TX, Nov 9-12, 2025? We need #volunteers for the 2025 PharmSci 360 Rapid Fire Committee! ?? Submit your application by April 4, 2025, 11:59 pm ET ?? Learn more & apply now!

Don't miss this new #publication from The AAPS Journal ?? Here, #researchers evaluate small ankyrin repeat proteins called Ankyrons that were generated to bind with high affinity to the SARS-CoV-2 virus. This research underscores the potential of Ankyrons as a fast, cost-effective platform for developing antiviral tools. ?? Read the full details here: https://lnkd.in/gpPS9s65 #AAPSJ

Interphex is just around the corner! April 1-3 in NYC and I hope to see you there. Early bird pricing is still available for another week, so what are you waiting for? American Association of Pharmaceutical Scientists (AAPS) | @aapscomms INTERPHEX Global

Next week, attend this free AAPS web event to see how #AI is reshaping #qualitycontrol and compliance. On March 17, Rafiq Islam and Mohammed Moin of Somru BioScience Inc. will explore three real-world case studies, examining how AI-QMS ensured compliance for #bioanalytical data, #immunogenicity cut-point analysis, and data integrity monitoring. All AAPS members receive immediate and free access to numerous archived AAPS eLearning sessions similar to this one!

Every year I attend #AAPS's #PharmSci360 for the science and networking. While I focus on the Bioanalytical Track, I always pick up a session from several of the other tracks to learn more about the cutting edge work going on in Discovery and Basic Research, Translational Research, Clinical Pharmacology, or Formulations. This year will be no different. If you have research to share, there is still time to submit it for this year's PharmSci360- whether you want to present a Symposium or Rapid Fire: Symposium Proposal Submission Deadline: April 8, 5 PM ET ? Rapid Fire Submission Deadline: June 13, 5 PM ET I'm inviting you to submit your proposal for a session at this year’s event in San Antonio and hope to see you there! You can check out the program themes and submit today! ???https://lnkd.in/eiKz3u7E #PharmSci360? ?

?? Don't miss this! The 2025 Boston Society Gene & Cell Therapy Conference?is scheduled for March 20-21?at BMS, Cambridge, MA. Join us as top experts share cutting-edge insights on CMC, regulatory perspectives, bioanalytical assays, emerging cell therapies, lessons learned from approved cell therapies?and more. Check out the full speaker lineup and register today! ?? #GeneTherapy #CellTherapy #BSGCT2025