10x Genomics的封面图片
10x Genomics

10x Genomics

生物技术研究

Pleasanton,California 244,942 位关注者

Powering researchers’ insights with innovative single cell, spatial biology, & in situ tools. ????

关于我们

Cells are the basic unit of life. They power everything we do, and unlocking their secrets is the key to advancing our knowledge of every facet of biology, from development to disease. Our single cell, spatial, and in situ tools enable researchers to answer pressing questions about cells and their functional contributions to oncology, immunology, neuroscience, and much more—as evidenced by more than 5,500 publications citing our technology. We are dedicated to building the best products, delivering the best customer experience, and creating the best team to fuel new scientific discovery, no matter how challenging. And we won’t stop until all of the cells’ secrets are revealed.

网站
https://10xgenomics.com
所属行业
生物技术研究
规模
1,001-5,000 人
总部
Pleasanton,California
类型
上市公司
创立
2012

地点

  • 主要

    6230 Stoneridge Mall Rd

    US,California,Pleasanton,94588

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10x Genomics员工

动态

  • 查看10x Genomics的组织主页

    244,942 位关注者

    #InternationalWomensDay is here, and our #WomensHistoryMonth celebration is in full swing! This month is about recognizing the strength, achievements, and impact of women past and present. Earlier this week, we kicked things off with an inspiring panel discussion and Q&A, where 10x #womeninSTEM shared their experiences navigating challenges, breaking barriers, and shaping the future. The conversation was filled with powerful insights, setting the stage for a month of reflection, learning, and action. And we’re not stopping here! There’s more to come, including workshops, a movie night, book club discussions, and a closing celebration—all dedicated to honoring the voices and stories of women. ??

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  • 查看10x Genomics的组织主页

    244,942 位关注者

    The scope and scale of this work is nothing short of breathtaking. All we can say is congratulations?Eduard Porta Pardo, and that your work and approach is demonstrating just how spatial bio is making a brighter future for clinical and drug discovery work. Well done!

    查看Eduard Porta Pardo的档案

    Junior Group Leader en Josep Carreras Leukaemia Research Institute

    ???New preprint alert!??? Excited to share our latest work from the?DUTRENEO trial, now available on?medRxiv! ???? In this?prospective, biomarker-driven study, we tested whether the?18-gene Tumor Inflammation Signature (TIS)could guide treatment selection for?muscle-invasive bladder cancer (MIBC)?patients receiving neoadjuvant?immune checkpoint inhibitors (ICI) or chemotherapy (NAC). While TIS?alone?did not significantly enrich for ICI responders, we generated?one of the largest spatial transcriptomics datasets in bladder cancer?(Visium, Xenium) and integrated?multi-omics?to reveal key insights into?tumor-immune interactions and treatment resistance: ???Spatial immune proximity drives ICI response?– Cancer-immune colocalization, not just inflammation, predicts benefit.?Where?immune cells are?matters. ???Phenotypic plasticity fuels NAC resistance?– Not genetic diversity, but?transcriptional reprogramming?allows tumors to evade chemotherapy. ???Bulk RNA "immune" signatures are misleading?– Response-associated genes primarily originate from?cancer cells, not the microenvironment. ???Checkpoint expression alone is not enough?– The?spatial context of immune checkpoints?and?cellular neighborhoods?determines therapeutic response. ???Retrospective ≠ prospective biomarkers?– TIS was promising in retrospective studies but did not prospectively enrich for responders, underscoring the?need for spatial and multi-modal biomarkers in clinical trials. With?spatial transcriptomics and AI poised to transform precision oncology, these findings provide a?roadmap for integrating spatial biomarkers into future clinical trials. Huge thanks to our amazing collaborators—looking forward to discussions and feedback from the community! ?? Read the full preprint: https://lnkd.in/dz2H_kZ7 #BladderCancer #SpatialTranscriptomics #Immunotherapy #PrecisionOncology #DUTRENEO #CancerResearch #Visium #Xenium #AIinOncology

  • 查看10x Genomics的组织主页

    244,942 位关注者

    Though ~50 million Americans live with an autoimmune disease, none currently have a cure. Take inflammatory bowel disease, for example. Though its prevalence in adults increased by 123% between 2007 and 2016, conditions like Crohn’s disease and ulcerative colitis remain lifelong challenges. Luckily, researchers are trying to change that. In honor of #AutoimmuneAwarenessMonth, find out how scientists built a single cell atlas for Crohn’s disease. Read the blog: https://lnkd.in/gkUfXHht

  • 查看10x Genomics的组织主页

    244,942 位关注者

    Since the beginning, our question has always been, “What’s next?” Our mission looks toward a future with improved outcomes for human health, and we want to do everything we can to help science get there. So, we’re thrilled that LexisNexis has once again named us one of the Top 100 Global Innovators for 2025 in their annual Innovation Momentum Report, and we gladly share this recognition with the scientists around the world who are using our technologies to make groundbreaking discoveries. https://bit.ly/42XQ3dC #Top100Innovators #InnovationMomentum

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  • 查看10x Genomics的组织主页

    244,942 位关注者

    Join our webinar, co-hosted with Owkin, on "Harnessing spatial biology and AI to develop targeted therapeutic strategies." Our experts will explore how spatial omics is enabling Owkin to generate novel hypotheses and discoveries, and how the combination of spatial biology and AI can optimize the development of antibody-drug conjugate (ADC) strategies by selecting the best indications and populations. Speakers: ??Atanas Kamburov, Head of Pharma Solutions Data Science, Owkin ??Trisha Bartlett, Associate Director Strategic Marketing, 10x Genomics ??? Date: February 26, 2025 ? Time: 11 AM EDT / 5 PM CET ?? Register today: https://lnkd.in/gFAj2MpG

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