.406 Ventures

🚀 Big congratulations to .406 portfolio company RAD Security on its Series A! Rad Security has developed an AI-driven defense platform that improves operational efficiency for security teams, and enables the safe and secure use of cloud and AI workloads within an organization. We are excited to support RAD as they scale their impact—looking forward to what’s ahead! 👏 Go, Brooke M., Jimmy Mesta 🤙, and team! You can read more (and see RAD's new website!) here: https://bit.ly/4ktoNdt #CyberSecurity #AI #StartupGrowth #SeriesA #AIsecurity #cloudsec🚀 Greg Dracon

Exciting News for Friday! 🎉 We’re thrilled that .406 Ventures has been recognized as one of five VC firms to watch by Laura Lovett in Behavioral Health Business! At .406, we are deeply committed to radically improving behavioral health by backing innovative companies that drive real impact. We’re proud to support incredible teams bringing innovative, evidence-based, and insurance-reimbursable care options to the most pressing mental health challenges including pediatric OCD and severe anxiety, PTSD, eating disorders, autism, substance use disorder, and beyond. A special shout-out to our portfolio companies that were highlighted: o  AbleTo Inc. (acquired by Optum) o  Cortica (recently named one of 43 startups to bet your career on by Business Insider) o  Equip o  InStride Health o  Nema Health o  Wayspring o  FamilyWell Health o  Better Life Partners Onwards! Liam Donohue, Trip Hofer, Payal Agrawal Divakaran, Kathryn Taylor Reddy, Rebecca Redfield

Startup fundraising is never easy—but having the right insights can make all the difference. Last week, .406 Partner Greg Dracon joined an investor panel at the VentureFizz Startup Fundraising Conference 2025 to talk all things capital raising. Huge thanks to Keith Cline for putting together such an engaging event! Greg was in great company alongside: 🔹 Maia Heymann – Converge VC 🔹 Vivjan Myrto – Hyperplane 🔹Matthew Bellows – Grit Capital Partners 🎤 Moderated by Thara Pillai– Harvard Innovation Labs Among other topics, they covered: 💡 The right time to raise capital (Hint: Live on bootstrapping and revenue as long as you can). ⚠️ Pitfalls of fundraising—especially why it’s crucial to find investors who truly understand your space. 🎯 What VCs look for in a CEO— self-awareness, resilience, ability to sell, and a whole lot more. One of Greg’s top suggestions? Don't build to sell - build something with enduring value and there are always opportunities to exit.🔥

🎧 🫀 To celebrate Heart Health Month, .406 Partner (and guest host!) Payal Agrawal Divakaran speaks with founder and CEO of .406 portfolio company Heartbeat Health, Jeffrey Wessler, on this year’s first episode of Breaking Health podcast. They discuss virtual cardiovascular healthcare, how Heartbeat cracked the code on telemedicine-based treatment, and the power alley for physician entrepreneurs in VC-backed companies. Listen now and enjoy: https://bit.ly/4i0we9K

Last week .406 Partner Graham Brooks (The Tuck School of Business at Dartmouth, 2002) spent time on the Dartmouth College campus, sharing insights with graduate students in both business and engineering. At Tuck’s annual Private Equity and Venture Capital Conference, Graham joined Betsabeh Madani-Hermann (T’13) and former classmate Matt Fates (T’02) for a panel moderated by MBA candidate Larissa Marten (T’25) on Navigating Venture Capital, discussing different fund strategies and the risks of overfunding that arise when large funds need to put capital to work. Over at Thayer School of Engineering at Dartmouth, he led a session for Technology Innovation and Entrepreneurship, a graduate-level course taught by Professor Trent Staats. He walked PhD and master’s students through the fundraising process, fundraising strategies, and the Student Fellows Program he leads at .406 for student entrepreneurs at the undergraduate and graduate school levels. It’s always great to see Graham back at his alma mater (Go, Green!) sharing his expertise with the next gen.

Three cheers for the three .406 portfolio companies that were recognized by Digital Health New York. Diana Health (We're Hiring!) and Heartbeat Health earned spots on the Digital Health 100, the annual list that highlights the most innovative companies in the New York region. And, Nomad Health is included in the Hall of Fame, a testament to its effect on healthcare! 👏 👏 👏 We are thrilled to see each of these company’s groundbreaking work in women’s health, virtual cardiology care, and healthcare staffing being recognized for making a real impact in the healthcare ecosystem. Learn more about the latest trends in the 2025 New York Healthcare Innovation Report: https://lnkd.in/gcUA3J7Q Congratulations to all! #DH100 Kate Condliffe, Jeffrey Wessler, Justin Lambert Liam Donohue, Payal Agrawal Divakaran, Kathryn Taylor Reddy

There are inflection points in a company's trajectory that make us pause, reflecting in deep pride to be on the journey. This is one of them. Hats off to Heartbeat Health on publishing an innovative, peer-reviewed study on the outcomes of their virtual cardiovascular care. Jeffrey Wessler's, Jana M. Goldberg, MD, FACC's, and the team's commitment to clinical excellence is inspiring. 🌟 Liam Donohue Trip Hofer Rebecca Redfield

Big news from .406 portfolio company Lynx! Lynx has raised a $27M oversubscribed funding round to fuel the next leg of its journey to revolutionize healthcare payments. We are thrilled to have participated with existing investors Frist Cressey Ventures and Obvious Ventures, alongside new investors Flare Capital Partners who led the round, CVS Health Ventures, and McKesson Ventures. Go, Matthew R., Isoken Abel, and team! We look forward to your next moves. You can read more here: https://bit.ly/4jK9rRj Liam Donohue, Kathryn Taylor Reddy

Looking forward to this session next week! Thanks to Keith Cline and VentureFizz for organizing! .406 Ventures

Dana-Farber Cancer Institute could not have found a better person to add to its Board of Trustees! .406 Ventures' Payal Agrawal Divakaran will bring smarts, passion and a level of engagement worthy of the world's premier cancer research and treatment center. Congratulations to both! Four new members elected to Dana-Farber Cancer Institute Board of Trustees https://lnkd.in/etBeXQZA