The 'use' keyword in PHP can make your code more readable, reusable, and maintainable. However, there are some best practices to follow to prevent confusion and errors. For example, you should use fully qualified names when declaring namespaces or classes with the 'namespace' or 'use' keywords. Additionally, aliases with the 'as' keyword should be used when importing namespaces or classes with the same name or a long name. When using the 'use' statement, you should place one per line and group them by type and purpose. Moreover, the 'use' keyword should only be used when importing something from another namespace or file; for anonymous functions, it should only be used when accessing variables from the parent scope. By understanding its purpose and syntax, as well as following these best practices, you can use the 'use' keyword effectively and efficiently for better web applications.